Pathophysiology of digestion. Pathophysiology of liver - PowerPoint PPT Presentation

Loading...

PPT – Pathophysiology of digestion. Pathophysiology of liver PowerPoint presentation | free to download - id: 5f7fc4-NDA4Y



Loading


The Adobe Flash plugin is needed to view this content

Get the plugin now

View by Category
About This Presentation
Title:

Pathophysiology of digestion. Pathophysiology of liver

Description:

Title: Pathophysiology of digestion Author: User Last modified by: User Created Date: 1/7/2012 8:47:06 AM Document presentation format: (4:3) – PowerPoint PPT presentation

Number of Views:142
Avg rating:3.0/5.0
Slides: 45
Provided by: intranetT2
Category:

less

Write a Comment
User Comments (0)
Transcript and Presenter's Notes

Title: Pathophysiology of digestion. Pathophysiology of liver


1
Pathophysiology of digestion. Pathophysiology of
liver
2
Disorder of stomach secretory function
  • According to mechanism
  • Organic disturbances of stomach glands
  • Change I functional activity of secretory cells
  • According to kind of disturbance
  • Hypersecretion
  • Hyposecretion

3
Key-points for hypersecretion
4
  • The four inputs to parietal cells that regulate
    acid secretion
  • by controlling the transfer of the H,K-ATPase
    pumps in
  • cytoplasmic vesicle membranes to the plasma
    membrane.

5
Gastritis
6
Gastritis
7
Disorder of stomach motor function
  • Hypercinesis increased motility
  • Hypertonus increased degree of contraction
  • Hypocinesis - decreased motility
  • Hypotonus - decreased degree of contraction
  • Pathological reflexes
  • Nausea
  • Vomiting
  • Belching

8
(No Transcript)
9
(No Transcript)
10
(No Transcript)
11
(No Transcript)
12
Gastric Juice Secretion, Mucosal Protection and
Risk of Ulcer
13
Gastric Juice Secretion, Mucosal Protection and
Risk of Ulcer
14
Gastric Juice Secretion, Mucosal Protection and
Risk of Ulcer
15
(No Transcript)
16
(No Transcript)
17
Disorders After Stomach Surgery
18
Disorders After Stomach Surgery
19
Disorder of digestion in intestine
  • Disorders of the pick out of bile and pancreatic
    juice are accompanied by disorders of all types
    of digestion, development of putrefaction and
    fermentation in the intestine (at closing, or
    squeezing the excretory ducts of glands in cystic
    fibrosis mucoviscidosis, because of pancreatic
    cancer, acute and chronic pancreatitis and
    duodenitis, violating the neurohumoral mechanisms
    of regulation of secretion, particular functions
    of the vagus nerve, the allocation of secretin,
    cholecystokinin, pancreatic polypeptide).
  • Disorders of digestion of nutrients combined in
    maldigestion syndrome.
  • Malabsorption of substances in the gut combined
    into a syndrome, which is characterized by
    diarrhea, weight loss, protein deficiency, signs
    of hypovitaminosis.

20
(No Transcript)
21
Causes of Acute Pancreatitis
22
Consequences of Acute Pancreatitis
23
Causes of Chronic Pancreatitis
24
Consequences of Chronic Pancreatitis
25
(No Transcript)
26
(No Transcript)
27
Causes of Constipation
28
Consequences of Constipation and
(Pseudo-)Obstruction
29
Etiology and pathogenesis of liver insufficiency
  • Infectious agents (hepatitis B virus,
    tuberculosis bacillus, helmints) Hepatotropic
    poison (drugs - tetracycline, sulfonamides,
    industrial poisons - carbon tetrachloride,
    arsenic, chloroform, vegetable poisons -
    aflatoxin, muscarine) Physical impacts
    (ionizing radiation) Biological drugs
    (vaccines, serums) Violation of blood
    circulation (thrombosis, embolism, venous
    congestion) Endocrine pathology (diabetes
    mellitus, hyperthyroidism) Tumors Hereditary
    ensymopathy

30
Causes of Liver Failure
31
Consequences of Liver Failure
32
Fibrosis and Cirrhosis of the Liver
33
Fibrosis and Cirrhosis of the Liver
34
Clinical syndromes in liver injury
  • Lack of liver disorders manifested
  • its functions lesion metabolic (involved in
    carbohydrate, fat, protein metabolism, metabolism
    of vitamins, hormones, biologically active
    substances) protection (phagocytic and
    antitoxic) digestive and excretory (the
    formation and release of bile) hemodynamic
    (involved in maintaining systemic circulation).

35
Cholelithiasis Abnormal Cholesterol to Bile
Salt Ratio
36
Clinical syndromes of jaundice
  • Acholia associated with non-receipt of bile in
    the intestine due to violations of the formation
    and outflow of bile. Acholia manifested disorders
    of digestion and absorption of fats,
    hypovitaminosis A, E, K, decreased intake of
    unsaturated fatty acids of phospholipids to build
    cell membranes, intestinal motility violation,
    increasing decay and fermentation.
  • Dyscholia - violation of the physical-chemical
    properties of bile, causing it acquires the
    ability to form stones (due to genetic
    predisposition, poor nutrition, metabolic
    disorders, infectious-inflammatory processes,
    cholestasis).

37
Cholelithiasis Abnormal Cholesterol to Bile
Salt Ratio
38
(No Transcript)
39
(No Transcript)
40
(No Transcript)
41
(No Transcript)
42
Etiology and pathogenesis of jaundice
  • Jaundice - a syndrome caused by an increase in
    blood bilirubin (hemolytic, parenchymal,
    mechanical).
  • In hemolytic jaundice due to destruction of a
    large number of red blood cells accumulate
    indirect, protein bound bilirubin.
  • When parenchymal jaundice disturbed capture, and
    excretion of bilirubin in hepatocytes due to
    their injuries.
  • In mechanical jaundice occurs outflow obstruction
    of bile, compression of biliary tract tumor or
    scar, closing within a stone, worms, thick bile.

43
Mechanisms and Consequences of Cholestasis
44
Methods of experimental study of liver pathology
  • hepatic-cell failure simulating full or partial
    removal of the liver, the introduction of poisons
    (carbon tetrachloride, chloroform,
    trinitrotoluene) cholestatic model obtained by
    squising bile ducts by ligature hepatic
    vascular insufficiency simulating by overlapping
    portocaval anastomosis, ligation portal vein,
    hepatic vein, hepatic artery.
About PowerShow.com