Opportunities for Collaboration

1
Opportunities for Collaboration

• Presentation to Visiting Team from
• Sandia National Laboratory
• Meeting Held at UCSD
• La Jolla, CA
• April 16, 2001

2
Governor Davis Created New Institutes for
Science, Innovation, and Tech Transfer
The California Institute for Bioengineering,
Biotechnology, and Quantitative Biomedical
Research
The Center for Information Technology Research
in the Interest of Society (Proposed-UCB, UCD,
UCSC, UCM)
UCB
The California NanoSystems Institute
UCSF
UCSC
The California Institute for Telecommunications
and Information Technology
3
The Next Wave of the Internet Will Extend IP
Throughout the Physical World
This is the Research Context for the California
Institute for Telecommunications and Information
Technology
Materials and Devices Team, UCSD
4
The Institute is Built on Existing UCSD/UCI
Faculty Strengths
Center for Wireless Communications
Broadband Wireless
ANTENNAS AND PROPAGATION
LOW-POWERED CIRCUITRY
COMMUNICATION THEORY
COMMUNICATION NETWORKS
MULTIMEDIA APPLICATIONS
Architecture Media Access Scheduling End-to-End
QoS Hand-Off
Changing Environment Protocols Multi-Resolution
RF Mixed A/D ASIC Materials
Modulation Channel Coding Multiple
Access Compression
Smart Antennas Adaptive Arrays
Source UCSD CWC
5
San Diego Supercomputer Center
Cal(IT)2 Research Infrastructure Partner

• Areas of Strength Leadership for Initial
  Interactions between
  Cal(IT)2 and

Phil Papadopoulos
Clusters
Networking and Wireless
Phil Papadopoulos, Frank Dwyer, Ronn Ritke, kc
claffy, Hans-Werner Braun
Chaitan Baru, Reagan Moore, Tony Fountain
Data Mining/Metadata/AI
Enviroinformatics/Observing Systems
Alison Withey
Mike Bailey, John Moreland
Visualization/GIS/Augmented Reality
Jay Boisseau, Mary Thomas, Allan Snavely
Computing and Portals
Mike Vildibill, Frank Dwyer, Phil Andrews, Phil P.
Core IT Infrastructure and Integration
Tom Perrine
Computer Security Infrastructure
Ann Redelfs, Kim Baldridge, Theresa Boisseau
Education/Outreach
John Wooley, Phil Bourne, Shankar Subramaniam,
Mark Ellisman, Mike Gribskov, Kim Baldridge
Bioinformatics/Digitally Enabled Med./ Comp.
Chemistry/Biology
Peter Arzberger, Anke Kamrath, Phil Papadopoulos,
Chaitan Baru, Alison Withey
Management
6
Complex Problems Require a New Research and
Education Framework
220 UCSD UCI Faculty Working in
Multidisciplinary Teams With Students, Industry,
and the Community
The State Provides 100 M For New Buildings and
Equipment
www.calit2.net
7
The UCSD Cal-(IT)2 BuildingPreliminary Design
Occupancy 2004 220,000 Gross SF

• New Media Arts Spaces
• Research Lab
• Visualization Labs
• Audiovisual Editing Facilities
• Gallery Space
• Helping Design Auditorium

8
A Broad Partnership Response from the Private
Sector

• Akamai
• Boeing
• Broadcom
• AMCC
• CAIMIS
• Compaq
• Conexant
• Copper Mountain
• Emulex
• Enterprise Partners VC
• Entropia
• Ericsson
• Global Photon
• IBM
• IdeaEdge Ventures
• Intersil
• Irvine Sensors
• Leap Wireless
• Litton Industries

• Mission Ventures
• NCR
• Newport Corporation
• Orincon
• Panoram Technologies
• Printronix
• QUALCOMM
• Quantum
• R.W. Johnson Pharmaceutical RI
• SAIC
• SciFrame
• Seagate Storage
• Silicon Wave
• Sony
• STMicroelectronics
• Sun Microsystems
• TeraBurst Networks
• Texas Instruments
• UCSD Healthcare

Computers Communications Software Sensors Biomedic
al Startups Venture Firms
Large Partners gt10M Over 4 Years
140 M Match From Industry
9
Elements of the Cal -(IT)2 Industrial
Partnerships

• Endowed Chairs for Professors
• Start-Up Support for Young Faculty
• Graduate Student Fellowships
• Research and Academic Professionals
• Sponsored Research Programs
• Equipment Donations for Cal-(IT)2 and Campus
• Named Laboratories in new Institute Buildings
• Pro Bono Services and Software

10
The Southern High Tech CoastIs Well Organized
for Partnering

• From Bandwidth Bay to Wireless Valley
• 70,000 Fiber Strand-Miles Under Downtown SD
• Nations Center for Wireless Companies
• San Diego Telecom Council
• www.sdtelecomcouncil.org
• 200 Member Companies
• SIGs on Optical, Wireless, Satellite, etc.
• UCSD CONNECT
• www.connect.org
• UCSD Program in Technology and Entrepreneurship
• Many Others
• BIOCOM
• Mayors Science and Technology Commission
• UCI Chief Executive Roundtable

11
Near Term GoalBuild an International Lambda Grid

• Establish PACI High Performance Network
• SDSC to NCSA to PSC LambdaNet
• Link to
• State Dark Fiber
• Metropolitan Optical Switched Networks
• Campus Optical Grids
• International Optical Research Networks
• NSF Fund Missing Dark Fiber Links For
• Scientific Applications
• Network Research

12
Nanotechnology Is Becoming Essential for
Photonics
Source UCSD Ultrafast and Nanoscale Optics
Group, Shaya Fainman
13
The UCSD Living Grid LaboratoryFiber,
Wireless, Compute, Data, Software
Source Phil Papadopoulos, SDSC
14
Broadband Wireless Internet is Here Today

• Create Wireless Internet Watering Holes
• Ad Hoc IEEE 802.11 Domains
• Real Broadband--11 mbps Going to 54 mbps
• Home, Neighborhoods, Office
• MobileStar--Admiral Clubs, Major Hotels,
  Restaurants,
• UCSDKey Campus Buildings, Dorms, Coffee Shops
• Upsides
• Ease of Use
• Unlicensed so Anyone can Be a Wireless ISP
• Will Accelerate InnovationLiving in the Future
• Downsides
• Not Secure
• Shared Bandwidth
• Short Range Coverage

The future is already here, its just not evenly
distributedWilliam Gibson, Author of
Neuromancer
15
Web Interface to Grid ComputingThe NPACI
GridPort Architecture
802.11b Wireless

• Interactive Access to
• State of Computer
• Job Status
• Application Codes

16
Cal -(IT)2 Researchers Will Focus on
Semiconductor System Chips

• Two Trends
• Increasing Use of Embedded Intelligence
• Networking of Embedded Intelligence
• In Ten Years
• The Big eg., Terabit Optical Core, Gigabit
  Wireless, ...
• The Small eg., Pervasive Self-powered Sensor
  Motes
• The Cheap eg., One-Cent Radios
• Short-range (10-100m), Low Power (10nJ/bit), Low
  Bit Rate (1-100kbps)
• The Consequence
• Smart Spaces, Intelligent Interfaces, Ad Hoc
  Networks

Source Rajesh Gupta, UCI Center for Embedded
Computer Systems
17
Goal Design of Configurable Wireless Embedded
Sensing/Computing/Communicating Appliances
Source Sujit Dey, UCSD ECE
18
The Wireless Internet will Transform
Computational Science and Engineering

• Teraflop Supercomputers Simulate in Dynamic 3D
• Evolving a System Requires Knowing the Initial
  State
• Add Wireless Sensors and Embedded Processors
• Give Detailed State Information
• Allows for Comparison of Simulation with Reality
• Critical Software Research Required
• Security
• Robust Scalable Middleware
• Effervescent Architectures
• Mobile Code
• Resource Discovery
• Ad Hoc Networking
• SensorNet Simulations

19
The High PerformanceWireless Research and
Education Network
NSF Funded PI, Hans-Werner Braun, SDSC Co-PI,
Frank Vernon, SIO 45mbps Duplex Backbone
http//hpwren.ucsd.edu/Presentations/HPWREN
20
Wireless Antennas Anchor Network High Speed
Backbone
http//hpwren.ucsd.edu/Presentations/HPWREN
Source Hans-Werner Braun, SDSC
21
The Wireless Internet Adds Bio-Chemical-Physical
Sensors to the Grid

• From Experiments to Wireless Infrastructure
• Scripps Institution of Oceanography
• San Diego Supercomputer Center
• Cal-(IT)2
• Building on Pioneering Work of Hans-Werner Braun
  Frank Vernon

Source John Orcutt, SIO
22
The Wireless Internet Will Improve the Safety of
Californias 25,000 Bridges
New Bay Bridge Tower with Lateral Shear Links
Cal-(IT)2 Will Develop and Install Wireless
Sensor Arrays Linked to Crisis Management
Control Rooms
Source UCSD Structural Engineering Dept.
23
Can Use of These Technologies Help Us Avoid the
Downsides of Prolonged Growth?

• Add Wireless Sensor Array
• Build GIS Data
• Focus on
• Pollution
• Water Cycle
• Earthquakes
• Bridges
• Traffic
• Policy
• Work with the Community to Adapt to Growth

UCI
Huntington Beach
High Tech Coast
UCSD
Mission Bay
San Diego Bay
24
High Resolution Data Analysis FacilityLinked by
Optical Networks to PACI TeraGrid
Panoram Technologies, SGI, Sun, TeraBurst
Networks, Cox Communications, Global
Photon Institute Industrial Partners
Planned for Fall 2001 at SIO Support from SDSC
and SDSU
25
From Telephone Conference Calls to Access Grid
International Video Meetings
Creating a Virtual Global Research Lab
Access Grid Lead-Argonne NSF STARTAP Lead-UICs
Elec. Vis. Lab
26
Bridging Internet Data Collection and
Theoretical Scaling Analysis

• Network Graph Theory
• Sparse
• Clustered
• Hierarchical
• Power Laws
• Goal
• IT First Principles
• Quantitative Laws
• Verify Against Reality
• Use for Optimal Design

100,000 nodes Colored by Node IP Address Bill
Cheswick, Lucent Bell Labs and Hal Burch, CMU
Fan Chung Graham, UCSD
www.caida.org/projects/internetatlas/gallery/
27
Possible Multiple Qubit Quantum Computer

• SEM picture of posts fabricated at the Cornell
  Nanofabrication Facility
• PI John Goodkind (UCSD Physics) Roberto
  Panepucci of the CNF
• Electrons Floating over Liquid He
• One Electron per Gold Post

NSF ITR PROGRAM CASE WESTERN RESERVE
UNIVERSITY/ UCSD/MICHIGAN STATE
28
The Institute Facilitates Faculty Teams to
Compete for Large Federal Grants
Proposal-Form a National Scale Testbed for
Federating Multi-scale Brain Databases Using NIH
High Field NMR Centers
Surface Web
Deep Web
Source Mark Ellisman, UCSD
29
Why Not Constantly Compute on Federated
Repositories?

• Currently
• Instrument Coordinates
• Virtual Human NLM Project
• Transformations to Organ Coordinates
• Surgical View of Body
• Define Differences in Organs
• Eg. UCLA Human Brain Mapping ProjectArt Toga
• Fly Through Organs
• Virtual Colonoscopy (www.vitalimaging.com)
• Future
• Train AI Software on
• Millions of Human Image DataSets
• Define Distribution Functions
• Thresholds for Medical Attention
• Life Cycle of Single Individuals
• Automatic Early Warnings

30
As Our Bodies Move On-LineBioengineering and
Bioinformatics Merge

• New SensorsIsraeli Video Pill
• Battery, Light, Video Camera
• Images Stored on Hip Device
• Next StepPutting You On-Line!
• Key Metabolic and Physical Variables
• Wireless Internet Transmission
• Model -- Dozens of 25 Processors and 60 Sensors /
  Actuators Inside of our Cars
• Post-Genomic Individualized Medicine
• Combine Your Genetic Code Imaging, with Your
  Bodys Data Flow
• Use Powerful AI Data Mining Techniques

www.givenimaging.com
31
What Data is Needed to Specify a Single
Eukaryotic Cell?

• Organelles
• 4 Million Ribosomes
• 30,000 Proteasomes
• Dozens of Mitochondria
• Macromolecules
• 5 Billion Proteins
• 5,000 to 10,000 different species
• 1 meter of DNA with Several Billion bases
• 60 Million tRNAs
• 700,000 mRNAs
• Chemical Pathways
• Vast numbers
• Tightly coupled
• Is a Virtual Cell Possible?

www.people.virginia.edu/rjh9u/cell1.html
32
Cellular Signaling Pathway Database, Analysis
Tools and User Interface
Alliance for Cell Signaling PI Alfred Gilman,
UT-SW MED UCSF, Caltech, Stanford, UCSD NIH and
Industrial Funding
Shankar Subramaniam, UCSD, Director, Data
Coordination Bioinformatics Lab, Alliance for
Cell Signaling
33
Monte Carlo Cellular Microphysiology From IBM
Blue Horizon to the Grid

• PROJECT LEADERS
• Francine D. Berman
• UC San Diego
• Terrence J. Sejnowski
• Salk Institute for Biological Studies
• PARTICIPANTS
• Dorian ArnoldJack DongarraRichard Wolski
• University of Tennessee
• Thomas M. BartolLin-Wei Wu
• Salk Institute for Biological Studies
• Henri CasanovaMark H. EllismanMaryann Martone
• UC San Diego

Rendered by Tom Bartol of the Salk Institute for
Biological Studies Joel Stiles of Cornell
University using Pixar PhotoRealistic RenderMan

• Neurotransmitter Activity
• Leading to Muscle Contraction
• MCell Simulated
• The Transmission of 6,000 Molecules of the
  Neurotransmitter Acetylcholine (Cyan Specks)
• In a Reconstructed Mouse Sternomastoid
  Neuromuscular Junction
• Containing Acetylcholinesterase (White
  Spheres).

www.npaci.edu/envision/v16.4/mcell.html
34
The Institute Will Focus on the Use of Highly
Parallel and Distributed Systems

• PACI Distributed Terascale Linux Clusters
• Multi-Teraflop
• Thousands of Processors
• High Performance Grids
• Lambda Connected
• Heterogeneous Compute and Storage
• DoE Labs
• Highest End Machines
• Experimental Architectures (Blue Light)
• Peer-to-Peer Computing
• Millions of Processors
• NT/Intel Homogenous PCs

35
The Drive toward Commodity Processorsin Parallel
Computing
Changes in Architecture Induce Changes in
Algorithms
Internet Computing
Intel Processors
36
Entropias Planetary Computer Grew to a Teraflop
in Only Two Years
The Great Mersenne Prime (2P-1) Search
(GIMPS) Found the First Million Digit
Prime www.entropia.com
Eight 1000p IBM Blue Horizons
Deployed in Over 80 Countries
37
SETI_at_home Demonstrated that PC Internet Computing
Could Grow to Megacomputers

• Running on 500,000 PCs, 1000 CPU Years per Day
• Over Half a Million CPU Years so far!
• 22 Teraflops sustained 24x7
• Sophisticated Data Signal Processing Analysis
• Distributes Datasets from Arecibo Radio Telescope

Arecibo Radio Telescope
Next Step- Allen Telescope Array
38
Extending the Grid to Planetary Dimensions Using
Distributed Computing and Storage
AutoDock Application Software Has Been Downloaded
to Over 20,000 PCs Nearly 3 Million CPU-Hours
Computed
In Silico Drug Design
Art Olson, TSRI
39
From Software as Engineering to Software as
Biology

• Stanford Professor John Koza
• Uses Genetic Programming to Create a Working
  Computer Program From a High-Level Problem
  Statement of a Problem
• Starting With a Primordial Ooze of Thousands of
  Randomly Created Computer Programs, a Population
  of Programs Is Progressively Evolved Over a
  Series of Generations
• Has Produced 21 Human-Competitive Results

1,000-Pentium Beowulf-Style Cluster Computer for
Genetic Programming
www.genetic-programming.com/
40
A Mobile Internet Powered by a Planetary Scale
Computer