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Functional Aspects of Dairy Foods An Overview W. James

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Title: Functional Aspects of Dairy Foods An Overview W. James


1
Functional Aspects of Dairy Foods An Overview
  • W. James Harper
  • Department of Food Science Technology
  • The Ohio State University

2
Functional Foods
  • Functional foods have been defined as any food
    or food ingredient that may provide a health
    benefit beyond the traditional nutrients that it
    contains.
  • Many foods and their components, including dairy
    foods, fit this definition

3
Functional Dairy Foods
  • In the early 1980s, the Japanese were the first
    to recognize dairy components as having
    significant contributions to physiologically
    functional foods. Since then there has been an
    increasing number of investigations that have
    supported this view.

4
Functional Dairy Foods
  • Current evidence for the health benefits of most
    dairy foods and dairy components is based
    primarily on in vitro and in vivo animal studies
  • Human clinical studies are still needed in many
    areas

5
Bioactive Functions Associated with Dairy
Products and their Components
6
Significant Functions
  • Anti-microbial including control of gut
    microflora
  • Anti-viral
  • Binding of E coli and cholera enterotoxins
  • Anti-cancer
  • Immunomodulation
  • Anti-oxidative
  • Opioid effects
  • Retard osteoporosis

7
Cardiovascular Functions
  • Anti-inflammatory
  • Anti-hypertensive
  • Anti-thrombic
  • Cholesterol reduction

8
Dairy Products and Milk Components with
Bioactive Functions
9
Dairy Products
  • Yogurt and other fermented dairy foods
  • Milk
  • Colostrum
  • Cheese
  • Whey Protein Concentrates/Isolates
  • Milk Protein Concentrates

10
Almost All Milk Components May Contribute
Potential Health Benefits - Including
  • Proteins
  • Peptides
  • Lipids
  • Minor Carbohydrates
  • Minerals
  • Vitamins

11
Relationship between Bioactive Function and Milk
Components
12
Protection from Some Cancers
  • Whey protein concentrates
  • Bovine Serum albumin
  • Lactoferrin
  • Alpha-lactalbumin
  • Peptides
  • Sphingolipids
  • Conjugated Linoleic Acids (CLA)
  • Butyric acid
  • Calcium

13
Immunomodulation
  • Modified whey protein concentrate
  • Lactoferrin
  • Lactoperoxidase
  • Kappa casein glycomacropeptide
  • CLA
  • Probiotics fermented dairy foods
  • Colostrum

14
Protection from Hypertension
  • Whey protein concentrates
  • Immune milk protein concentrates
  • Probiotics
  • Peptides
  • B-vitamins
  • Calcium ?

15
Anti-Thrombic Activity
  • Whey protein concentrates
  • Lactoferrin
  • Peptides

16
Anti-Inflammatory Effects
  • Peptides
  • Colostrum
  • Immune whey protein concentrates

17
Reduction of cholesterol levels
  • Whey protein concentrates
  • Whey protein isolates
  • Stearic acid

18
Anti-microbial/ Anti-viral
  • Whey protein concentrates
  • Lactoferrin
  • Lactoperoxidase
  • Lactoferrin
  • Casein glycomacropeptide

19
Toxin Binding Effects
  • Whey protein concentrate
  • Alpha-lactalbumin
  • Beta-lactoglobulin
  • Casein glycomacropeptide

20
Promotion of Bifidobacterial Growth
  • Casein glycomacropeptide
  • Amino sugars
  • Oligosaccharides

21
Probiotics
  • Lactic acid microorganisms assist in control of
    the gut microflora
  • Yogurt
  • Fermented drinks
  • Strongly strain dependent
  • Supported by some clinical studies

22
Opioid Like Effect
  • Peptides
  • Derived from alpha-lactalbumin
  • Derived from beta-lactoglobulin
  • Derived from caseins

23
Antioxidative Effects
  • Whey Protein Concentrates/Isolates
  • Lactoferrin
  • Vitamin C

24
Highlighting Some Components Not Covered In
Detail In This Symposium
25
Lactoferrin
  • Natural SECRETION of milk, tears and bile
  • Elevated by inflammation and in some cancers
  • Animal studies have shown addition of lactoferrin
    provides some protection against some cancers

26
Lactoferrin (continued)
  • Anti-bacterial
  • Anti- viral
  • Anti-thrombic
  • Iron transport
  • Immunomodulation
  • Toxin binding properties

27
Peptides
  • Peptides from both caseins and whey proteins are
    bioactive
  • End product of digestion of proteins
  • Growing recognition that in vitro and in vivo
    results do not always give the same effects
  • Multiple functionality

28
Peptide Functions Include
  • Anti-microbial/Anti-viral/ Toxin binding
  • Anti-hypertension
  • Anti-inflammatory
  • Immunomodulation
  • Anti-cancer
  • Appetite Control
  • Opioid Effects

29
Casein Glycomacropeptide
  • Cancer Prevention
  • Immunomodulation
  • Diet Suppression
  • Cardiovascular Effects

30
In Conclusion
  • Almost all components of milk have a
    physiological function beyond nutrition
  • Milk components are multifunctional
  • Dairy foods possess a natural cluster of
    nutrients that protect health and enhance the
    immune system.
  • More human clinical studies are needed to prove
    efficacy in all cases
  •  
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