Infections Caused by The Neisseria Meningitidis Bacteria - PowerPoint PPT Presentation

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Infections Caused by The Neisseria Meningitidis Bacteria

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Invasive meningococcal disease (IMD) is a life-threatening condition caused by the bacterium Neisseria meningitidis (N. meningitidis), an encapsulated gram-negative diplococcus that is a pathogen exclusive to humans. N. meningitidis is carried harmlessly in the nasopharynx of approximately 5?11% of adults and up to 25% of adolescents. Life-threatening disease occurs when the bacterium invades body tissue, which most commonly manifests as meningitis or septicemia. The disease is transmitted via respiratory droplets, through close or prolonged contact with an infected individual. N. meningitidis is classified into 13 distinct serogroups; however, almost all invasive disease in humans is a result of infection with one of 6 serogroups. – PowerPoint PPT presentation

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Title: Infections Caused by The Neisseria Meningitidis Bacteria


1
EpiCast Report Meningococcal Disease -
Epidemiology Forecast to 2025
Telephone 1 (800) 910-6452Mail at
sales_at_researchbeam.com
(Type, Mode of action, Crop Type and Geography) -
Size, Share, Global Trends, Company Profiles,
Demand, Insights, Analysis, Research, Report,
Opportunities, Segmentation and Forecast, 2013 -
2020
Published on Oct 2014
2


Report Overview
  • Summary
  • Invasive meningococcal disease (IMD) is a
    life-threatening condition caused by the
    bacterium Neisseria meningitidis (N.
    meningitidis), an encapsulated gram-negative
    diplococcus that is a pathogen exclusive to
    humans. N. meningitidis is carried harmlessly in
    the nasopharynx of approximately 5?11 of adults
    and up to 25 of adolescents. Life-threatening
    disease occurs when the bacterium invades body
    tissue, which most commonly manifests as
    meningitis or septicemia. The disease is
    transmitted via respiratory droplets, through
    close or prolonged contact with an infected
    individual. N. meningitidis is classified into 13
    distinct serogroups however, almost all invasive
    disease in humans is a result of infection with
    one of 6 serogroups.
  • In the 8MM, Epidemiologists forecast that the
    laboratory-confirmed incident cases of IMD will
    decrease from 4,153 cases in 2015 to 3,169 cases
    in 2025 at an Annual Growth Rate (AGR) of
    negative 2.37. Brazil had the highest number of
    laboratory-confirmed incident cases of IMD among
    the individual markets of the 8MM throughout the
    forecast period. The 5EU combined will account
    for 45.32 of laboratory-confirmed incident cases
    in 2015, and by 2025 this is forecast to increase
    to 59.58. In the 8MM in 2015, 43.37 of the
    laboratory-confirmed incident cases of IMD are
    serogroup C disease, 36.46 are serogroup B
    disease, 5.25 are serogroup Y disease, and
    14.98 are disease caused by other serogroups
    combined. Epidemiologists estimated that in the
    8MM in 2015, 10.86 of laboratory-confirmed
    incident cases of IMD would occur in the
    population less than 1 year of age.

3


Report Overview
  • Scope
  • - The Meningococcal disease (IMD) EpiCast Report
    provides an overview of the risk factors,
    comorbidities, and the global and historical
    trends for IMD in eight major markets (8MM) (US,
    France, Germany, Italy, Spain, UK, Japan, and
    Brazil). For the US, 5EU (France, Germany, Italy,
    Spain, and UK), and Brazil, it includes a 10-year
    epidemiological forecast for laboratory-confirmed
    incident cases of all IMD (all serogroups
    combined), segmented by sex and age (in age
    groups of lt1 year and 1-4 years, then in 10 year
    age groups to 65 years), and laboratory-confirmed
    incident cases of serogroup B, serogroup C,
    serogroup Y, and all other IMD combined. For
    Japan, it includes a 10-year epidemiological
    forecast for laboratory-confirmed incident cases
    of IMD segmented by sex and age (lt1 year and 1
    year) and a 10-year epidemiological forecast for
    laboratory-confirmed incident cases of specific
    serogroups. For the US, this report also provides
    a 10-year forecast of the number of first-year
    college students and the number of first-year
    college students living in campus accommodation.
  • - The IMD epidemiology report is written and
    developed by Masters- and PhD-level
    epidemiologists.
  • - The EpiCast Report is in-depth, high quality,
    transparent and market-driven, providing expert
    analysis of disease trends in the 8MM.
  • Reasons to buy
  • - Develop business strategies by understanding
    the trends shaping and driving the global IMD
    market.
  • - Quantify patient populations in the global IMD
    market to improve product design, pricing, and
    launch plans.
  • - Organize sales and marketing efforts by
    identifying the age groups and sex that present
    the best opportunities for IMD therapeutics in
    each of the markets covered.

4


Table of Contents
1 Table of Contents 4 1.1 List of Tables 6 1.2
List of Figures 7 2 Epidemiology 8 2.1 Disease
Background 8 2.2 Risk Factors and morbidities
9 2.3 Global Trends 12 2.4 Forecast Methodology
17 2.4.1 Sources Used Tables 18 2.4.2 Forecast
Assumptions and Methods 25 2.5 Epidemiological
Forecast for IMD (2015-2025) 40 2.5.1 All IMD
Combined 40 2.5.2 Laboratory-Confirmed Incident
Cases of Serogroup B IMD 50 2.5.3
Laboratory-Confirmed Incident Cases of Serogroup
C IMD 53 2.5.4 Laboratory-Confirmed Incident
Cases of Serogroup Y IMD 55 2.5.5
Laboratory-Confirmed Incident Cases of Other
Serogroup IMD 57 2.5.6 Distribution of Serogroups
59 2.6 Discussion 62 2.6.1 Epidemiological
Forecast Insight 62 2.6.2 Limitations of the
Analysis 64 2.6.3 Strengths of the Analysis 65 3
Appendix 66
5


List of Figures
Figure 1 Laboratory-Confirmed Incidence of IMD
in the EU, All Ages, Both Sexes, 2000-2014
14 Figure 2 8MM, Laboratory-Confirmed Incident
Cases of all IMD, All Ages, Both Sexes, N,
Selected Years 2015-2025 43 Figure 3 7MM,
Age-Specific Laboratory-Confirmed Incident Cases
of IMD, Both Sexes, 2015 46 Figure 4 8MM,
Laboratory-Confirmed Incident Cases of All IMD,
All Ages, Both Sexes, N, 2015 48 Figure 5 8MM,
Age-Standardized Laboratory-Confirmed Incidence
(Cases per 100,000 Population) of IMD, All Ages,
by Sex, 2015 50 Figure 6 8MM, Laboratory-Confirme
d Incident Cases of Serogroup B IMD, All Ages,
Both Sexes, N, Selected Years 2015-2025 53 Figure
7 8MM, Laboratory-Confirmed Incident Cases of
Serogroup C IMD, All Ages, Both Sexes, N,
Selected Years, 2015-2025 55 Figure 8 8MM,
Laboratory-Confirmed Incident Cases of Serogroup
Y IMD, All Ages, Both Sexes, N, Selected Years,
2015-2025 57 Figure 9 8MM, Laboratory-Confirmed
Incident Cases of Other Serogroup IMD, All Ages,
Both Sexes, N, Selected Years, 2015-2025
59 Figure 10 8MM, Serogroup Distribution of
Laboratory-Confirmed Incident IMD Cases, , 2015
60 Figure 11 8MM, Serogroup Distribution of
Laboratory-Confirmed Incident IMD Cases, , 2025
61 Figure 12 College Freshmen Living in Campus
Accommodation in the US, All Ages, Both Sexes, N,
Selected Years, 2015-2025 62
6


Report Ordering
Report Name EpiCast Report
Meningococcal Disease - Epidemiology
Forecast to 2025
Product Price
User Price
Single User US 3396
Site User US 7990
Global User US 11985
To View Sample or Purchase Report
7



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