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Diabetes Mellitus Type 2

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Intensively treated patients received either insulin pump therapy or three or more injections of insulin daily. Adjustments in ... In type 2 diabetes, insulin ... – PowerPoint PPT presentation

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Title: Diabetes Mellitus Type 2


1
Diabetes Mellitus Type 2
  • Dr. Vinod Sanghi MD

2
Overview of Diagnosed and Undiagnosed Diabetes in
the United States2000
3
Diabetes in India
  • People with Diabetes 40 million
  • In 2025 About 70 million people with diabetes
  • DIABETES CAPITAL OF THE WORLD

4
Diabetes Major impact on Morbidity Mortality
  • Diabetes can lead to
  • Coronary heart disease
  • Diabetic retinopathy
  • Diabetic neuropathy
  • Diabetic nephropathy

5
Diabetes Prevalence, 1990-2001
6
Diabetes is increasing in India
Diabetes in India
  • Fast food
  • Lack of exercise

7
Estimated Costs of Diabetes in the United
States2002
8
Prevalence of Diabetes in the United States
According to Age and Sex2000
9
Estimated Prevalence of Diabetes in Global Adult
Population1995-2025
10
DCCT Effects of Intensive vs Conventional
Glycemic Control
11
UKPDS Design
12
UKPDS Effects of Intensive (Sulfonylurea/Insulin
) Treatment
13
UKPDS Effects of Intensive (Metformin)
Treatment
14
UKPDS Risk Reduction in Diabetes-Related
Complications (A1C)
15
UKPDS Effects of Tight vs Less-Tight Blood
Pressure Control
16
The 4S Diabetes Substudy
17
The CARE Trial Reduction of Coronary Events in
Subjects With and Without Diabetes
18
Evidence Supporting Multiple Risk Factor
Reduction
19
Multifactorial Intervention in Patients With Type
2 Diabetes Steno-2 StudyDesign
20
Multifactorial Intervention in Patients With
Type 2 Diabetes Steno-2 StudyTreatment Goals
21
Multifactorial Intervention in Patients With Type
2 Diabetes Steno-2 StudyCV Events
22
Pathophysiologyof Type 2 Diabetes andInsulin
Resistance
23
Insulin Resistance
24
Natural History of Type 2 Diabetes
25
Development of Type 2 Diabetes
26
Hyperglycemia in Type 2 Diabetes Results From
Three Major Metabolic Defects
27
Insulin Resistance Associated Conditions
28
Standards of Care forGlycemia, Lipids, and
Hypertension
29
2003 ADA Recommendations for Glycemic Control in
Type 2 Diabetes
30
2003 ADA Lipid Targets in Type 2 Diabetes
31
2003 ADA Treatment Recommendations for
Hypertension and Nephropathy
32
NCEP Diabetes as CHD Risk Equivalent
33
NCEP Metabolic Syndrome
34
NCEP Clinical Identification of the Metabolic
Syndrome
(Indian gt35in) (Indian gt30in)
35
Diabetes Prevention Program Reduction in
Diabetes Incidence
36
Diabetes Prevention Program Summary
37
AACE Guidelines for the Management of Type 2
Diabetes
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