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Human Genome Project

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1. Human Genome Project. Long completed; began 60 years ago. Goal is to understand & control ... The haplotypes in the human genome have been produced by the ... – PowerPoint PPT presentation

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Title: Human Genome Project


1
Human Genome Project
  • Long completed began 60 years ago
  • Goal is to understand control
  • Supercomputers are key
  • Bioinforamtics
  • Information science
  • Biology
  • Medicine
  • Genome mapping
  • Drug DNA matching
  • Predictive-preventive

2
Genotyping
  • Still controversial your DNA tells all
  • Genotyped people get best care
  • Single nucleotide polymorphisms (SNP)
  • 0.1 of total DNA
  • Only 20 main SNP classes
  • determines you and health characteristics.
  • SNP uses
  • Easier diagnosis predicable problems
  • Better preventative medicine
  • Customized medicine by SNP class

3
Genotyping cont.
The haplotypes in the human genome have been
produced by the mechanisms of reproduction and
record the history of our species.
They are closely linked genetic markers in a
chromosome inherited as a group
4
Bioinforamtics
  • DNA decoded Blue Gene unlocked code
  • 2005 180 days to decode the 3.2 billion DNA
    letters
  • 2055 decode/profile in 8 minutes and affordable
  • Today, diagnose, predict, fix/modify as required

BioMEMS analyzer
5
Important Bio-med Areas
  • Monitors - Implanted data via wireless.
  • Pharmacy-on-Chip provides medication
  • Gene modification
  • Nano-robotics for body maintenance and repair

6
Simple Bio Implants
wireless
Wireless Personal monitoring
7
Cosmetic Surgery
  • Popular
  • Standard library
  • Computerized
  • Mostly robotic (CAD-like)

8
Early Bio Detector
500 µm long, 100 µm wide and about 1 µm thick
IBM
Pathogen/Bad Gene Detector
9
Lab-on-Chip
DNA can be amplified, separated and identified on
a chip
10
Lab on Chip Diagram
11
Portable DNA Examples

Caliper Tech.
NanoChip Electronic Microarray
pumping occurs by applying electric voltage to
fluid.
Sandia
12
Sight Restoration 2015
Or link directly to
iHUD
13
FluidFocus Lens
Phillips
14
Sight Restoration 2055
  • Retina regeneration
  • Optic nerve repair
  • Replacement optics
  • Grown and transplanted bio-parts
  • Moving toward eye grown in place

15
Fantastic Journey?
  • Turbines
  • Tweezers
  • Cutters
  • Detectors
  • Sensors
  • Pumps
  • Legs
  • Wireless
  • Jets
  • More

16
Death
  • Intervention up to age 80
  • Euthanasia acceptable, but not suicide
  • You may be reactivated in suicide for obligations
  • Immortality research was banned in 2025
  • Near-mortality is feasible neg. consequences

17
Birth in the Brave New World
  • Parents/Donors DNA QCd
  • Gene adjustment OK
  • No super babies allowed
  • Minor modification gene defect repair
  • Gene libraries limited use
  • Will birth parents matter?
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