Autism’s Rising Prevalence and Drug Discovery Efforts in 2016 A Review

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Autisms Rising Prevalence and Drug Discovery
Efforts in 2016 A Review
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• Autism is a neurodevelopmental disorder that is
  characterized by impaired social interaction,
  communication (both, verbal and non-verbal),
  restricted as well as repetitive behavior. These
  signs are usually noticed in the first two years
  of the childs life.

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• They often develop gradually, though some
  children with autism proceed to develop normally,
  and then regress. One of the criteria for
  diagnosis is that the symptoms should become
  apparent in early childhood, typically before age
  three.

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• Autism generally falls under a range of
  associated diseases, known as Autism Spectrum
  Disorders (ASD), that are characterized by
  similar symptoms.

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• Many medications are used to treat ASD symptoms
  that interfere with integrating a child into a
  standard environment when behavioral treatment
  fails.

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Countries with Highest Autism Prevalence (per 10,
000 people)
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Pharmacology (Causes)

• Autism is a complex disorder which is often
  caused by the co-occurrence of common cause at
  the genetic, cognitive, and neural levels.
  Although, it is clear that autism has strong
  genetic basis but the exact mechanism is still
  not known.

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• The major hypothesis relied on rare mutations
  with major effects or by rare multigene
  interactions of common genetic variants. 

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