DNA

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Gene Therapy and Cloning
Human Genome Project .
DNA Electro-phoresis
Misc.
Genetic Disorders
Genetic Engineering
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Alex Trebek
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Genetics Part 2 Review
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Name of the tool used to run a DNA electrophoresis
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What is agarose gel?
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What causes the DNA fragments to move
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What is electrical current?
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How the DNA fragments are divided once the gel is
finished running
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What is by size (small travel further)?
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Deer blood was found in the forest after hunting
season ended. DNA from this blood was compared to
meat and blood found in the suspects freezer.
Was the suspect guilty? Why or why not?
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Yes. The DNA fingerprints from the suspects
freezer match those found in the forest.
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According to the DNA gel electrophoresis to the
right, which is the least likely biological
offspring of the couple being tested?
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What is Child 2?
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Also known as Trisomy 21
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What is Down Syndrome?
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A human genetic disorder with a dominant
inheritance pattern
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What is Huntingtons disease?
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The name of the genetic disorder found in the
karyotype below
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What is Turner syndrome?
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Using the pedigree for Duchennes Muscular
Dystrophy below, if individual IV-1 had a
daughter and a son, what is the probability that
the daughter is a carrier and that the son
inherited the disorder?
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100 chance that the daughter will be a carrier
(fathers X has recessive allele).0 chance
that the son will inherit the disorder because
the mother is not a carrier.
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The inheritance pattern shown in the pedigree
below
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What is simple recessive?
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The thing that transplant DNA is placed into to
be delivered to the new host
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What is a vector?
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The purpose of gene therapy
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What is to cure genetic diseases?
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An exact genetic replicate
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What is the product of cloning?
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The name of the cell once the host DNA is removed
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What is an enucleated egg?
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A field of research that is currently using stem
cell technology
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What is regenerative medicine?
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The DNA of one organism is experimentally mixed
in with the DNA of another organism
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What is a transgenic organism?
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Anti-pest corn is an example of this
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What is a genetically modified organism (GMO)?
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The molecule that is used to cut DNA
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What is a restriction enzyme?
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Which restriction enzyme in the chart to the left
could be used to cut the DNA strand below?
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What is BamHI?
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Using the images below, what is the correct order
of the steps of the cloning procedure?
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What is 4, 2, 1, 3?
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The goal of the Human Genome Project
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What is to identify all human genes and sequence
all the DNA bases?
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The year the Human Genome Project was completed
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What is 2003?
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The organizations that led the Human Genome
Project
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What are the U.S. Dept of Energy and the National
Institutes of Health?
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3 non-human organisms whose genomes were
sequenced leading up to the Human Genome Project
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What are Escherichia coli bacteria, fruit fly,
and mouse?
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The significance of the goal end-date for the HGP
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What is the 50th anniversary of the description
of the double helix by Watson and Crick?
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An undifferentiated cell
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What is a stem cell?
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All the DNA in an organism
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What is a genome?
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DAILY DOUBLE
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Fill in the blanks in the table below
Human Blood Types Human Blood Types Human Blood Types Human Blood Types
Genotype Antigens Antibodies Produced Phenotype
A
B
AB
O
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Human Blood Types Human Blood Types Human Blood Types Human Blood Types
Genotype Antigens Antibodies Produced Phenotype
IAIA or IAi A B A
IBIB or IBi B A B
IAIB A and B A and B AB
ii none none O
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How long the Human Genome Project took to complete
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What is 13 years?
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What a restriction enzyme looks for to know where
to cut, and what forms when DNA is spliced
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What is a palindrome pattern and sticky or blunt
ends (depending on the enzyme)?
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FINAL JEOPARDY
Inheritance
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Using a Punnett Square answer the following
question. A colorblind man marries a woman who is
not colorblind. What are the possible genotypes
and phenotypes of their children?
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There are 2 genotype possibilities for the mother.
Xr
Y
Y
Xr
XR
XR
XR Y
XR Xr
XR Y
XR Xr
XR
XR Xr
XR Y
Xr
Xr Xr
XR Y
100 not colorblind (50 carrier females XRXr,
50 normal males XRY)
25 colorblind (XrXr) and 75 normal (25 carrier
females XRXr, 50 normal males XRY)