Predicting Sustained Remission from Polysubstance Use: A three-year follow-up study Alexandre Laudet, Ph.D.1, and William White, M.A.2 1National Development and Research Institutes, Inc.; 2Chestnut Health Systems;

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Predicting Sustained Remission from Polysubstance
Use A three-year follow-up studyAlexandre
Laudet, Ph.D.1, and William White,
M.A.21National Development and Research
Institutes, Inc. 2Chestnut Health Systems
Descriptive of History and Predictor Domains by Subgoups Descriptive of History and Predictor Domains by Subgoups Descriptive of History and Predictor Domains by Subgoups Descriptive of History and Predictor Domains by Subgoups Descriptive of History and Predictor Domains by Subgoups Descriptive of History and Predictor Domains by Subgoups Descriptive of History and Predictor Domains by Subgoups Descriptive of History and Predictor Domains by Subgoups
BASELINE RECOVERY STAGE BASELINE RECOVERY STAGE BASELINE RECOVERY STAGE BASELINE RECOVERY STAGE BASELINE RECOVERY STAGE GENDER GENDER
Under 6 mo N 78 Under 6 mo N 78 6-18 m N75 18-36 m N56 3 yrs N76 Male N159 Female N126
BACKGROUND (REMISSION GRP DIF) BACKGROUND (REMISSION GRP DIF) BACKGROUND (REMISSION GRP DIF) BACKGROUND (REMISSION GRP DIF) BACKGROUND (REMISSION GRP DIF) BACKGROUND (REMISSION GRP DIF) BACKGROUND (REMISSION GRP DIF) BACKGROUND (REMISSION GRP DIF)
BL abstinence in months 3.2 11.2 11.2 27.0 84.5 33.1 29.8
Previous attempt ( yes) 85.7 74.7 74.7 58.9 52.6 68.6 68.8
Lifetime severity 11.8 11.6 11.6 11.8 11.8 11.7 11.7
Ever treatment at intake 88.5 88.0 88.0 80.4 82.9 81.8 89.7
Ever 12-step at intake 85.9 90.7 90.7 96.4 86.8 88.1 91.3
INTRAPERSONAL RESOURCES INTRAPERSONAL RESOURCES INTRAPERSONAL RESOURCES INTRAPERSONAL RESOURCES INTRAPERSONAL RESOURCES INTRAPERSONAL RESOURCES INTRAPERSONAL RESOURCES INTRAPERSONAL RESOURCES
Motivation 3.1 3.2 3.2 3.1 3.2 3.1 3.2
Self-efficacy 2.9 3.0 3.0 3.0 3.0 3.0 3.0
Addiction chronic 3.2 3.4 3.4 3.4 3.4 3.3 3.4
Spirituality 3.2 3.3 3.3 3.2 3.2 3.1 3.3
Life Meaning and purpose 2.8 3.0 3.0 2.8 3.0 3.0 3.0
Religiosity 4.8 5.1 5.1 5.2 5.4 4.9 5.4
INTERPERSONAL RESOURCES INTERPERSONAL RESOURCES INTERPERSONAL RESOURCES INTERPERSONAL RESOURCES INTERPERSONAL RESOURCES INTERPERSONAL RESOURCES INTERPERSONAL RESOURCES INTERPERSONAL RESOURCES
General Social Support 2.9 3.0 3.0 3.2 3.1 3.1 3.1
Continuous 12-step (yes) 14.9 34.7 34.7 44.4 38.2 31.8 32.8
12-step involvement 3.4 4.4 4.4 5.1 4.5 4.1 4.5
Treatment during study () 43.8 30.0 30.0 21.6 9.3 29.3 23.0
plt.05 plt.01 plt.001 plt.05 plt.01 plt.001 plt.05 plt.01 plt.001 plt.05 plt.01 plt.001 plt.05 plt.01 plt.001 plt.05 plt.01 plt.001 plt.05 plt.01 plt.001 plt.05 plt.01 plt.001
Baseline Characteristics (N285) Baseline Characteristics (N285)
Men 55.8
Age (mean, SD) 43.5 (8.1)
Race/ethny African American Caucasian Mixed/other 63.6 15.9 20.5
Hispanic origin 17.2
Primary income Job on/off the books Govt. assistance Other legitimate income 35.7 59.9 5.2
HIV 23.4
Hep C 30.8
Psychiatric disorder (ever) 39.9
Primary Substance Primary Substance
Crack 59.6
Heroin 17.4
Cocaine 9.9
Alcohol 7.8
Other 5.3
Generally Long and Severe History of Polysubstance Use
Years regular use of drugs, Mean 18.7 (St. Dev 12.0)
Drug abstinence duration _at_ intake Mdn 15.6 months
Summary of Bivariate Findings

• All predictor domains significantly correlated
  with outcome (plt.05) except self-efficacy.
• When baseline remission duration was held
  constant, social support, spirituality and life
  meaning lost statistical significance.
• The remaining domains were entered as predictors
  in logistic regressions.

SIGNIFICANT PREDICTORS of SUSTAINED REMISSION for 3 YEARS by BASELINE REMISSION STAGE and GENDER Odds Ratio (all Plt.05 or Smaller) SIGNIFICANT PREDICTORS of SUSTAINED REMISSION for 3 YEARS by BASELINE REMISSION STAGE and GENDER Odds Ratio (all Plt.05 or Smaller) SIGNIFICANT PREDICTORS of SUSTAINED REMISSION for 3 YEARS by BASELINE REMISSION STAGE and GENDER Odds Ratio (all Plt.05 or Smaller) SIGNIFICANT PREDICTORS of SUSTAINED REMISSION for 3 YEARS by BASELINE REMISSION STAGE and GENDER Odds Ratio (all Plt.05 or Smaller) SIGNIFICANT PREDICTORS of SUSTAINED REMISSION for 3 YEARS by BASELINE REMISSION STAGE and GENDER Odds Ratio (all Plt.05 or Smaller) SIGNIFICANT PREDICTORS of SUSTAINED REMISSION for 3 YEARS by BASELINE REMISSION STAGE and GENDER Odds Ratio (all Plt.05 or Smaller) SIGNIFICANT PREDICTORS of SUSTAINED REMISSION for 3 YEARS by BASELINE REMISSION STAGE and GENDER Odds Ratio (all Plt.05 or Smaller)
BASELINE RECOVERY STAGE BASELINE RECOVERY STAGE BASELINE RECOVERY STAGE BASELINE RECOVERY STAGE GENDER GENDER
Under 6 mo N 78 6-18 mo N75 18-36 mo N56 3 yrs N76 Male N159 Female N126
BL length of abstinence 1.6 1.4 1.2 1.0 1.0 1.0
Continuous 12-step _at_F3 2.8 3.5 2.0 3.7 5.1 2.9

• Funded by National Institutes on Drug Abuse Grant
  R01 DA14409 and by the Peter McManus Charitable
  Trust
• The authors have no financial relationships that
  related to the topic of this presentation.
• Correspondence laudet_at_ndri.org