Renal Tubular Acidosis: Causes, Symptoms, Daignosis, Prevention and Treatment - PowerPoint PPT Presentation

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Renal Tubular Acidosis: Causes, Symptoms, Daignosis, Prevention and Treatment

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Renal Tubular Acidosis can be referred to as the electrolytic disturbance that is caused because of impaired excretion of renal hydrogen ions, impaired bicarbonate resorption or abnormal production of aldosterone. – PowerPoint PPT presentation

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Title: Renal Tubular Acidosis: Causes, Symptoms, Daignosis, Prevention and Treatment


1
Renal Tubular Acidosis
2
Renal Tubular Acidosis
  • Renal tubular acidosis can be referred to as the
    electrolytic disturbance that is caused because
    of impaired excretion of renal hydrogen ions,
    impaired bicarbonate resorption or abnormal
    production of aldosterone.This condition leads
    to a chronic metabolic acidosis with a gap in an
    anion. Usually, hyperchloremia or excess of
    chlorine in blood may be present. Some of the
    other features may be with electrolytes of
    potassium and calcium.Chronic renal tubular
    acidosis is associated with damages of renal
    tubules in your kidneys. If ignored or not
    diagnosed at the right time, this condition may
    lead to chronic kidney diseases. 

3
Renal Tubular Acidosis
Continue
  • Renal tubular acidosis is classified based on
    the mechanism involved. If the impairment is with
    hydrogen ion excretion, the disorder is called
    Type 1 renal tubular acidosis.In Type 2 renal
    tubular acidosis, impairment is caused due to
    bicarbonate resorption. In Type 4 renal tubular
    acidosis, the defect is caused by decrease in the
    level of aldosterone. Type 4 is quite common,
    whereas type 1 is rare and type 2 is extremely
    rare.

4
Causes of Renal Tubular Acidosis
  • The causes of type 1 renal tubular acidosis
    could be
  • Sjögren's syndrome
  • Hyperparathyroidism
  • Lupus
  • Analgesic nephropathy
  • Kidney transplant rejection
  • A hereditary form of deafness
  • Renal medullary cystic disease
  • Obstructive uropathy
  • Chronic urinary tract infections

5
Causes of Renal Tubular Acidosis
Continue
  • The causes of type 2 renal tubular acidosis
    could be 
  • Kidney transplant rejection
  • Wilsons disease
  • Fanconi syndrome
  • Cystinosis
  • Hereditary fructose intolerance
  • Multiple myeloma

6
Causes of Renal Tubular Acidosis
Continue
  • The causes of type 4 renal tubular acidosis
    could be
  • Obstructive uropathy
  • Addisons disease
  • Syndrome Hyporeninemic Hypoaldosteronism
  • Heparin
  • Potassium sparing Diuretics
  • Diabetic Nephropathy
  • Interstitial Nephritis

7
Prevention
  • Unfortunately, most of the causes of renal
    tubular acidosis are not preventable. However,
    following are some prevention measures you can
    adopt
  • Maintain your health by consuming healthy food
  • Balance the levels of blood pressure and diabetes
  • Regularly exercise

8
How is Renal Tubular Acidosis diagnosed?
  • Renal tubular acidosis can be easily diagnosed
    using the following methods
  • Urine Tests
  • Acid Load Test
  • Physical Examination

9
Symptoms of Renal Tubular Acidosis
  • Usually, renal tubular acidosis is asymptomatic
    in nature, meaning that it causes no symptoms or
    signs. It is rare for a severe electrolyte
    imbalance to happen, but in case it does, your
    situation could be life-threatening. Some
    symptoms of renal tubular acidosis are
  • Nephrolithiasis or Kidney stones
  • Nephrocalcinosis (Calcium deposits in kidney)
  • Electrolyte excretion
  • Extracellular fluid volume depletion
  • Muscle weakness

10
Symptoms of Renal Tubular Acidosis
Continue
  • Hyporeflexia
  • Paralysis
  • Bone pain in adults
  • Rickets in children
  • Cardiac arrhythmia

11
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