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Stem Cell Development

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Multipotent: Can become any cell within a specific germ layer or cell lineage ... Sea Urchin Development. One Cell to Blastula Stage. Early Mouse. Development ... – PowerPoint PPT presentation

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Title: Stem Cell Development


1
The Science and Ethics of Stem Cell Research
Stem Cell Development
2
An Overview of Early Development
modeled with Play-Dough
Fertilized egg
Multipotent
3
The Zygote
  • Take your Play-dough, and make one egg and sperm.
  • Combine the egg and sperm. Congrats you just had
    fertilization occur. You now have a zygote.

4
The Zygote
5
What your zygote might look like
6
Morula
  • Now its time for your zygote to grow and divide
    into more cells. The ball of cells is called a
    morula.
  • Take your Play-dough, and divide the zygote into
    two cells.

7
Early Cell Division
Source Florida Institute for Reproductive
Science and Technologies
8
Morula
  • Your cells continue to divide through a process
    called mitosis.
  • Now divide the two cells into a total of four
    cells.

9
Four-cell stage 2 days after fertilization
Source Florida Institute for Reproductive
Science and Technologies
10
Morula
  • Now divide the four cells again into a total of
    eight cells.

11
Eight-cell stage3 days after fertilization
Courtesy RWJMS IVF Program
Source Florida Institute for Reproductive
Science and Technologies
12
Morula
  • Your now ready for the final division to make
    your complete morula!
  • Now divide the eight cells into a total of
    sixteen cells.

13
Morula 4 days after fertilization 16
cells
Source Florida Institute for Reproductive
Science and Technologies
14
What your morula might look like
15
Blastula
  • Now your morula cells are ready to differentiate
    and make placenta or embryo cells.
  • Take another color of Play-dough to make the
    pre-placenta.

16
What your blastula might look like
17
Blastula5 days after fertilization
Source Florida Institute for Reproductive
Science and Technologies
Courtesy RWJMS IVF Program
18
Five Day Embryo- The Blastula starts to form a
hollow ball
http//www.nationalgeographic.com/ngm/
19
Blastula- now it attaches itself to the uterus
wall
This image has been released into the public
domain.
20

Sea Urchin Development One Cell to Blastula Stage
  • http//www.luc.edu/depts/biology/dev/urchindv.htm
  • (courtesy of Dr. J. Hardin, Univ. of Wisconsin)
  • http//www.exploratorium.edu/imaging_station/galle
    ry.php?AssetcelldivCategoryseaurchinsTypevide
    o

21
Early Mouse Development One Cell to Morula Stage
22
Early Human Development
23
Gastrula
  • Now your embryo cells from your blastula are
    ready to differentiate into three new layers.
  • Take two more colors of Play-dough to make the
    inner, middle, and outer layer.

24
What your gastrula might look like
25
(No Transcript)
26
The Three Layers
  • Outer Layer stem cells from this layer
    differentiate into skin cells, nervous system,
    pituitary gland, salivary glands
  • Middle Layer stem cells from this layer
    differentiate into bones, heart, muscles, testes,
    ovaries, kidneys
  • Inner Layer stem cells from this layer
    differentiate into pancreas, thyroid gland,
    liver, parts of the digestive system

27
Multipotent
This graphic has been released into the public
domain
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