?????(Aristotle, 384-322 BC)

1
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• ?????(Aristotle, 384-322 BC)
• ?????????????(?,?,?,?)
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• ?????????2000?

3
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• ???(Dalton, 1766-1844) ????

1808??? 1. ??(element)???(atom)??? 2.
???????? 3. ??????????????????? 4. ??????????
4
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1860????(Kekulé, 1829-1896)?????????????(Karlsruhe
)?????????????

• ????(Cannizzaro, 1826-1910)?????
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• ?????????,??H????1,H2????2

W1L O2/W1L H2 16/1 ? O ?????16
???????????????
??????????(1869?????????)
5
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???(Kekulé, 1829-1869)
1858 ?????????????? ????????? ??????????????????
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Jean Baptiste Biot (1774-1862)
??????? ???????????????????????
7
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8
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9
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???(Pasteur, 1822-1895)
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???? Paratartaric acid
??? Tartaric acid
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Jean Baptiste Biot (1774-1862) My dear child, I
have loved science so much all my life that this
makes my heart throb
12
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C EN News, 2003, Volume 81, Number 34, pp.
27-30.
13
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Vant Hoff, 1852-1911 Nobel prize 1901
1874 ???????????? ??????????? ?????????? ?????????
??????
1877 Kolbe a childish fantasy
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(No Transcript)
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(No Transcript)
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??????????????? ?????????????(meso)
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???????????????????? ?????????(racemic)? ????????
????????????
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• ??????
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• ??????????27?C??????????????

?????? ???????????? chance favors only the
prepared mind
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(No Transcript)
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????????
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?????? ?????????????(Penicillium
glaucum)?????,???????????????????
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???????
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AMP
?????
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DNA
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http//w3.dwm.ks.edu.tw/bio/activelearner/submenus
/part2index.html
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C E News, 2004, Volume 82, Number 24, pp. 47-62.
33
???????????????(Atorvastatin Calcium
Trihydrate) Atorvastatin???????statin??,????????LD
L-???????????????
34
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35
2,4-??? ?????

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????????????(chiral building block) ??? ????????

???????????????????? ????? ????(??)
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(No Transcript)
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?????? ? ???????
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Alfred Werner (1866-1919) Nobel prize, 1913
????????????????????????????????
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(No Transcript)
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(No Transcript)
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1911? ??????????????
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(No Transcript)
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??
(Noyori)
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(No Transcript)
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(No Transcript)
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(No Transcript)
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???Sharpless epoxidation
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????????????