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Aarkstore.com - Complete 2013-14 Induced Pluripotent Stem Cell (iPSC) Industry Report

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Stem cell research and experimentation has been in process for well over five decades, as stem cells have the unique ability to divide and replicate repeatedly. In addition, their “unspecialized” nature allows them to differentiate into a wide variety of specialized cell types. Browse Full Report @ – PowerPoint PPT presentation

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Title: Aarkstore.com - Complete 2013-14 Induced Pluripotent Stem Cell (iPSC) Industry Report


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Category Healthcare
Complete 2013-14 Induced Pluripotent Stem Cell
(iPSC) Industry Report
  • Browse Complete Report -
  • http//www.aarkstore.com/healthcare/51108/Complete
    -2013-14-Induced-Pluripotent-Stem-Cell-iPSC-Indust
    ry-Report

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Summary
Stem cell research and experimentation has been
in process for well over five decades, as stem
cells have the unique ability to divide and
replicate repeatedly. In addition, their
unspecialized nature allows them to
differentiate into a wide variety of specialized
cell types. The possibilities arising from these
characteristics have caused great commercial
interest, with potential applications ranging
from the use of stem cells in reversal or
treatment of disease, to targeted cell therapy,
tissue regeneration, pharmacological testing on
cell-specific tissues, and more. Diseases such as
Huntingtons Chorea, Parkinsons Disease, and
spinal cord injuries are examples of clinical
applications in which stem cells could offer
benefits in halting or even reversing
damage.Traditionally, scientists have worked
with both embryonic and adult stem cells as
research tools. While the appeal of embryonic
cells has been their ability to differentiate
into any type of cell, there has been significant
ethical, moral and spiritual controversy
surrounding their use for research purposes.
Although some adult stem cells do have
differentiation capacity, it is often limited in
nature, which creates narrow options for use.
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Discovery
Groundbreaking experimentation in 2006 led to the
introduction of induced pluripotent stem cells
(iPSC). These are adult cells which are isolated
and then transformed into embryonic-like stem
cells through the manipulation of gene
expression, as well as other methods. Research
and experimentation using mouse cells at Kyoto
University in Japan was the first instance in
which there was successful generation of the
iPSC. In 2007, a series of follow-up experiments
were done at Kyoto University in which human
adult cells were transformed into iPSC
cells. While there has been continued excitement
at the prospect of what such artificially
re-manufactured cells could contribute to medical
advances, there have also been issues along the
way. By 2010, there were a number of private
companies that were ready to capitalize on the
breakthrough technology that iPSCs represent. One
such company, Advanced Cell Technology in
Worcester, Massachusetts, discovered several
problematic issues while conducting experiments
for the purpose of applying for U.S. Food and
Drug Administration approval to use iPSCs in
therapeutic applications. Concerns such as
premature cell death, mutation into cancer cells,
and low proliferation rates were some of the
problems that surfaced.
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Table Of Content
I. ABSTRACTII. BACKGROUNDA. DefinitionB.
DiscoveryC. Advantages DisadvantagesIII.
TIMELINEA. Production of iPSCs (Key Events)B.
Full Timeline of Eventsnts
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Table Of Content
IV. RESEARCH APPLICATIONSA. Pharmaco-Toxicologic
al ScreeningB. Disease ModelingC. Autologous
Cell TransplantationD. Breakdown of iPSC
Research, By Applied Research ApplicationV.
CHARACTERIZATION OF iPSC RESEARCH ADVANCESA.
Methods of Making iPSCs Comparison of Methods
by Downstream ApplicationB. Summary of iPSC
Derivation Methods, by Cell TypeC. Diseases in
Which iSPCs Have Been Derived from Patients
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Complete 2013-14 Induced Pluripotent Stem Cell
(iPSC) Industry Report Published Feb 2014 127
Pages Stem cell research and experimentation
has been in process for well over five decades,
as stem cells have the unique ability to divide
and replicate repeatedly. Price
Format Price
PDF 3495
Hard Copy 3545
Site Licence 4495
Global Licence 5495
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Contact Us
  • You Can Visit http//www.aarkstore.com
  • OR Mail us at contact_at_aarkstore.com
  • Blog
  • http//www.aarkstore.com/blog/
  • Conference
  • http//conference.aarkstore.com/
  • News
  • http//www.aarkstore.com/news.php

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floor, B-wing, Hermes Atrium, Plot No.
57, Sector-11 CBD Belapur, Navi Mumbai -
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