Turner Syndrome

1
Turner Syndrome

• By Olivia Hoefling

2
What is Turner Syndrome?

• Turner Syndrome is a genetic syndrome that
  effects every 1 in 2,500 females.
• Most females are born with 2 x chromosomes, but
  females with Turners Syndrome are only born with
  one x chromosome (or part of one).

3
What are the physical symptoms?

• A webbed neck (extra folds of skin)
• A low hair line at the back of the neck
• Drooping at the eyelids
• Lower set ears
• Abnormal bone development
• Extra fluids in hands in feet
• Short stature
• Lack of sexual development

4
How do you inherit Turners?

• Turners Syndrome is neither dominant or
  recessive.
• It is caused by nondisjunction
• When a pair of sex chromosomes fails to separate
  during the formation of an egg (or sperm)

5
Inheritance of Turners continued

• As the embryo grows and the cells divide, every
  cell of the baby's body will be missing one of
  the X chromosomes.
• Turners is not inherited from a parent because
  women with Turner syndrome are usually sterile
  and cannot have children.

6
How is Tuners diagnosed?

• A doctor can easily suspect Turners by physical
  abnormalities, and blood tests can confirm this.
• The point when Tuners can be diagnosed depends
  on the severity of the condition and how quickly
  it develops.

7
What is the life expectancy of someone with
Tuners?

• Turners does not affect a persons life span.
• However, Women with Tuner Syndrome are faced with
  health risks such as heart disease, diabetes,
  kidney problems, etc.

8
How can Tuner Syndrome be treated?

• Growth hormones Can increase height.
• Ex. Androgen
• Estrogen Replacement Therapy Can promote
  development of secondary sexual characteristics
  as well as help maintain good bones and healthy
  tissue.

9
Are there any new treatments or research for
Tuners?

• Women with Turner Syndrome are infertile.
• However, with the use of reproductive
  technologies have been used to help woman with
  Turners become pregnant.
• Ex. A donor egg can be used to create an embryo,
  which is carried by the Turner syndrome woman.

10
Statistics

• 1 in every 2,500 live female births are affected
  by Turner Syndrome
• 0.04 of U.S. population is affected.
• 108,800 people in the U.S. are affected.

11
What is everyday life like for someone with
Turner Syndrome?

• Depending on the severity of the condition, a
  woman with TS generally lives a normal life.
• However, TS does involve more health risks
  (heart, kidney) so someone with TS has to have
  regular check ups and doctors appointments.
• Cont

12
Everyday Life Continued

• Though women with TS are just as intelligent as
  anyone else, some may experience learning
  difficulties.
• Learning difficulties may include trouble in
  mathematics, spacial skills, and hearing problems
• Continued

13
Everyday Life Continued

• Women with TS have physical abnormalities, so
  this is something that they have to deal with in
  social situations every day.
• This can greatly affect these girls self esteem
  and confidence so some sort of therapy is
  recommended.

14
Bibliography

• http//en.wikipedia.org/wiki/Turner_syndrome
• http//kidshealth.org/teen/diseases_conditions/gen
  etic/turner.html
• http//www.medicinenet.com/turner_syndrome/article
  .htm
• http//learn.genetics.utah.edu/content/disorders/w
  hataregd/turner/
• http//genetics.emedtv.com/turner-syndrome/diagnos
  is-of-turner-syndrome.html
• http//serendip.brynmawr.edu/exchange/node/1741