A factorial randomized trial of blood pressure lowering and intensive glucose control in 11,140 patients with type 2 diabetes

1
ADVANCE Renal Events by Systolic BP Achieved
During Follow-up
Adjusted for age, sex, HbA1c, serum lipids, BMI,
smoking, alcohol use, and study drug Adapted from
Bulpitt C. ESH 2008.
2
HYVET Analysis of Total Mortality andCV Events
in Predefined Subgroups
Total Mortality Cardiovascular Events
n HR (95 CI) HR (95 CI)
Men 1519 0.82 (0.62-1.11) 0.69 (0.50-0.96)
Women 2326 0.77 (0.66-0.99) 0.65 (0.49-0.88)
History of CVD 452 0.76 (0.48-1.20) 0.77 (0.46-1.29)
No history of CVD 3393 0.81 (0.65-0.99) 0.65 (0.51-0.83)
Adapted from Bulpitt C. ESH 2008. Adapted from Bulpitt C. ESH 2008. Adapted from Bulpitt C. ESH 2008. Adapted from Bulpitt C. ESH 2008.