Fibroepithelioma of Pinkus (Basal cell carcinoma, fibroepithelioma of Pinkus type)

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Fibroepithelioma of Pinkus(Basal cell carcinoma,
fibroepithelioma of Pinkus type)

• Deba P Sarma, MD
• Omaha

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M 79, back
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Comment

• First described by Hermann Pinkus in 1953.
• It is a rare variation of basal cell carcinoma
  with very indolent
• clinical course.
• Unlike other histologic types of basal cell
  carcinoma, the tumor occurs commonly on the
  sun-protected skin of trunk, especially back.
• Presents as a slowly enlarging, fleshy, raised or
  pedunculated papilloma or achrochordon with a
  broad base on the trunk or the extremities.
• Age Older adults, MF
• Histology Fibroepithelioma of Pinkus shows long,
  thin, branching and anastomosing strands of basal
  cell carcinoma within in a fibrovascular stroma.
  Many strands show a connection with the
  epidermis. The basaloid strands show two types of
  cells a lighter staining cell comprising the
  bulk of the strand and peripheral, small darker
  cells showing palisading pattern.

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Unusual examples of fibroepithelioma of Pinkus

• Pan Z, Huynh N, Sarma DP. (2008).
  Fibroepithelioma of Pinkus in a 9-year-old boy a
  case report. Cases Journal 121. PMID 18588684
  PubMed indexed for MEDLINE
• Repertinger SK, Stevens T, Markin N, Klepacz H,
  Sarma DP.(2008). Fibroepithelioma of Pinkus with
  pleomorphic epithelial giant cells. Dermatology
  Online J 14(12)13. Pubmed- indexed for
  MEDLINE.