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Title: Dr. Hayden’s Advanced Nerve & Natural Nervous System Support Supplement (1)


1
Garlic for Hypertension Introduction Garlic,
also known as Allium sativum, is an edible bulb
from a plant in the lily family that is native to
Siberia.1,2 Garlic is used widely as a flavoring
in cooking. Throughout the history, garlic has
been used to treat bronchitis, hypertension,
tuberculosis, liver disorders, intestinal worms,
diabetes, and fevers.3 Currently, garlic is used
as a dietary supplement for hypertension, high
cholesterol, and common cold.1 What is
hypertension? Hypertension is a condition where
the blood pressure is consistently too high.4
Blood pressure is recorded as two numbers
systolic blood pressure (first number) and
diastolic blood pressure (second number).
Systolic blood pressure represents the pressure
of the blood against the artery walls as the
heart beats.5 On the other hand, diastolic
pressure is the pressure of the blood against the
artery walls while the heart is resting between
beats.5 Blood pressures of less than 120/80 mmHg
are considered normal. When the blood pressure
goes above 130/80 mmHg, that is considered
hypertension. Hypertension increases the
workload of the heart and blood vessels.4 Over
time, this damages the tissues inside the
arteries.4 If left untreated or uncontrolled,
hypertension can lead to heart attack, stroke, or
even death. Hypertension usually has no
symptoms, so getting the blood pressure measured
is the only way to know if you have it. Many
prescription medications are available for the
treatment of hypertension. How does garlic lower
blood pressure? It is not completely understood
how garlic works in the body. Garlic produces a
chemical called allicin. Allicin is thought to
be responsible for lowering blood pressure.2
Garlic may increase a chemical in the body
called nitric oxide, which relaxes and dilates
the blood vessels. This allows blood to flow more
freely, thus lowering the blood pressure.6 There
have been numerous studies done on garlic and how
it affects the blood pressure. A 2010 randomized
controlled trial assessed the effect of aged
garlic extract as an additional therapy in
patients who have uncontrolled hypertension
despite taking hypertension prescription
medications.7 The participants were given either
aged garlic extract 960 mg daily for 12 weeks or
placebo daily for 12 weeks. The average systolic
blood pressure decreased by 10.2 mmHg in the
garlic group, in comparison to the placebo
group. A 2016 study investigated the effect of
aged garlic extract on blood pressure and other
cardiovascular risk factors in patients with
uncontrolled hypertension.8 The study
participants were randomly assigned to aged
garlic extract 1.2 g daily for 12 weeks or
placebo daily for 12 weeks. In the garlic group,
the average systolic blood pressure was
significantly reduced by 11.5 mmHg. And, the
average diastolic blood pressure was reduced by
6.3 mmHg. A meta-analysis done in 2016 reviewed
20 clinical trials on the effect of garlic
supplements on blood pressure.9 Overall, the
average systolic blood pressure decreased by 5.1
mmHg and the average diastolic blood pressure
decreased by 2.5 mmHg. In participants with blood
pressures 140/90 mmHg at the start of the
clinical trials, greater reductions in systolic
blood pressure (by 8.7 mmHg) and diastolic blood
pressure (by 6.1 mmHg) were observed.
2
Lastly, a recent review and meta-analysis
published in 2020 looked at 12 clinical trials on
the effect of garlic on blood pressure in people
with hypertension.10 Garlic reduced the systolic
blood pressure by an average of 8.3 mmHg and the
diastolic blood pressure by an average of 5.5
mmHg, which were very similar to the reductions
by the standard hypertension prescription
medications. This reduction in blood pressure
was associated with a 16-40 reduction in the
risk of developing heart disease. How do you
take garlic? The garlic supplement is made from
the bulb of the garlic plant.1 The supplement is
available as tablets, capsules, and topical
oil.1 Garlic is not approved as a drug by the
Food and Drug Administration (FDA). It can be
challenging to determine how much garlic to
consume as there are no official recommended
dosages. It is recommended to start with a low
dosage and increase slowly until the desired
effect is reached. Prior to using garlic, have a
discussion with your doctor to make sure it is
appropriate to use. Safety of garlic Garlic is
generally well tolerated. Most common side
effects are bad breath, body odor, heartburn, and
upset stomach.1,2 Garlic may cause an increase
in the bleeding risk. There have been reports of
bleeding after surgery in people taking garlic.2
The safety of garlic during pregnancy and
lactation has not been well studied.2 Garlic
does not have serious interactions with any
medications. It may reduce the level of isoniazid
(a tuberculosis medication) in the body, leading
to the decreased effectiveness of isoniazid.2
Garlic may also increase the rate of breakdown
of some HIV/AIDS drugs, so they are not as
effective in treating HIV/AIDS.2 In addition,
garlic interacts with oral contraceptives and
anticoagulants/antiplatelets.2 It may reduce the
level of estrogens in the body, reducing the
effectiveness of oral contraceptives.2 It slows
blood clotting. So, taking garlic with
anticoagulants (e.g. warfarin, heparin, Lovenox,
Eliquis, Xarelto) or antiplatelets (e.g.
aspirin, Plavix) may increase the risk of
bleeding.2 Conclusion Garlic is currently used
as a dietary supplement for hypertension. It
works in the body by increasing a chemical in
the body called nitric oxide. This causes
relaxation and dilation of blood vessels, leading
to the lowering in blood pressure. Study
findings showed that garlic lowered blood
pressure in people with hypertension. Before
using garlic for hypertension, please consult
your doctor to determine that it is safe and
appropriate for you. You can find various
supplement and health related tips and articles
from our website natures-
reveal.com
  • References
  • Garlic. National Center for Complementary and
    Integrative Health. https//www.nccih.nih.gov/hea
    lth/garlic. Sept. 2016. Accessed Oct. 22, 2020.
  • Garlic. WebMD. https//www.webmd.com/vitamins/ai
    /ingredientmono-300/garlic. Accessed Oct. 22,
    2020.
  • What are the benefits of garlic? Medical News
    Today. https//www.medicalnewstoday.com/articles/
    265853. Aug. 18, 2017. Accessed Oct. 23, 2020.
  • What is High Blood Pressure? American Heart
    Association. https//www.heart.org/en/health-
    topics/high-blood-pressure/the-facts-about-high-bl
    ood-pressure/what-is-high-blood-pressure. Oct.
    13, 2016. Accessed Oct. 23, 2020.

3
  • Understanding Blood Pressure Readings. American
    Heart Association. https//www.heart.org/en/healt
    h-topics/high-blood-pressure/understanding-blood-p
    ressure- readings. Oct. 23, 2020.
  • Ried, Karin, and Peter Fakler. Potential of
    garlic (Allium sativum) in lowering high blood
    pressure mechanisms of action and clinical
    relevance. Integrated blood pressure control
    vol. 7 71-82. 9 Dec. 2014, doi10.2147/IBPC.S5143
    4
  • Ried, Karin et al. Aged garlic extract lowers
    blood pressure in patients with treated but
  • uncontrolled hypertension a randomised
    controlled trial. Maturitas vol. 67,2 (2010)
    144-50. doi10.1016/j.maturitas.2010.06.001
  • Ried, Karin et al. The effect of aged garlic
    extract on blood pressure and other
    cardiovascular risk factors in uncontrolled
    hypertensives the AGE at Heart trial.
    Integrated blood pressure control vol. 9 9-21.
    27 Jan. 2016, doi10.2147/IBPC.S93335
  • Ried, Karin. Garlic Lowers Blood Pressure in
    Hypertensive Individuals, Regulates Serum
  • Cholesterol, and Stimulates Immunity An Updated
    Meta-analysis and Review. The Journal of
    nutrition vol. 146,2 (2016) 389S-396S.
    doi10.3945/jn.114.202192
  • Ried, Karin. Garlic lowers blood pressure in
    hypertensive subjects, improves arterial
    stiffness and gut microbiota A review and
    meta-analysis. Experimental and therapeutic
    medicine vol. 19,2 (2020) 1472-1478.
    doi10.3892/etm.2019.8374
  • Visit our website for more information about
    health and Supplement
  • natures-reveal.com
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