Protein Metabolism

1
Protein Metabolism
2
Protein Metabolism
3
Nitrogen Pool
4
Transamination
5
Transamination
6
Transamination
7
Oxidative Deamination
8
Oxidative Deamination
9
Oxidative Deamination
10
Urea Cycle
11
PKU - Phenylketonurea
12
Other errors of metabolism

• B. Goitrous Cretinism D. Tyrosinosis
• C. Albinism E. Alkaptonuria

13
Heme Catabolism

• Heme to Bilirubin in liver to gall bladder to
  small intestine
• Converted to urobilinogen reabsorbed to blood,
  liver, kidney

14
Bilirubin

• Heme to bilirubin to bilirubin diglucuronide
  (soluble)

15
Jaundice Lab Test

• LAB TEST
•   Normal Biliary Hepatic Hemolytic
  Obstruction Diseases Diseases
•  Bilirubin Neg. Pos. Pos. Neg.
• Urobilinogen Pos. Neg. Pos. or low Pos. high

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Summary of Metabolism
17
Diagnostic Serum Enzymes
18
Alcohol Metabolism Effects