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Probiotics A Possible Answer To Decreasing Immune System Health Digestive Problems Nationally $107 billion in direct health care expenditures in 1992. 200 million ... – PowerPoint PPT presentation

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Title: Probiotics

  • A Possible Answer To Decreasing Immune System

Digestive Problems Nationally
  • 107 billion in direct health care expenditures
    in 1992.
  • 200 million sick days, 50 million physician
    visits, 16.9 million school days lost, 10 million
    hospitalizations, almost 200,000 deaths per
  • Digestive tract cancers are responsible for
    117,000 deaths/yr, non-cancerous digestive
    diseases cause 74,000 deaths/yr.

  • Quality of an individuals immune system can be
    evaluated through the Th1/Th2 balance
  • Th1Cops Th2Armed Forces
  • A healthy immune system is balanced and dynamic,
    switching back and forth as needed.
  • Inadequate Th1 response can result in chronic
    infection, chronic fatigue syndrome cancer.
  • Overactive (but paradoxically ineffective) Th2
    response can contribute to allergies and
    syndromes and have a role in autoimmune disease.
  • Combination of failure of Th1 and overactive, but
    ineffective, Th2, are seen in a wide variety of
    chronic illnesses AIDS, chronic fatigue
    syndrome, candidiasis, multiple allergies, viral
    hepatitis, cancer, lupus, and many others.

  • If the two arms of the immune system can be
    balanced by stimulating Th1 cells and decreasing
    Th2 cells, then many symptoms of theses illnesses
    would diminish or disappear.
  • With adequate exposure to viruses, bacteria, and
    microorganisms, our Th cells mature in proper
    proportion into Th1 cells, but without enough
    exposure our cells are prone to overreactions and
    likely to mature into Th2 cells.

  • Dysbiosis is an intestinal imbalance where
    pathogenic microorganisms outnumber beneficial
    bacterial species.
  • Digestive diseases are often caused in part by or
    result in dysbiosis.

Early Development
Major Causes
Common Symptoms
Why should YOU care?
  • Chemical farming and pesticides have lead to
    sterilization of soil and water (chlorination).
  • Antibiotics, hormones, and other drugs are given
    to chickens and cattle used for food.
  • Stress, medications, and typical American diet
    all promote dysbiosis.

What MORE do we know?
  • Probiotics are live active cultures that are
    supposed to improve the balance of the gut
    microbiota, with specific effects, in particular,
    the immunomodulatory potential of specific
  • The strains with the most beneficial properties,
    potential sources of probiotics, belong most
    frequently to the genera Bifidobacterium and

Special Probiotics
  • Homeostatic Soil Organisms (HSOs) are specific
    probiotic strains of microorganisms found in the
  • In nature, HSOs help plants digest inorganic
    substances, protect roots from parasites, yeast,
    and fungi, and provide growth factors and
    different hormones.
  • When ingested orally in a probiotic formulation,
    may have advantages over non-HSO probiotic
    formulas, due to ability to implant and survive
    in the gut.

The Researcher
  • A Natural Hygiene Practitioner and a University
    Professor of Gastroenterology, Rheumatology, and
    Clinical Nutrition since 1979, Dr. Goldberg has
    long been devoted to helping others reverse
    chronic illnesses through Natural
    Hygienic/Biological Measures.

PAUL GOLDBERG, M.P.H., D.C.Natural Hygiene
Practitioner, Professor, Educator, and
The Study
  • Background
  • A theory known as the hygiene hypothesis,
    suggests that many people in modern societies
    have been too highly protected from normal
    bacteria. This isolation from the bacteria in our
    environment, according to the hygiene hypothesis
    may contribute to the rise in chronic
    degenerative diseases such as asthma,
    inflammatory bowel diseases, and a host of
    allergic conditions.

The Study
  • Hypothesis
  • Anecdotal evidence suggests that a variety of
    gastrointestinal, allergic, autoimmune, and
    degenerative conditions, can be affected
    positively by the consistent (3 months or longer)
    administration of an HSO formulation. This pilot
    study was undertaken to explore the possible
    advantages of clinical responses in subjects with
    a variety of medically unresponsive chronic
    disease conditions of at least 3 years duration.

The Study
  • Subject Selection Criteria
  • Had a medically diagnosed chronic condition.
  • Had condition for at least 3 yrs (mean of 5.5
  • Condition did not positively respond to medical
  • 18 years old or older
  • Not currently taking any corticosteroids,
    antibiotics, or other drugs that might mask study
  • Agreed to follow study protocol for 120 days.
  • Undergo case history/physical examination and
    have following blood tests a)Blood Chemistry,
    b)Complete Blood Count with Differential, c)
    Blood Lipids
  • Required to provide stool sample pre and
    post-study for microbiological analysis including
    bacteriology and mycology.
  • No cases accepted who ingested alcohol beyond 2
    drinks a week, tobacco in any form or amount, or
    any other recreational drug use for a period of
    not less than 60 days prior to the study.

The Study
  • Protocol
  • Subjects took 18 caplets of Primal Defense
  • HSOs per day for 120 days with following
  • instructions
  • Take 6 caplets 3x a day on empty stomach with 8
    ounces of water.
  • Drink sufficient water
  • Take adequate care of general health, by avoiding
    processed foods, getting sufficient rest and
    sleep, and not engaging in toxic habits,
    specifically alcohol, tobacco, or any other drugs
    other than needed prescription medications.

  • 16 of 17 subjects completing study reported
    improvements in their symptoms, including
  • partial to complete relief from bowel problems
  • decreases in asthmatic symptomology
  • increases in energy levels
  • improvements in skin conditions
  • improvement in chronic sinus infection
  • general improvements in overall well-being.
  • No subjects reported any worsening of symptoms at
    completion of study.

What does it mean?
  • The HSOs work in a similar way in the human
    intestinal tract as they do with plants,
    providing a line of defense as well as growth
    factors and nutrients, which together result in
    overall increased health.
  • HSOs are able to implant and survive well in the

Are the findings credible?
  • The testing methods and findings both are backed
    by numerous other similar clinical tests done for
    specific problems or diseases using HSOs.
  • Suspect point Were diet and other restrictions
    actually responsible for results more than HSOs?

Further Research
  • High cholesterol study
  • Energy levels, memory and concentration study
  • Chronic Lymphcytic Leukemia stage II study

More on HSOs
  • HSOs Pool New RNA/DNA in the Cells
  • HSOs Quench Free Radicals by Creating SOD
  • HSOs Stimulate Alpha Interferon Production
  • HSOs Stimulate the Production of Human Lactoferrin

Further Reading
  • The reduction of Candida albicans "yeast"
    overgrowth using Fungal Defense and Primal
    Defense along with lifestyle modifications a 23
    patient pilot study.
  • Complementary treatment of Chronic Digestive
    Disorders with Malabsorption Syndrome using HSOs.
  • Portal to the interior viral pathogenesis and
    natural compounds that restore mucosal immunity
    and modulate inflammation.

  • Patient Heal Thyself by Jordan S. Rubin
  • Probiotics by Erik Isolauri, Seppo Salminen,
    Arthur C. Ouwehand, from Best Practice and
    Research Clinical Gastrointerology Vol. 18, No.
    2, pp. 299-313, 2004.
  • Homeostatic Soil Organisms as a Treatment for
    Chronic Disease ConditionsA Pilot Study by Dr.
    Paul Goldberg