Using Labs to Manage Your Childs Biomedical Program and Interpret the Results

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Using Labs to Manage Your Childs Biomedical
Program and Interpret the Results

• Tracy Ziemann PA-C
• Sonja Hintz RN
• True Health Medical Center
• Naperville, IL

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Goals for this Presentation

• Basic Laboratory Tests your general practitioner
  can order
• How do the lab findings present in my childs
  behavior
• Potential treatment options available for
  abnormal results

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Build your foundation

• Create your own History and Physical some- times
  a time line is helpful
• Review your
• Environment Home, School and other places, what
  triggers are there
• Diet texture, food choices, when your child eats
• Elimination Are your Childs stool frequent, or
  infrequent, what color and odor do they have?

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Gathering information

• When a doctor sees an autistic child there is a
  need for the parent to relay the child's physical
  condition
• In the biomedical treatment of autism we look at
  behaviors and the physical condition of the child
  to place them in category

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Basic initial testing

• Blood
• CBC, CMP
• TSH, Free T4
• Iron, Ferritin
• Lead, blood
• Copper (serum), Zinc (plasma)
• Ammonia, blood (Has to be sent Frozen)
• Immune system evaluation IgG total and 4
  subclasses, IgA and 2 subclasses, total IgE and
  IgM

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Additional Blood Tests

• Viral Titers QUANTITATVE IgG
• CMV
• EBV
• HHV6
• HSV
• Varicella
• Measles
• Mumps
• Rubella
• Hep. B surface Ab
• Polio

• Strep Titers
• ASO titer quantitative
• AntiDNASE B Ab quantitative
• Mitochondrial Tests
• Blood Amino Acids
• Carnitine Panel
• Lactic Acid
• Pyruvate Acid

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Viruses

• Physical Presentation
• Never sick
• Always sick
• Regression after illness
• Poor eye contact
• Improved eye contact with a fever
• Stimmy Behavior
• Hand flapping
• Sideways glancing
• Finger flicking

• Treatments
• Olive leaf extract
• Elderberry
• Oil of Oregano
• Herbs/Nutrients that support the immune system
• Antiviral medications Valtrex
• High dose Vitamin A
• Homeopathy
• Enzymes

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Strep

• Physical Presentation
• Poor eating
• Clearing the throat
• Swollen lymph glands
• Obsessive thoughts/behavior
• Seizures
• Tics
• Someone else in the family has strep

• Treatments
• Biofilm treatment esp if strep is found in the
  stool
• Antibiotics Zithromax
• Probiodics
• Immune supportive agents IVIG
• Berberine
• Golden Seal
• Oregon grape root

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GI Health Markers

• Stool testing
• CDSA
• CPP x3
• Microbiology
• Urine organic acid test (OAT)
• Great Plains lab- OAT
• Metabolic Analysis Profile (MAP) Genova
  diagnostics

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Yeast symptoms

• Giggly, inappropriate laughing
• Foggy, spacey
• Change in bowel movements (foul/yeasty smelling
  stools), gas, and bloated belly
• Yeasty rash/diaper rash, white coating on tongue,
  red ring around the anus, ringworm, cradle cap
• Bedwetting or accidents
• Sleep disturbance or Night waking
• Hyperactivity, hand flapping, toe walking
• Sugar craving

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Treatment

• Start a potent Probiotic
• Digestive Enzymes
• Clean up the diet
• Casein/Gluten free
• Limit sugar
• Consider SCD and/or Low oxalate
• Support the gut and reduce inflammation
• Vitamins/supplements, herbs, medications

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More Treatment options

• Antifungals
• Drugs
• Nystatin, Ampho B
• Fluconazole
• Itraconazole
• Ketoconazole
• Herbals
• Berberine
• Grapefruit Seed Extract
• Oil of Oregano, Pau dArco
• Garlic, Samento
• Homeopathy

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Look OUT for Die Off

• Loose stools, diarrhea
• Behavior, irritability
• Head aches, head banging
• Fatigue
• Sleep disturbance
• Rashes

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Parasites

• What may keep you and your child up at night

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Signs and Symptoms of Parasites

• Discomfort and bloating of stomach
• Itchy buttocks, night waking, fecal smearing
• Diarrhea and constipation
• Teeth grinding
• Mal absorption of nutrients, pica, insatiable
  appetite
• Allergies
• Behavior changes and/or aggression, worse at full
  moon
• Picking
• Biting
• Restlessness

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Treatment for Parasites

• Probiotics
• Herbs
• Wormwood
• Black walnut
• Pumpkin seeds
• Clove
• Coconut oil
• Homeopathy
• Antiparasitic medications
• Metronidazole
• Paromomycin

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• They dont go down without a fight!!

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Potential reactions when eliminating these
pathogens

• Symptoms
• Irritability, aggression, behavioral issues
• Increased stimming, hyperactivity, sleeplessness
• Skin rash, diaper rash, fever
• Possible Causes
• Side effect of supplement or allergy to drug
• Yeast or Bacterial Flare-up (Balancing act)
• Detox Reaction Too rapid of an effect leading
  to vitamin or mineral deficiency, oxidative
  stress, liver or kidney stress
• Die off Rapid death of gut bugs, leading to
  excess release of toxins and subsequent liver or
  kidney stress

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Treatment Approach

• Rate severity, if severe stop supplement, notify
  physician
• Treat with Activated charcoal/Bentonite clay
  and/or Alka Seltzer Gold, homeopathic remedy, if
  helpful probably die off
• Rule out dysbiosis, treat accordingly
• Check ammonia level
• Add Liver Support
• Milk thistle, artichoke extract, dandelion root
• Give at bedtime

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• Clostridia produce toxins and enzymes that
  create severe gut inflammation and produce watery
  diarrhea

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Clostridia issues

• Treatment
• Probiotics, High Potency single strain
• Sacchyromyces Boulardii
• Antibiotics
• Vancomycin
• Metronidazole (Flagyl)
• Immune modulators
• Homeopathics
• HBOT

• Symptoms
• Aggressive
• Temper
• Agitation
• Irritable
• Very foul stools
• Mucus in stools
• Severe diarrhea following antibiotic use

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Evaluation of Heavy Metal Toxicity

• Provocative Testing is often unconvincing in ASD
  due to impaired detoxification.
• Urine Toxics, Fecal Toxics, and Hair Analysis
  show excretion of toxic metals. We have no way
  to determine total body burden.
• RBC Blood testing is a poor measure of chronic
  heavy metal burden. However, blood may show acute
  exposure.
• There are no standards for diagnosing chronic
  toxicity.
• There are no tests to determine body burden of
  metals.
• Lead is a bone seeker and can only be measured in
  blood 12 hrs after exposure, therefore blood Pb
  is not an adequate indicator of low level chronic
  toxicity.
• Mercury has an affinity for fatty tissue and a
  developing brain, and is very rarely seen in
  blood.
• Urinary porphyrin testing promising.

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Benefits of Chelation

• Better sleep
• Cognitive gains
• Better speech and language
• Improved eye contact
• Fine and gross motor improvement
• Better focus, attention, awareness

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• IMPORTANT to continue to monitor symptoms.
• Labs can only help point us in the right
  direction.

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Have courage and follow your own path.
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Thank You and Good Luck on your Journey