Birth Certificate data is crucial for medical research

1
Birth Certificate data is crucial for medical
research
2
Reproductive Health Report Card
3
The Problem

• Rates of congenital anomalies and prematurity
  havent changed in 30 years
• Science has failed the pregnant woman!

4
The Birth Certificate as an information hub
5
The Birth Certificate as an information hub
6
The Birth Certificate as an information hub

• Birth Certificate
• low birth weight
• prematurity

• Infant Death Certificate
• All causes of childrens diseases

7
The Birth Certificate as an information hub

• Birth Certificate
• low birth weight
• prematurity

• Birth Defects Registry
• Structural congenital anomalies

• Infant Death Certificate
• All causes of childrens diseases

8
The Birth Certificate as an information hub

• Birth Certificate
• low birth weight
• prematurity

• Birth Defects Registry
• Structural congenital anomalies

• Infant Death Certificate
• All causes of childrens diseases

• National Death Index
• Deaths among pregnant women

9
The Birth Certificate as an information hub

• Pregnancy Blood Samples
• Exposures in mom

• Birth Certificate
• low birth weight
• prematurity

• Birth Defects Registry
• Structural congenital anomalies

• Infant Death Certificate
• All causes of childrens diseases

• National Death Index
• Deaths among pregnant women

10
Discovering Causes Through Bio-Research

• California Birth Defects Monitoring Program banks
  blood samples on 100,000 pregnant women per year.
• As of June 2006, we have banked 290,000 pregnant
  womens blood samples.

11
Discovering Causes Through Bio-Research

• Each sample is split into two serum specimens
  stored at -70C and one clot stored at -20C.
• Samples are banked at Long Beach Memorial Medical
  Center, Long Beach, California.

12
Discovering Causes Through Bio-Research

• Pregnancy blood samples are collected between
  15-19 weeks
• Urban, rural, multi-racial and socioeconomically
  diverse population

13
Discovering Causes Through Bio-Research

• Childhood diseases that can be studied with blood
  samples

• Birth defects
• Mental retardation
• Low birth weight

Prematurity Childhood cancer Autism
14
Discovering Causes Through Bio-Research

• Risk factors that can be studied with blood
  samples

• Medications
• Infections
• Chemicals

• Diet
• Lifestyle
• Genetic

15

• Pregnancy Blood Samples
• Exposures in mom

• Birth Certificate
• low birth weight
• prematurity

• Birth Defects Registry
• Structural congenital anomalies

• Infant Death Certificate
• All causes of childrens diseases

• National Death Index
• Deaths among pregnant women

16
Summary

• We need to find causes of childrens diseases

17
Summary

• We need to find prenatal antecedents of adult
  diseases

18
Summary

• To do this we need to link birth certificate data
  with pregnancy blood samples and health outcomes
  among children and adults