Nonalcoholic fatty liver: Causes, Symptoms, Daignosis, Prevention and Treatment - PowerPoint PPT Presentation

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Nonalcoholic fatty liver: Causes, Symptoms, Daignosis, Prevention and Treatment

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Nonalcoholic fatty liver disease is a condition in which the liver stores excess fat but is not secondary to alcohol, a virus, drugs, metabolic disorders, syndromes and other factors that may affect the liver’s ability to metabolize or export fat. – PowerPoint PPT presentation

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Title: Nonalcoholic fatty liver: Causes, Symptoms, Daignosis, Prevention and Treatment


1
Nonalcoholic fatty liver disease
2
Nonalcoholic fatty liver disease (NAFLD)
  • Nonalcoholic fatty liver disease (NAFLD) is a
    condition in which the liver stores excess fat
    but is not secondary to alcohol, a virus, drugs,
    metabolic disorders, syndromes and other factors
    that may affect the livers ability to metabolize
    or export fat. The disease process is usually
    associated with obesity, abnormal lipid levels
    (high cholesterol), diabetes, and
    prediabetes. Severity of Nonalcoholic fatty
    liver disease (NAFLD) can range from fat storage
    in the liver, fat and inflammation in the liver,
    fat and inflammation with a lot of scar tissue in
    the liver (cirrhosis due to NASH).

3
Causes of Nonalcoholic fatty liver disease
(NAFLD)
  • Nonalcoholic fatty liver disease (NAFLD) can be
    understood as excess energy storage in the form
    of fat within the liver. When the balance between
    energy going out is less than energy coming in
    (food), the liver may store excess energy in the
    form of fat.

4
Diagnosis of Nonalcoholic fatty liver disease
  • The diagnosis of Nonalcoholic fatty liver
    disease (NAFLD) requires the presence of fat in
    the liver as seen by imaging studies or histology
    and the exclusion of other causes of fat
    accumulation. Many things can disturb the
    livers metabolic activity and it is vital to
    remove those things as the treatment relies on
    the underlying cause of the problem. Currently
    the only way to distinguish between non-NASH
    NAFLD and NASH is a liver biopsy, however several
    risk calculators and biomarkers have been devised
    to help determine whether a biopsy is needed.

5
Signs Symptoms of Nonalcoholic fatty liver
disease
  • Nonalcoholic fatty liver disease (NAFLD) without
    cirrhosis is regarded as a clinically silent
    disease (does not have symptoms). Some patients
    report some general abdominal symptoms that may
    or may not be related to liver changes.

6
Treatments of Nonalcoholic fatty liver disease
  • The mainstay of treatment for Nonalcoholic fatty
    liver disease (NAFLD) and Non-alcoholic
    Steatohepatitis (NASH) are lifestyle changes
    weight loss, exercise and following a healthy
    diet. These treatments not only target the liver,
    but reduce overall cardiovascular risk, since
    cardiovascular complications are strongly
    associated with Nonalcoholic fatty liver disease
    (NAFLD). In people who have biopsy evidence of
    Non-alcoholic Steatohepatitis (NASH), current
    recommendations include vitamin E. This is not a
    general recommendation that should be started
    without consulting a physician since risks can be
    associated with it. Many other treatments for
    Non-alcoholic Steatohepatitis (NASH) are being
    developed and may be available in the near
    future.

7
Treatments of Nonalcoholic fatty liver disease
Continue
  • Although bariatric surgery can improve
    Nonalcoholic fatty liver disease (NAFLD) and
    Non-alcoholic Steatohepatitis (NASH), it is not
    recommended for those diagnoses alone at this
    time. Patients undergoing bariatric surgery
    frequently do not know they have liver
    disease. If a person has other indications for
    bariatric surgery and evidence of liver disease,
    then bariatric surgery may be performed but
    should be done with the consultation of a liver
    specialist.

8
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