CTSA Consortium Oversight Committee Meeting

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CTSA Consortium OversightCommittee Meeting
John I. Gallin, M.D. October 3, 2007
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Opportunities at the NIH Clinical Center

• Can the NIH Clinical Center be a resource to
  enrich the CTSA network?
• CTSA network certainly can enrich the Clinical
  Center.

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CC Resources

• Patients with rare diseases
• Phenotyping
• Imaging
• Metabolic units
• Biomechanics lab
• Unique products
• Blood products
• PET ligands
• GMP facility to make candidate drugs

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Current Opportunities

• Testing site for new clinical research tools
• Patient surveys
• Simple informed consent forms
• Informatics tools (ProtoType, Data repository,
  Bio-repository)
• Training
• Investigators, administrative managers, nurses
  (exposure to NIH, FDA, OHRP, CMS)

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Future Opportunities
Exchange/sabbaticals for clinical
researchers Bench to Bedside Awards
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NIH Bench-to-Bedside Program

• Established 1999 to
• Foster collaboration between intramural clinical
  and basic scientists

• 119 awards 400 applications
• 24M awarded

2006 initiated intramural/extramural pilot
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Extramural Partners

• Mass General
• Univ of MD
• Tulane Univ
• Univ of Miami
• Univ of OK
• Univ of Wisc
• MedImmune
• Makere Univ
• Cleveland Clinic
• Univ of Toronto
• Drexel Univ
• Mayo Clinic
• Univ of WA
• Univ of Oxford, UK

• Childrens National Medical Center
• Oregon State University
• St. Michaels Medical Center
• Karmanos Cancer Ctr/Wayne State Univ
• MD Anderson Cancer Center (Univ of TX)
• Washington Hospital Center
• Fred Hutchinson Cancer Research Ctr
• Gynecologic Oncology Group
• Hackensack Univ Med Ctr
• George Washington Univ
• Memorial Sloan Kettering
• ABUTH, Zaria, Nigeria
• Kennedy Krieger Institute

• USC
• NNMC
• WRAMC
• UVA
• UCSF
• UPenn
• UCLA
• USUHS
• Harvard
• Dartmouth
• JHU
• Univ of IL
• Georgetown
• Med Coll of VA

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Future Opportunities
Exchange/sabbaticals for clinical
researchers-Bench to Bedside Awards Participate
in multi center studies Provide specialized
phenotyping for select multi-center
studies Serve as reference lab for difficult lab
testing Facilitate interactions with other govt
agencies
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Other Opportunities?
How can the Clinical Center enrich the CTSA
network?