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Title: Aarkstore - Stem Cell Research Products - Opportunities, Tools, and Technologies (1)


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Category Healthcare
Stem Cell Research Products - Opportunities,
Tools, and Technologies
  • Browse Complete Report -
  • http//www.aarkstore.com/healthcare/53012/stem-cel
    l-research-products-opportunities-tools-and-techno
    logies

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Executive Summary
Stem cells are primitive cells found in all
multi-cellular organisms that are characterized
by self-renewal and the capacity to differentiate
into any mature cell type. Stem cells are still
a relatively new discovery, as the first mouse
embryonic stem cells were derived from embryos in
1981, but it was not until 1995 that the first
successful culturing of embryonic stem cells from
non-human primates occurred and not until
November 1998 that a technique was developed to
isolate and grow embryonic stem cells from human
blastocysts. In 2006, induced pluripotent stem
cells were produced for the first time from mouse
cells and in 2007 they were produced from human
cells. Furthermore, it was not until 2008 that
the first full transplant of a human organ grown
from adult stem cells was performed when a
section of trachea was successfully transplanted
into an adult woman in Spain.
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Executive Summary
As of 2014, several broad categories of stem
cells exist, including Embryonic stem cells,
derived from blastocysts Fetal stem cells,
obtained from fetuses Post-natal stem cells,
derived from newborn tissues Adult stem cells,
found in adult tissues including Hematopoietic
stem cells, Mesenchymal stem cells, and Neural
stem cells Cord blood stem cells, isolated from
umbilical tissue Dental stem cells, derived from
deciduous teeth Induced pluripotent stem cells,
reprogrammed from adult cells Cancer stem cells,
which give rise to clonal populations of cells
that form tumors or disperse in the body Animal
stem cells, derived from non-human sources
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Executive Summary

The past 10 years have also witnessed the
production of novel stem cell types, including
piPSCs, R-NSCs, and VSELs. Together, this
evidence suggests that additional types of stem
cells will likely be discovered, each
representing new opportunities for research
product development. Clearly, laboratory research
into stem cell derivation, manipulation, and
application is rapidly expanding. To facilitate
research resulting from these advances, a large
and diverse stem cells products market has
emerged. Large companies selling stem cell
research products include Thermo Fisher
Scientific (now merged with Life Technologies),
BD Biosciences, EMD Millipore, Sigma Aldrich, and
STEMCELL Technologies, as well as over one
hundred other suppliers.
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Table of Content
  • ABSTRACT II. BACKGROUND TYPES OF STEM CELLS A.
    Human Embryonic Stem Cells (hESCs) 1. Early, 5-7
    days (totipotent) 2. Gonadal Ridge, 6 months
    (multipotent) B. Fetal Stem Cells
    (pluripotent) C. Umbilical Cord Stem Cells
    (multipotent) 1. Cord Blood  2. Cord Matrix
    (Whartons Jelly) D. Adult Stem Cells
    (multipotent) 1. Hematopoietic Stem Cells  2.
    Mesenchymal Stem Cells
  • 3. Neural Stem Cells 4. Dental Stem Cells
    (multipotent) E. Cancer Stem Cells
    (multipotent) F. Induced Pluripotent Stem Cells
    (iPSCs) G. Novel (recently discovered and
    uncharacterized) Stem Cell Types 1. Neural
    Rosette Cells (R-NSCs) 2. Very Small Embryonic
    Like (VSEL) Stem Cells
  • H. Stimulus-Triggered Acquisition of Pluipotency
    (STAP) Cells Unverified

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Table of Content
III. TIMELINE OF KEY STEM CELL EVENTS IV. STEM
CELL RESEARCH APPLICATIONS A. Regenerative
Medicine (Cell-Based Therapies) 1. Diabetes
Mellitus  2. Cardiovascular Disease 3.
Neurological Disease 4. Autoimmune Disease 5.
Hematopoietic Disease and Transplantation
Research  6. Orthopedic Repair 7. Cancer
Research 8. Birth Defect Research B. Drug
Development Discovery 1. Assays to Aid Early
Stage Discovery 2. Improved Prediction of Human
Responses 3. Drug Development with Humanized
Mouse Models 4. Genetically-Engineered Stem Cell
Lines for Screening 5. Pluripotent Stem Cell
Lines for Target Validation and Drug Screening 6.
Summary - Use of Stem Cells in Drug Development
Discovery
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Table of Content
V. KEY MARKET COMPETITORS PROVIDERS OF DIVERSE
STEM CELL PRODUCT LINES  A. Thermo Fisher
Scientific (Recently Merged with Life
Technologies / Includes Invitrogen Brand) 1. Stem
Cell Products a. Isolation and Characterization
Products b. Expansion and Differentiation
Products 2. Collaborations a. Invitrogen and
Cellartis AB b. Invitrogen and Novocell c.
Invitrogen and the Buck Institute d. Life
Technologies and Cellular Dynamics
International e. Life Technologies and iPS
Academia Japan f. Life Technologies and Harvard
University g. Life Technologies and DNAVEC
Corporation  B. BD Biosciences 1. Stem Cell
Products a. Isolation  b. Culturing c.
Analysis 2. Collaborations BD Biosciences and
STEMCELL Technologies
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Table of Content
VI. PRODUCT AREAS A. Primary Antibodies  B.
Bead-based Cell Separations Systems C.
Fluorescent-based Labeling and Detection D.
Protein Purification and Analysis Tools  1.
Protein Purification 2. Stem Cell Protein
Analysis 3. Quantitative Proteomics E. DNA/RNA
Based Characterization 1. Tools for DNA- and
RNA-based Characterization 2. Stem Cell HLA
Typing 3. Stem Cell Nucleic Acid Extraction and
Purification, PCR/qRT-PCR Reagents F. Isolation /
Characterization Services 1. Stem Cell HLA Typing
Services 2. Stem Cell Custom Services 3. Stem
Cell Custom Antibodies G. Stem Cell Culture Media
and Reagents H. Growth Factors and Cytokines
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Market Research Reports
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Stem Cell Research Products - Opportunities,
Tools, and Technologies Published Jun 2014
155 Pages Stem cells are primitive cells found
in all multi-cellular organisms that are
characterized by self-renewal and the capacity to
differentiate into any mature cell type. Price
Format Price
PDF 3495
Hard Copy 3545
Site License   4495
Enterprise Wide Licence 5495
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