Gene Therapy - PowerPoint PPT Presentation

Loading...

PPT – Gene Therapy PowerPoint presentation | free to download - id: 3c3be7-NmRjZ



Loading


The Adobe Flash plugin is needed to view this content

Get the plugin now

View by Category
About This Presentation
Title:

Gene Therapy

Description:

Gene Therapy Genetic Engineering of Bacteria to Produce Human Proteins Genetic Engineering of Bacteria to Produce Human Proteins Genetic Engineering of Bacteria to ... – PowerPoint PPT presentation

Number of Views:353
Avg rating:3.0/5.0
Slides: 15
Provided by: blufftonE
Learn more at: http://www.bluffton.edu
Category:
Tags: gene | therapy

less

Write a Comment
User Comments (0)
Transcript and Presenter's Notes

Title: Gene Therapy


1
Gene Therapy
2
Genetic Engineering of Bacteria to Produce Human
Proteins
3
Genetic Engineering of Bacteria to Produce Human
Proteins
Human blood clotting gene
human cell
bacterial DNA
Insert bacterial/human DNA into bacterial cell
4
Genetic Engineering of Bacteria to Produce Human
Proteins
5
Gene Therapy
  • An experimental treatment which attempts to treat
    a disease by inserting a gene into the cells of a
    human
  • gt3000 patients have been treated in gt300 clinical
    trials around the globe
  • No gene therapy treatment is yet approved for
    general use

6
Jesse Gelsinger
  • - received gene therapy for OTC Deficiency
  • - died September 1999

7
Gene Therapy for OTC Deficiency
8
Patricia Simons, December 1999
  • I ask you to let these trials continue. Its
    the only hope the parents and children have.
    Dont make this one more dream differed for them.
    Sadly, patients die in the name of medical
    science, and we all know that. Gene therapy is
    just beginning. Please give it a chance.

9
Severe Combined Immunodeficiency(SCID)
  • The first disease to be treated with gene therapy
  • Persons with SCID lack a functional immune system
    and are susceptible to severe infections

10
David Vetter (1972-1984)
- lived in a sterile plastic bubble because had
a single defective gene that caused Severe
Combined Immunodeficiency (SCID)
11
Gene Therapy for SCID
12
Ashanthi DeSilva- inherited SCID -received 1st
ever gene therapy in 1990
13
Gene Therapy for SCIDUsing Long-lived Umbilical
Cord Blood Cells
14
Andrew Gobea( mom)- inherited SCID- received
1st ever gene therapy using long-lived cord blood
cells
15
Other Partially Successful Gene Therapy Trials
  • therapy to induce new blood vessel growth in
    patients with blocked heart arteries or with
    other circulatory problems
  • therapy to induce brain tumor cells to commit
    suicide

16
Ethical Questions Concerning Gene Therapy
  • Should treatments be used to change the
    appearance, intelligence, or athletic ability of
    healthy people?
  • Should parents be allowed to genetically
    manipulate their children before birth?
  • Should gene therapy be allowed that alters
    germ-line cells (reproductive cells that will
    pass the altered genes to future generations)?

17
David Vetter (1972-1984)- lived in a sterile
plastic bubble because had a single defective
gene that caused Severe Combined Immunodeficiency
(SCID)
18
Ashanthi DeSilva- inherited SCID -received 1st
ever gene therapy in 1990
19
Andrew Gobea( mom)- inherited SCID- received
1st ever gene therapy using long-lived cord blood
cells
20
Jesse Gelsinger
  • - received gene therapy for OTC Deficiency
  • - died September 1999
About PowerShow.com