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Actinomyces

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Actinomyces & Nocardia Actinomyces A.israelii, A.naeslundii; Gram positive; sulfur granule; Related to decay tooth and peridentitis ACTINOMYCES Anaerobic, filamentous ... – PowerPoint PPT presentation

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Title: Actinomyces


1
Actinomyces Nocardia
2
Actinomyces
  • A.israelii, A.naeslundii
  • Gram positive sulfur granule
  • Related to decay tooth and peridentitis

3
ACTINOMYCES
  • Anaerobic, filamentous, gram positive bacillus
  • Exhibit true branching
  • Mykes Greek for fungus
  • Thought by early microbiologist to be fungi
    because of
  • Morphology
  • Disease they cause

4
Clinical specimensActinomycosis-pus
5
ACTINOMYCOSIS
  • Not highly virulent (Opportunist)
  • Component of Oral Flora
  • Periodontal pockets
  • Dental plaque
  • Tonsilar crypts
  • Take advantage of injury to penetrate mucosal
    barriers
  • Coincident infection
  • Trauma
  • Surgery

6
Actinomycosis
  • A chronic suppurative and granulomatous???disease
    of the cervico-facial, thoracic or abdominal areas

7
ACTINOMYCOSIS
  • Form indurated masses with fibrous walls and
    central loculations with pus
  • Pus contains "Sulfur Granules"
  • Gritty, yellow white
  • Average diameter - 2mm
  • Composed of mineralized mycelial mass
  •  
  • Chronic infection
  • Form burrowing sinus tracts to skin or mucus
    membranes
  • Discharge purulent material

8
Actinomycosis - sulfur granule
9
Pulmonary Actinomycosis
  • 15 of cases
  • Aspiration of organism from the oropaharynx
  • Slowly progressive process involving lung and
    pleura
  • May be mistaken for malignancy
  • Chest pain, fever, wgt loss and hemoptysis

10
Mycetoma(???)
  • Streptomyces species?

11
Nocardiosis
  • Subcutaneous infections, pulmonary infections,
    and brain abscesses
  • N. asteroides N. brasiliensis

12
Lab. Diagnosis
  • Clinical SpecimensSputum,Pus,Biopsy tissue

Sulfamethoxazole-Trimethoprim
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