An Overview of Liver Transplant-MedMonks - PowerPoint PPT Presentation

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An Overview of Liver Transplant-MedMonks


Individuals diagnosed with irreversible acute or chronic liver disease serve as the best candidates for liver transplantation – PowerPoint PPT presentation

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Title: An Overview of Liver Transplant-MedMonks

What is a liver transplant, Signs and Symptoms
, Who is a Potential Donor and Recipient,
Benefits and Side-Effects and Risks  
An Overview of Liver Transplantation
Liver transplantation is a procedure in which the
diseased liver (of the recipient) is replaced
with a fresh one (of the donor).
  • Being time-consuming and demanding, liver
    transplantation procedure is only performed on
    patients with liver failure or end-stage liver

Reasons for Liver Transplantation
The need of the liver transplant arises in
patients with liver failure. A variety of liver
disorders can result in liver failure. Some of
the most common liver diseases are 1. Acute
hepatitis (an inflammation in the liver tissue)-
Viral hepatitis, hepatitis A, B, C, D,
autoimmune hepatitis. 2. Fatty liver disease
(large vacuoles of fat build-up in liver cells
leading to dysfunction)
Reasons for Liver Transplantation
  • 3. Cirrhosis -scarring of the liver caused due to
    long-term damage.
  • 4. Cancer (caused when hepatitis, cirrhosis etc.
    aggravates)-Hepatocellular carcinoma (HCC),
    hepatoblastoma, Cholangiocarcinoma.
  • 5. Drug-induced liver issues Intake of
    prescription, over-the-counter (OTC) drugs,
    various types of herbal supplements, vitamins,
    and dietary supplements such as acetaminophen,
    Tylenol, and others for a long period of time can
    stop the liver to function normally.

  • Immune (defense) System abnormalities Genetic
    (hereditary) Abnormalities Due to disorders such
    as autoimmune hepatitis, primary biliary
    cirrhosis, and more, the immune system of the
    body begins to attack parts of the body including
  • Over consumption of alcohol and other reasons
    such as metabolic problems.

Signs and Symptoms
  • Skin and eyes appear yellowish (jaundice)
  • Bleeding and bruising
  • Swelling in the legs and ankles
  • Extreme Tiredness
  • abdominal pain,
  • Itchy skin,
  • Dark urine color,
  • Pale stool color, or bloody or tar-colored stool,
  • Nausea or vomiting,
  • and loss of appetite.

Who can be the recipient?
  • Individuals diagnosed with irreversible acute
    or chronic liver disease serve as the best
    candidates for liver transplantation. This
    decision is made by the surgeon and associated
    doctor purely on the basis of screening
    examinations and respective diagnostic

Who Cannot be a Recipient
  • There are a few conditions that
    disqualifies an individual from being added on
    the recipient list such absolute contradictions
    can be caused if the concerned patient is
    suffering from AIDS, metastatic cancer, chronic
    active infection, active substance abuse,
    advanced heart or lung disease, and chronic form
    of a liver disease coupled with serious alcohol

Who can be a Donor
  • To ensure the best results, two types of
    donor namely diseased donor and a living
    donor can be used in executing a liver
    transplantation process.
  • While the liver attained from a diseased
    donor (someone who has died) is used to perform
    the procedure on adult recipients, in particular,
    liver derived from the living donor is used to
    perform the surgery on younger patients.

Who cannot be a donor?
  • People suffering from a range of health
    conditions including, liver disease, diabetes,
    heart disease, or cancer fail to qualify.

Benefits of Liver Transplant
  • The life of the patient, who has undergone this
    surgery, increases. After the transplant, he or
    she can lead a normal, healthy and an active
    lifestyle in no time.
  • The recovery period is lower adhere to the
    strict guidelines, and routine checkups
    instructed by the surgeon or operating doctor.
    Also, one should take anti-rejection medications

Common Side-Effects of Liver Transplant
  • Due to intake of drugs that treat or prevent
    rejection, side-effects like fluid retention,
    raised blood pressure, headaches, diarrhea, and
    nausea can occur.

  • Factors such as heavy alcohol use, injection
    of drugs using shared needles, tattoos or body
    piercings, blood transfusion before 1992,
    exposure to other people's blood and body fluids,
    and harmful chemicals or toxins, unprotected sex,
    presence of health conditions like Diabetes,
    obesity can put enhance the risks of liver
    disease in the body.

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