REYES SYNDROME

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REYES SYNDROME

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• By Alea Schlimpert

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What is Reyes Syndrome

• Reyes Syndrome is a rare, yet serious childhood
  disorder that causes inflammation of the brain
  and quick build-up of fat in the liver. (1) It
  usually occurs after a viral illness such as
  influenza or chicken pox. (2)

3
History

• Discovered in 1963 by Dr. Ralph Reye. (3)

4
Cause

• Exact cause is uncertain.
• Research indicates it is caused by a negative
  bodily reaction to aspirin given during a viral
  illness. (2)

5
Symptoms

• Vomiting
• Mental Confusion
• Lethargy
• Seizures
• Difficulty breathing
• Fever
• Rash (seldom)

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Diagnosis

• Blood test
• Lumbar procedure (spinal tap)
• Biopsy of the liver

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Prevalence

• Rare! (2)
• Majority inflicted are infants, children, or
  adolescents
• Occurs equally in males and females (4)
• New statistics claim that it occurs in fewer than
  20 children in the United States each year. (1)

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Treatment

• Depends on
• Symptoms
• Severity of mental changes
• rate at which the disorder is progressing
• Medication (5)
• Antibiotics
• Liquids
• Vitamin K

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Prognosis

• Depends on how bad the damages are to the central
  nervous system.
• Mortality rate used to be 90 today it is about
  20 (thanks to monitoring and early treatment)
• Once in a coma state, death is bound to occur.
• Children who survive the acute phase recover
  fully. (1)

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Sources

• Berkow, Robert M.D., The Merck Manual of Medical
  Information. Merck Research Laboratories, 1997.
• Komaroff, Anthony L. Harvard Medical School
  Family Health Guide. New York Simon Schuster,
  1999.
• The Reye Syndrome Story. 16 Oct.
  2002lthttp//members.aol.com/leibert/reyessynd.htmgt
  .
• Cahill, Matthew. Professional Guide to Diseases.
  6th ed. Springhouse Springerhouse Corporation,
  1998.
• Magalini, Sergio I., Magalini, Sabina C., and de
  Francisci, Giovanni. Dictionary of Medical
  Syndromes. 3rd ed. Philadelphia J.P. Lippincott
  Company of Philadelphia, 1990.