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Iodine Isotopes

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Iodine Isotopes Chemistry & Radioactivity of Iodine Moataz Mohamed Radioisotope Therapy (RIT-I131) Rowan Mohamed – PowerPoint PPT presentation

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Title: Iodine Isotopes


1
Iodine Isotopes
  • Chemistry Radioactivity of Iodine
    Moataz Mohamed
  • Radioisotope Therapy (RIT-I131)
    Rowan Mohamed
  • Mohamed Shady

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I- Chemistry of Iodine
7
Discovery of Iodine
  • Discovery of
  • Iodine element
  • by
  • Bernard Courtois in 1811

8
Physical Properties
  • violet-dark gray solid
  • Density 5 g/cm3
  • Melting Point 114C
  • Boiling Point 185C

9
Atomic Properties
  • Atomic Weight 127
  • Electrons/shell 2,8,18,18,7
  • 53 Proton
  • 74 Neutron

10
Occurrence on Earth
11
II- Radioactivity of Iodine
12
Iodine isotopes
  • Isotopes are atoms of the same
  • element having the same
  • number of protons but different
  • number of neutrons.
  • There are 37 isotopes of Iodine
  • Ex I127, I129, I131
  • The only stable isotope of Iodine is I127.

13
Radiation Half-life Period
  • If radiation is a form of energy .. Then it can
    not be created (First Low of Thermodynamics).
  • So where does it come from???????????!
  • The source of radiation is the loss in mass
    (EMC2)
  • Half-life period is the time after which the mass
    will reach half of its initial value.
  • Half-life period is very important in determining
    the time needed for the radioactive substance to
    completely decay.

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III- Radioisotope Therapy (RIT-I131)
16
Radiotherapy Iodine-131
  • Definition.
  • Medical use of IONIZING RADIATION in treatment of
    Cancer and Malignant cells .
  • Radiotherapy Vs. Radiology ! !
  • History of Radiotherapy
  • Wilhelm Conrad Röntgen
  • Marie Curie

17
Radiotherapy Iodine-131
  • Mechanism of action
  • DAMAGE OF DNA..
  • Both strands ?
  • Damage is inherited
  • in cancerous cells .
  • Free radicals
  • ( hydroxyl radicals ) .

18
Radiotherapy Iodine-131
  • Radioisotope Therapy ( RIT )
  • INFUSION
  • MIBG Neuroblastoma
  • ORAL IODINE 131 Thyrotoxicosis
  • RADIOACTIVE GLASS Hepatic cancer

INGESTION
19
Radiotherapy Iodine-131
  • FELINE HYPERTHYRODISM
  • Procedure ..
  • Advantages ..
  • Disadvantages ..

20
Radiotherapy Iodine-131
  • Radiation protection.
  • Based on

Time
Distance
Shielding
21
Radiotherapy Iodine-131
  • 1- Reducing the time of an exposure reduces the
    effective dose proportionally.
  • 2- Increasing distance reduces dose due to the
    inverse square law .
  • 3- Adding shielding can also reduce radiation
    doses .

22
Thank You
  • References
  • http//en.wikipedia.org/wiki/Isotopes_of_iodine
  • Merck Index of Chemicals and Drugs, 9th ed.
  • General Chemistry (volume 2) by N.L. Glinka, Mir
    Publishing 1981
  • General Chemistry by Linus Pauling, 1947 ed.
  • Chemical Supplier Convicted of Diversion of
    Iodine

Moataz Mohamed
Rowan Mohamed
Muhamed Shady
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