Health Effects of Soldering - PowerPoint PPT Presentation

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Health Effects of Soldering

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Antimony. Lead. Ben Franklin. Fetoprotection. Half-life in blood, one month; ... Antimony: numerous effects with uncertain dose-response including GI irritation ... – PowerPoint PPT presentation

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Title: Health Effects of Soldering


1
Health Effects of Soldering
  • W. Smith Chandler, MD, MPH, MS

2
Toxicology
  • All substances are poisons. There is none which
    is not a poison. The right dose distinguishes a
    poison from a remedy.
  • Paracelsus

3
Dose-Response
4
Low Dose Exposures
  • Subtle effects ignored
  • IQ
  • Personality
  • Reproductive
  • Latency periods complicate cause-effect
  • No evidence of an effect
  • ALARA

5
Solder
  • Lead
  • Cadmium
  • Tin
  • Bismuth
  • Silver
  • Antimony

6
Lead
  • Ben Franklin
  • Fetoprotection
  • Half-life in blood, one month bone, 27 years

7
Lead Levels
  • PbB units-micrograms/dl
  • 50-medical removal
  • 30-adult symptoms
  • 10-pediatric standard
  • JLab-all below 10
  • Marker for other exposures

8
Lead Toxicity
  • Can affect most organs
  • Developing nervous system has no clear NOEL for
    IQ
  • Adult nervous system
  • Psychological effects reduced memory slowed
    responses at PbB 20-40
  • Wrist and foot drop at higher levels

9
Lead Toxicity, cont.
  • Anemia
  • Reduced kidney function
  • Hypertension with no clear NOEL
  • Reproductive effects in both sexes
  • Reduced immune function
  • Studied at levels of 20-85
  • Increased colds flu reduced IgA

10
Cadmium
  • Itai Itai disease
  • Carcinogenic
  • Reduced brain function and intelligence
  • Irreversible kidney damage in solderers
  • Reduced lung function
  • Testicular damage in animal studies

11
Other Solder Metals
  • Tin overexposure to inorganic is stannosis
    involves lung irritation
  • Silver argyria, argyrosis, possible kidney
    effects
  • Antimony numerous effects with uncertain
    dose-response including GI irritation and
    possible cancer
  • Bismuth Pepto-bismol, tellurium breath

12
Flux and Defluxers
  • Terpenes taxol, menthol
  • Halogenated solvents CNS depression (anesthetic
    gases), liver kidney damage
  • Trichloroethylene
  • Trichloroethane (methyl chloroform)
  • Fluorides toothpaste
  • Chlorides irritants

13
Summary
  • Numerous important toxicants
  • Dose-response relationships are inconsistent
  • Long term effects are nebulous
  • Practice ALARA
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