Exploring the Structural Basis of Ligand-specific Activation and Antagonism of an AMPA Receptor - PowerPoint PPT Presentation

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Exploring the Structural Basis of Ligand-specific Activation and Antagonism of an AMPA Receptor

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(4) The 6-nitro moiety interacts with Y732, Y707 and a water molecule in the binding cleft. (5) The 7-nitro moiety is likely to hydrogen bond to OH of T686, and ... – PowerPoint PPT presentation

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