Chromosomal replication is bidirectional

1
Chromosomal replication is bidirectional
The structure of the bacterial Chromosome
Cairns (1963) and Rodriguez (1973) Autoradiography
- 3H labeled DNA
2
The structure of the bacterial Chromosome
Growing cells showing Geimsa stained
condensed chromosome
Lysed E.coli cell (lysozyme)
3
DNA Topology
Uncoiled DNA
Bacterial Cell
Negatively supercoiled DNA
RNA CORE
4
To put one brick upon another Add a third and
then a fourth, Leaves no time to wonder
whether What you do has any worth. But to sit
with bricks around you While the winds of heaven
bawl Weighing what you should or can do Leaves no
doubt at it at all. Philip Larkin 1951