Chapter 11 Cell Signaling - PowerPoint PPT Presentation

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Chapter 11 Cell Signaling

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Catalysis (turn on an enzyme - glycogen phosphorylase) Ion transport ... Adenyl Cyclase. Pathways relay signals from receptors to cellular responses. Protein kinase ... – PowerPoint PPT presentation

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Title: Chapter 11 Cell Signaling


1
Chapter 11 - Cell Signaling
2
Cell Signaling
  • Cell signaling in yeast
  • Types of signaling
  • Overview of signaling pathways
  • Reception, transduction and response
  • G-protein linked pathways - epinepherine
  • Activation of protein synthesis

3
Yeast cells recognize mating types.
4
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5
Types of Signaling
  • Local
  • Paracrine
  • Synaptic
  • Long distance
  • Hormonal

6
Paracrine Signalling
7
Synaptic Signaling
8
Hormonal Signaling
9
Overview
10
Three Stages
  • Reception
  • Transduction
  • Response

11
Reception
  • Signal molecule binds to external portion of the
    receptor.
  • A conformational change occurs
  • Processes are activated inside the cell.

12
Transduction
  • Communicates the receptor signal to the cellular
    response
  • Usually several steps
  • Amplifies the signal

13
Cellular Responses
  • Catalysis (turn on an enzyme - glycogen
    phosphorylase)
  • Ion transport
  • Rearrangement of the cytoskeleton
  • Synthesis of new proteins

14
Signal Transduction
15
G Proteins
  • Yeast mating factors
  • Hormone responses - epinepherine
  • Neurotransmitters
  • Vision
  • Smell

16
G Proteins
17
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18
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19
A Receptor
20
Adenyl Cyclase
21
Pathways relay signals from receptors to cellular
responses.
Protein kinase enzyme that phosphorylates a
protein.
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