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ALOPECIA

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Title: ALOPECIA


1
ALOPECIA
2
WHAT IS ALOPECIA?
  • IT IS ABSENCE OR LOSS OF HAIR

3
FORMS OF ALOPECIA
  • AREATA-BALD SPOTS PATCHY HAIR LOSS
  • TOTALIS-COMPLETELY BALD OR WITH LITTLE VISIBLE
    HAIR ON SCALP
  • UNIVERSALIS-NO VISIBLE HAIR ON BODY
  • CICATRICIAL-SCARRING HAIR LOSS

4
ALOPECIA AREATA
Current evidence suggests that alopecia areata is
caused by an abnormality in the immune system.
This particular abnormality leads to
autoimmunity. As a result, the immune system
attacks particular tissues of the body. In
alopecia areata, for unknown reasons, the body's
own immune system attacks the hair follicles and
disrupts normal hair formation. Biopsies of
affected skin show immune cells inside of the
hair follicles where they are not normally
present. What causes this is unknown. Alopecia
areata is sometimes associated with other
autoimmune conditions such as allergic disorders,
thyroid disease, vitiligo, lupus, rheumatoid
arthritis, and ulcerative colitis. Sometimes,
alopecia areata occurs within family members,
suggesting a role of genes and heredity.
5
ALOPECIA AREATA
6
Is alopecia areata hereditary?
  • Yes, heredity plays a role. In one out of five
    persons with alopecia areata, someone else in the
    family also has it. Those who develop alopecia
    areata for the first time after the age of thirty
    years have less likelihood that another family
    member will have it. Those who develop their
    first patch of alopecia areata before the age of
    thirty have a higher possibility that other
    family members will also have it.

7
ALOPECIA TOTALIS
  • Alopecia totalis is the loss of all head hair.
    Its causes are unclear, but it is an autoimmune
    disorder. Stress is sometimes thought to be a
    contributor to the hair loss caused by alopecia,
    however many people leading relatively
    stress-free lives have experienced the symptoms.

8
ALOPECIA TOTALIS (CONTD)
  • In alopecia totalis, immune system cells called
    white blood cells attack the rapidly growing
    cells in the hair follicles that make the hair.
    The affected hair follicles become small and
    drastically slow down hair production.
    Fortunately, the stem cells that continually
    supply the follicle with new cells do not seem to
    be targeted. So the follicle always has the
    potential to regrow hair.

9
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10
IS THERE A DIFFERENCE BETWEEN AREATA AND TOTALIS?
  • For all practical purposes, a few patches of
    hair loss is called Alopecia areata while total
    hair loss all over the head, including eyebrows,
    eyes lashes is called Alopecia totalis.
  • The treatment approach is different and the
    prognosis is also difference. That is, Alopecia
    Areata is treatable with great success, while
    Alopecia totalis is not curable using homeopathy.
    Steroids may help but superficially. Our
    experience suggests that by use of steroids, most
    patients get more spots elsewhere on the skin.
    Steroids do not address internal autoimmune
    disorder. But, they are very useful during acute
    attacks.

11
ALOPECIA UNIVERSALIS
  • The most advanced form in a series of conditions
    all related to the same disease, Alopecia
    Universalis is characterized by total a loss of
    body hair. A member of the group of hair loss
    conditions called Alopecia Areata, the only
    difference between Alopecia Universalis and it's
    variants is the extent of hair loss.

12
ALOPECIA UNIVERSASLIS (CONTD)
  • Patients are usually otherwise healthy, but have
    more thyroid disease and vitiligo than the
    general population. Those with vitiligo (patchy
    loss of skin color) may also develop AU in time.
    Many individuals with Alopecia Universalis are
    born with some hair, but then begin losing it
    very quickly. The disorder is inherited as an
    autosomal recessive trait. It is caused by a
    mutation in a gene dubbed HR in chromosome band
    8p21.2 that is the human homologue of the mouse
    "hairless" gene -- the human version of the gene
    in the mouse that is responsible for hairless
    mice.

13
ALOPECIA UNIVERSALIS (CONTD)
  • Is the "hairless" gene only found in people with
    Alopecia Universalis? Most likely. Based on the
    known research, we can safely assume that only
    individuals with this rare and severe form of
    Alopecia Areata carry the gene. Unfortunately,
    there have not been enough studies done to verify
    that this is true of all those afflicted.

14
ALOPECIA UNIVERSALIS (CONTD)
  • Aside from genetic tendencies, the contributing
    causes of Alopecia Universalis are not known. It
    is important that those with it are careful to
    protect themselves from the sun, bacteria, and
    other potentially harmful elements, as the scalp,
    nasal cavity and eyes are not protected.
    According to the National Alopecia Areata
    Foundation, other than the hair, nails can also
    be affected. The nail involvement may be limited
    to pinprick indentations, all the way to severe
    distortion of the entire nail. Alopecia
    Universalis may be acute and short-lived, or
    remain permanently. The possibility of regrowth
    does remain however, even for those with 100
    hair loss for many years. Predicting when
    regrowth may occur is not currently possible.

15
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16
ALOPECIA IN CHILDREN
  • Hair loss in children is actually not very
    common, however it is significant enough that
    nearly 2 Million children suffer from at least
    one form of Alopecia (hair loss) or another in
    the United States alone. The good news is that at
    least 60 of children with Alopecia will
    "outgrow" the condition without need for
    treatment. As with all forms of Alopecia, a
    reversal and complete restoration of hair takes
    time - sometimes up to a year or more, but for
    the vast majority of children, it will
    spontaneously resolve. The bad news is that 40
    wont have such luck, which can be quite
    frustrating both for the parents and the child
    affected by this often cosmetically embarrassing
    condition.

17
CHILDREN WITH ALOPECIA
  • Please keep in mind hair loss in children is not
    due to vitamin deficiencies (unless extreme
    malnutrition is present), poor scalp circulation,
    headbands, hats, or cold weather. Diagnosis is
    typically as simple as an evaluation of the risk
    factors a visual examination of the type of loss,
    and some tests your doctor can perform.
  • Alopecia is not life-threatening, and children
    who have it are otherwise healthy. Why the hair
    falls out from the roots is still a mystery. What
    is known is that the condition is not contagious,
    caused by foods, or the result of nervousness,
    hyperactive disorders, or psychological stress.
    In 20 of cases another family member has been
    affected. Some patients with this condition will
    also develop a grid-like pitting of the nails.

18
CICATRICIAL ALOPECIA
  • The cause of the various cicatricial alopecias is
    poorly understood. However, all cicatricial
    alopecias involve inflammation directed at the
    hair follicle, usually the upper part of the
    follicle where the stem cells and sebaceous gland
    (oil gland) are located. If the stem cells are
    destroyed, and the sebaceous gland as well, there
    is then no possibility for regeneration of the
    hair follicle and permanent hair loss results.

19
WEBSITES AND SUPPORT GROUPS
  • WWW.ALOPECIAWORLD.COM
  • CHILDRENS ALOPECIA PROJECT
  • NATIONAL ALOPECIA AREATA FOUNDATION
  • WEBMD FOR INFO
  • WWW.HAIRLOSSTALK.COM
  • GOOGLE ALOPECIA AND FIND OTHER RELATED SITES.

20
DEDICATED TO JOSE CHARQUENOMY PELONSITO
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