FROM TYMPANIC RETRACTION POCKET TO CHOLESTEATOMA - PowerPoint PPT Presentation

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FROM TYMPANIC RETRACTION POCKET TO CHOLESTEATOMA

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FROM TYMPANIC RETRACTION POCKET TO CHOLESTEATOMA ... Myringomalacia , collapsed eardrum. Retraction pocket. ATELECTASIA. ADHESIVE OTITIS. WRONG SKIN ... – PowerPoint PPT presentation

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Title: FROM TYMPANIC RETRACTION POCKET TO CHOLESTEATOMA


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FROM TYMPANIC RETRACTION POCKET TO CHOLESTEATOMA
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Classifications of retraction pockets
  • SADE (4, atelectasia, metula)
  • ARS (3, stable, instable)
  • CHARACHON (3, mobile, fixed)
  • TOS (4, papillar)
  • GERSDORFF (6, controlable, endos)
  • MARTIN (location, type, ossicle)
  • DORNHOFFER (4, chole.)
  • LIVI (2, safe, unsafe)
  • BLACK (4, ossicle, chole)

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DRUM COLLAPSE ONTO THE PROMONTORIUM
  • Pars tensa retraction pocket stage IV
  • Middle ear Atelectasis
  • Adhesive Otitis
  • Cholesteatoma by retraction pocket
  • Mesotympanum Cholesteatoma
  •  Epidermose du fond de caisse 

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?
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PRE-CHOLESTEATOMA
  • Unsafe retraction pocket

marginal
keratine debris
Bony contact or adhesiveness
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?
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OTOSCOPIC CLASSIFICATION
  • NON Marginal retraction
    pocket
  • Marginal /- fixed invagination
    pocket, control, tube
  • Hyperkeratosis epith.
    précholesteatoma, surgery
  • Extend /- osseous lysis cholesteatoma

SKIN IN A WRONG PLACE
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migration
retraction
proliferation
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my
Myringomalacia , collapsed eardrum Retraction
pocket
ATELECTASIA ADHESIVE OTITIS
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WRONG SKIN
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IMMUNE RESPONSE
Lymphocyte T
Langerhanscell
 immunological sentinels 
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Cholesteatomaa defective wound healing
  • EGF-EGFR
  • Autocrine hyperactivity
  • keratinization
  • proliferation
  • chemiotaxis
  • wound healing

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LOSS OF GROWTH CONTROL
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The pathogenesis of cholesteatoma does not only
depend on the middle ear, but also very probably
on the immunological status of the external
auditory bottom skin cells, which have an
unique laminar migratory potential.
The transformation of a retraction pocket into a
true precholesteatoma is an active phenomenon
with an intrinsic dysfunction of the external
auditory canal bottom skin immune system.
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Tympan
  • Absence de 3 couches Perforation
  • Absence de 3 coucheset proliferation epiderme
    Cholesteatom
  • Absence de 2 couches LP et muq Poche de
    retraction
  • Absence de 2 couches LP et muq et proliferation
    epiderme - Cholesteatome

Non marginal Marginal
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Les origins
  • 1683 Du Verney steatoma
  • 1829 Cruveilhier tumeur perlée
  • 1830 Muller cholésteatoma cholestrine,
    graisse, tumeur

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Le moyen age Cholesteatoma - Osteite
  • Cholesteatome / Mastoide (Wiitmack, Diamant)
  • Essais de redefinition
  • Keratom, Margaritom, Cholesteatose (Young),
    épidermose (Toumarkin), cholesteatose desquamante
    (Birrel, Ruedi),keratose obstructive (Biber),
    epidermose desquamante (Mac Guckin)

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1990 Iere actuelle Definition
  • Presence dun epithelium malphigien kératinisant
    dans les cavités tympaniques (avec accumulation
    de squames)
  • Pseudo-tumeur inflammatoire de type épidermique
    présentant un double potentiel de desquamation et
    de dérosion (Susceptible de récidive)
  • Presence de peau dans loreille moyenne avec
    accumulation de kératine formant une véritable
    tumeur bénigne

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1990 Iere actuelle Definition
  • Poche de rétraction
  • Poche dinvagination
  • Pré-cholesteatome
  • (wrong) skin in the wrong place

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De la poche de rétractione au cholesteatome
  • Le tympan est la façade de lotite chroniqie
  • Cholesteatome résiduel Améliorer la chirurgie
    dexérése
  • La récidive du cholesteatome Améliorer la
    chirurgie réparatrice

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