Simulation of a rod photoreceptor for use in a realistic retina model Rodrigo Publio, Rodrigo F' Oli - PowerPoint PPT Presentation

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Simulation of a rod photoreceptor for use in a realistic retina model Rodrigo Publio, Rodrigo F' Oli

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Simulation of a rod photoreceptor for use in a realistic retina model ... The photocurrent is directly injected into the outer segment and passively ... – PowerPoint PPT presentation

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Title: Simulation of a rod photoreceptor for use in a realistic retina model Rodrigo Publio, Rodrigo F' Oli


1
Simulation of a rod photoreceptor for use in a
realistic retina modelRodrigo Publio, Rodrigo
F. Oliveira and Antonio C. Roque
  • First step of a retina model rod photoreceptor

Inner segment
Outer segment
Rod Model Photocurrent ( final step of
transduction )
2
  • Compartmental model in NEURON

Figure 1 - Simulated rod photoreceptor. The
photocurrent is directly injected into the outer
segment and passively propagates to inner segment.
3
  • Responses of rod model

B
A
D
C
Ih current effect
Figure 2 - Simulated light responses. (A)
Photocurrent Amplitude steps (B) Calcium
current. (C) Hyperpolarization current. (D)
Voltage responses.
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