J-147 Powder (Step By Step) Complete Buying Guide and Review

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J-147 Powder (Step By Step) Complete Buying Guide and Review

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J147 Powder is an potent neuroprotective and neurotrophic compound, which have an Anti-Alzheimer disease and aging effects in an accelerated aging mouse model. 147 has been shown to enhance memory in normal animals and prevent memory deficits in mouse models of Alzheimer's disease and can improves spatial memory. For details visit us: – PowerPoint PPT presentation

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Title: J-147 Powder (Step By Step) Complete Buying Guide and Review


1
Buy S4(Andarine) Powder Online Everything You
Want To Know
www.aasraw.com aas18_at_aasraw.com Whatsapp86189293
48695 ?? 1. What is J-147 powder?..............
..................................................
..................................................
..................................................
........................................1 2.
SARMS J-147 powder Usage........................
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.................. 3 3. SARMS J 147 Dosage to Be
Taken.............................................
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..................................................
..................................... 4 4. The
Key Benefits Of Sarms J-147 Powder................
..................................................
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.... 6 5. What's the highlights of the report on
J-147 Powder testing?.............................
..................................................
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......... 7 6. Are There Any Side Effects When
Using J-147 Powder?...............................
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...............7 7. What product can take place
of Sarms J-147 powder?............................
..................................................
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.....................8 9. More SARMS Powder For
Choosing..........................................
..................................................
..................................................
.................................... 11 10. Where
To Get J-147 Powder source?.....................
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... 12
1. What is J-147 powder? J-147 Powder cas
1146963-51-0 is a potent neuroprotective phenyl
hydrazide compound(EC5060-115 nM) that protects
against neurotoxicity in cortical neurons in
vitro, it has significant neurotrophic properties
related to the induction of brain-derived
neurotrophic factor (BDNF). it was discovered
based upon efficacy in multiple cell culture
models of age-associated pathologies rather than
exclusively amyloid metabolism. It is an
exceptionally potent, orally active and broadly
neuroprotective compound has the ability to
enhance memory in normal animals as well as to
prevent memory deficits in Alzheimers disease
(AD) transgenic mice. These effects are
associated with an increase in brain derived
neurotrophic factor levels, enhanced long-term
potentiation, preservation of synaptic proteins,
a reduction of markers for oxidative stress and
inflammation, a reduction of amyloid plaques,
and lower levels of soluble amyloid ß.These
pleiotrophic effects of a single molecule suggest
that J-147 powder has potential for the treatment
of AD
2
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Name J-147 Powder
Synonyms J 147,J147
CAS 1146963-51-0
Molecular Weight 350.33
Molecular Formula C18H17F3N2O2
Storage Temp 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Purity 99(HPLC)
Chemical Name 2,2,2-Trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2- (3-methoxyphenyl)methylenehydrazide
Melt Point 177-178C
Color White or off white powder
Enhanced neurogenic activity over J-147 powder
cas 1146963-51-0 in human neural precursor cells
has its derivative called CAD-31. CAD-31 is
enhancing the use of free fatty acids for energy
production by shifting of the metabolic profile
of fatty acids toward the production of ketone
bodies, a potent source of energy in the brain
when glucose levels are low.The target molecule
is a protein called ATP synthase, which is found
in the mitochondria.
3
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2. SARMS J-147 powder Usage J147 Powder cas
1146963-51-0 was originally developed in 2011,
and AASraw researchers conducted some studies
demonstrating that it can reverse memory decline
and slow or reverse Alzheimer's disease in mice.
AASraw researchers use a variety of methods to
understand how J147 powder works. They finally
determined that the target of J147 powder is a
mitochondrial protein called ATP synthase,
especially ATP5A, a subunit of this protein. ATP
synthase is involved in the mitochondrial
production of ATP by cells for energy. By
reducing the activity of ATP synthase, they are
able to protect neuronal cells from multiple
types of toxicity associated with brain aging.
One reason for this neuroprotective effect is
thought to be the role of excitotoxicity in
neuronal cell injury. J147 Powder binds to
proteins found in mitochondria, the drug plays a
significant role. This is a powerful force for
cells, which in turn causes cells to function in
a younger way.
4
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48695 In a new study, the AASraw team discovered
that J147 powder cas 1146963-51-0 binds to a
protein called ATP synthase, which is responsible
for producing a common cellular "energy
currency", ATP. This protein is known to control
the aging of worms and flies. The researchers
found that by combining with drugs, the drug can
prevent age-related brain damage. The role of ATP
synthase in inhibiting neuroprotection against
excitotoxicity was demonstrated. The second
study showed that a mouse model that expresses
the human form of mutant ATPase inhibitor 1
(hIF1) (resulting in sustained inhibition of ATP
synthase) is more amenable to neuronal death
following excitotoxic injury. This data is
consistent with this new J147 study in which
increased IF1 in mice reduced the activity of ATP
synthase (especially ATP5A) and was
neuroprotective. The data presented here
indicate that J147 powder cas 1146963-51-0 has
the ability to rescue cognitive deficits upon
late administration of the disease. The ability
of J147 powder to improve memory function in aged
AD mice is related to its induction of the
neurotrophic factors NGF (nerve growth factor)
and BDNF (brain-derived neurotrophic factor) and
several BDNF-responsive proteins important for
learning and memory. A comparison of J147 powder
and scopolamine in scopolamine model shows that
although both compounds are comparable in saving
short-term memory, J147 powder is superior in
rescuing spatial memory, and the combination of
the two is most effective in contextual memory
and memory. In addition, AASraw studied other
molecules affected by J147 powder cas
1146963-51-0 in addition to ATP to find new drug
targets. At the same time, this drug has passed
the animal toxicology test and will enter the
first phase of the human clinical trial soon,
waiting for further funding
  • SARMS J 147 Dosage to Be Taken
  • The Recommend J147 Powder Dosage 20-30mg for
    neurological protection, neuroregenerative,
    anti-neurodegenerative, antidepressant, Alzheimer
    disease. 5-15mg for cognitive enhancement.
    Applications within sublingual hydroalcoholic-glyc
    erin based tinctures may be significantly
    superior.
  • In vitro sarms J 147 powder was used at 1 µM in
    vitro and in cellular assays.
  • In vivo sarms J 147 powder was orally dosed to
    mice at 1-5 mg/kg once per day. Or the transgenic
    mice were fed with sarms J 147 powder cas
    1146963-51-0 in their chow at 200 ppm starting at
    4 months of age.

5
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  • sarms J 147 powder estimated potential human
    clinical trial dosings J 147 dosing estimates as
    relates to any potential future human clinical
    trials, based off the animal data available,
    correlate to be anticipated at 20-30mg q.d. or
    b.i.d. for such focused toward
    neurogenic-dependent/neuroregenerative/anti-neurod
    egenerative (Alzheimer's Disease, et. al.)
    antidepressant, mood stabilizing, and
    anti-addiction treatments. Dosage that would
    appear to be of benefit for less critical
    conditions and/or cognitive enhancement would
    appear to be at 5-15mg q.d. or b.i.d. Oral
    bioavailailability appears modest, but
    significant. Theoretical applications within
    sublingual hydroalcoholic-glycerin based
    tinctures may be significantly superior.

6
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  • 4. The Key Benefits Of Sarms J-147 Powder
  • Improving Memory
  • Improving Diabetes
  • Improving the brain function
  • Protecting Neurons
  • Enhancing the learning ability
  • Increasing the attention
  • Preventing and treating senile dementia
  • Preventing Alzheimer's Disease
  • Relieving the anxiety
  • Improving Mitochondrial Function And Longevity
  • Fights Pain And Neuropathy

7
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  • What's the highlights of the report on J-147
    Powder testing?
  • In a different experiment, the scientists tested
    J147 powder cas 1146963-51-0 against Aricept
    (generic donepezil), the most widely prescribed
    Alzheimer's drug, and found that it performed as
    well or better in several memory tests.
  • Administered in the food of the aged and
    genetically engineered mice, J147 powder was able
    to reverse, even at that late stage in the
    disease, memory deficits after only three months
    of treatment.
  • Researchers found that while both drugs --
    Aricept and J147 powder -- improved short-term
    memory, only J147 powder improved spatial
    memory. They also found that combining the drugs
    worked better than either alone.
  • J147's ability to repair neuronal damage could
    make it useful in treating other
    neurodegenerative diseases such as Parkinson's.
  • J147 powder cas 1146963-51-0 has low toxicity
    and actually reverses damage in neurons
    associated with Alzheimer's.

6. Are There Any Side Effects When Using J-147
Powder? J-147 raw Powder cas 1146963-51-0 is
susceptible to heat so it is kept in
temperature-controlled medical fridges until the
time of packaging. Shipments are hand-delivered
to the post office at specific times in order to
avoid exposure to heat for long periods of time
while in the care of postal services. This
ensures that J-147 raw powder cas 1146963-51-0
you receive is as pure as possible. ATTENTION
This compound is for research purposes only. As
with all chemical compounds, there are risks
involved with the use of J-147 raw powder cas
1146963-51-0. Please consult a physician and the
available research before consumption. This
product is not intended to diagnose, treat, cure
or prevent any disease.
8
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7. What product can take place of Sarms J-147
powder? A more effective version called T-006
powder when combining tetramethylpyrazine and
J147 powder(taking a methoxyphenyl group of J147
powder cas 1146963-51-0 replacing it with
tetramethylpyrazine). R
9
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48695 So here is what you need to make my more
effective alternative to J147 powder
online Curcumin (as Turmeric and Ginger) - I
like to use this combo as a supplement
Tetramethylpyrazine (as Ligusticum wallichii or
Chocolate and Natto) Other Ingredients If Making
Food-Version (Black Pepper, Stevia, Salt) You can
either supplement both or make them into a food
(both have different effects for me). If you are
going to supplement J147 powder china
metabolizes into CAD-31 in the brain. CAD-31
enhancing the use of free fatty acids for energy
production by shifting of the metabolic profile
of fatty acids toward the production of ketone
bodies, a potent source of energy in the brain
when glucose levels are low. R Thus you could
supplement Ketones (empty stomach in morning) or
go on a Ketogenic Diet To make the food version
(1 week supply) Melt 3 bars of Dark Chocolate
with 3 tbsp of Coconut Oil in pot or saucepan
Add 2 tbsp of this specific powdered Natto to
chocolate Add 2 tbsp of Turmeric, 2 tbsp of
Ginger, 2tsp of Black Pepper powder (can add
pinch of Salt or Stevia for sweetness) Let cool
(and eat) or freeze then eat/snack
10
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8. What's the difference between -147 And
T-006? 1. Effects of supplementing for J-147
powder(exp over 1 month) Improved vision and
smell Increased memory
11
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48695 Increased mental clarity 2. Effects from
food version of T-006 powder (exp over 3 months)
Increased overall energy Increased verbal
fluency/acuity Reduced brain fog Calmer stomach
Better stools
9. More SARMS Powder For Choosing 1. AC262356
CAS 870888-46-3 2. LGD3303 CAS
1196133-39-7 3. SR9011 CAS 1379686-29-9 4.
MK-677/Ibutamoren CAS159752-10-0 5. YK11
CAS431579-34-9 6. RAD140/Testolone
CAS1182367-47-0 7. LGD-4033/VK5211, Ligandrol
CAS1165910-22-4
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48695 8. GW 501516/Cardarine CAS317318-70-0 9.
SR9009 CAS1379686-30-2 10. S4/Andarine CAS
401900-40-1 11. S23 CAS 1010396-29-8 12. MK
2866/Ostarine CAS841205-47-8 13. Trestolone
Acetate/MENT CAS6157-87-5
10. Where To Get J-147 Powder source? AASraw is
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