Where to Find the Course:

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Where to Find the Course Home Page
http//gspp.berkeley.edu/iths/RDStrategies/Home.ht
m Wiki https//bspace.berkeley.edu/portal
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Designing Strategies for Neglected Disease
Research Law 284.26 Public Policy 190/290
Course Overview Thinking Through the Problem
Stephen M. Maurer
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Where to Find the Course Home Page
http//gspp.berkeley.edu/iths/RDStrategies/Home.ht
m Wiki https//bspace.berkeley.edu/portal
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Owners Manual
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Owners Manual The power of instruction is
seldom of much efficacy except in those happy
dispositions where it is almost superfluous."
- Edward Gibbon
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Goals
This is nominally A Course About a Specific
Innovation Problem (Mostly Economics) But
you should think of it as A Course About RD
Incentives Ongoing Research A Course About
Giving Practical Advice (A Potential
Initiative) The Hard (Also Rewarding,
Interesting) Part
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Interdisciplinary Problems
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Three views - Cartoon intuition - How to do
public policy - A worked example.
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Interdisciplinary Problems
Drugs for U.S.
The Problem
Drugs for Developing World
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Interdisciplinary Problems
Drugs for U.S.
Political Science Redistribution
Drugs for Developing World
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Interdisciplinary Problems
Drugs for U.S.
Biology Engineering
Drugs for Developing World
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Interdisciplinary Problems
Drugs for U.S.
This Course (Primarily)
Drugs for Developing World
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Interdisciplinary Problems
Drugs for U.S.
Incentives Design
Drugs for Developing World
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Interdisciplinary Problems 2
Doing Public Policy - Define Goals ? Understand
? Identify Bottlenecks ?Design a
(Hopefully) Elegant Response.
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Interdisciplinary Problems 2

• Doing Public Policy
• - Define Goals ? Understand ?
• Identify Bottlenecks ?Design a
• (Hopefully) Elegant Response.
• Define Goals
• Choose an Objective Function!

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Interdisciplinary Problems 2
Doing Public Policy - Define Goals ? Understand
? Identify Bottlenecks ?Design a
(Hopefully) Elegant Response. 2.
Understand Take Theory Seriously - Pharma
doesnt want to prevent diseases, selling
drugs is more lucrative. - Prizes are only
paid if you get a drug. Making Contact
Between Theory and Evidence
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Interdisciplinary Problems 2
Doing Public Policy - Define Goals ? Understand
? Identify Bottlenecks ? Design a
(Hopefully) Elegant Response. 3. Identify
Bottlenecks - What are the Main Innovation
Challenges? - The Innovation Toolbox
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Interdisciplinary Problems 2
Doing Public Policy - Define Goals ? Understand
? Identify Bottlenecks ?Design a
(Hopefully) Elegant Response. 4. Design a
Response - No dominant incentive
mechanism - What are the Main Innovation
Challenges? - The Innovation Toolbox
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A Concrete Example Prizes vs. PPPs
Prizes How Big Should the Prize Be? 800m
115m PPPs Picking Winners Managing Outsourced
RD Getting the Best Ideas And Also Patents?
Access Pricing
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Recurring Themes
Innovation Economics Efficient
Procurement (Getting a Good Price) Usually
Efficiency How intense do we want RD effort
to be? Here Limited Budget How much will it
cost? Information Asymmetry/Agency
Problems (Managing Outsourced RD) Managers
Dont Know Everything Researchers May Have
Diverging Goals
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Recurring Themes
Innovation Economics, ctd Eliciting
Information (Getting Good Ideas) Good Ideas
are (Often) Widely Distributed Counterexamples
A prizes for reduced DALYs? A prize for
optimized drug compounds? Efficient
Access Patents Prices matter!
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Comment
Its a Great Idea, But Government Will Never
Listen A Lawyers Faith
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Roadmap
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Roadmap
Lecture Topic Speaker Week 1 Introduction
AK, SM Jan. 13-15 Defining The Goals Week
2 Disease Burdens Kirk Smith, Julia Jan.
20-22 RD Priorities Walsh Week 3A The Drug
Discovery David Ridley Jan. 27 Business Week
3B, Drug Development Jim McKerrow 4A Science
The Neglected Solomon Nwaka Jan. 29- Disease
Pipeline
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Roadmap
Lecture Topic Speaker Week Innovation
Economics SM, AK 4B 5B Feb. 5-12 Leading
Proposals Week 6A Price Discrimination and
Keith Maskus Feb. 17 Patent Pools Week
6B Financing Proposals Saul Walker Feb. 19 Week
7A Prizes Aidan Hollis
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Roadmap
Lecture Topic Speaker Week 7B Funding
Clinical Trials Dean Baker Feb. 26 Week
8A Advanced Market Michael Kremer Mar.
3 Commitments Mar. 6 Critical Evaluations
Due Week 9A Private Public Suerie Moon Mar.
10 Partnerships Week 9B Regulatory
Approval David Kessler
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Roadmap
Lecture Topic Speaker Week 10B Political
Economy Richard Wilder Mar. 17-19 James
Love Week 11-12 Incentive Design Choices SM,
Brian Wright, Mar. 31- Economists
Roundtable Suzanne Scotchmer Apr. 9 Week
13 Delivering Healthcare Julia Walsh Apr.
14-16 Ndola Prata Week 14 Student Papers
-- Apr. 20-21 Concluding Remarks
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Course Requirements
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Class Participation (25) Wiki (In Class
Discussion) Lecture Reporter
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(No Transcript)
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Midterm Project Critique an Existing Initiative
(25) Self-assemble
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Final Project White Paper (50) Groups of 4-6
students Ideal Self-assemble!
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Logistics Home Page http//gspp.berkeley.edu/ith
s/RDStrategies/Home.htm Wiki https//bspace.ber
keley.edu/portal