Proposal to Expand Biomedical Engineering Education and Research at UB Through the Creation of a Dep

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Proposal to Expand Biomedical Engineering
Education and Research at UB Through the Creation
of a Department of Biomedical EngineeringDean
Harvey StengerSchool of Engineering and Applied
SciencesProfessor of Chemical and Biological
EngineeringDean Michael CainSchool of Medicine
and Biomedical SciencesProfessor of Medicine and
Professor of Chemical and Biological Engineering
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Medicine------------------J. Canty G. Suzuki T.
Cimato V. Iyer J. Fallatovia
Radiology------------------S. Rudin D. Bednarek
Pharmacy------------------B. Straubinger
Physiology and Biophysics------------------F.
SachsA. OlszowkaD. PendergastC. Lundgren

• Biomedical Engineering------------------V.
  Govindaraju
• V. Chaudhaury
• Zhang
• J. Xu
• S. Neelamegham
• S. Andreadis
• E. Tzanakakis
• D. Taulbee
• H. Meng
• V. Krovi
• Patra
• S. Hua
• H. Chopra
• J. Mollendorf
• T. Kesavadas

Pediatrics------------------D. Swartz
Expanding research between engineering and health
sciences.
OrthopedicSurgery------------------L. Bone
Biochemistry------------------T. Lee G. Willsky
Pathology Anatomical Sciences------------------
J. Kolega F. Mendel
Library Information Systems ------------------M.
Ruiz
Pediatric Surgery------------------S. Lau M.
Caty
Neurosurgery ------------------L.N. Hopkins E.
Levi K. Hoffman
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Task Force (Design Team)

• Professor Stelios Andreadis Chemical and
  Biological Engineering/Center for Bioengineering
• Professor Vipin Chaudhary Computer Science and
  EngineeringProfessor Kenneth Hoffmann
  Neurosurgery/Toshiba Stroke Center/School of
  MedicineSr. Associate Dean Suzanne Laychock
  Medical School/Pharmacology and
  Toxicology/School of MedicineProfessor Hui Meng
  Mechanical and Aerospace Engineering/Toshiba
  Stroke Center (SEAS)Professor Sriram
  Neelamegham Chemical and Biological
  Engineering/Center for BioengineeringProfessor
  David Pendergast Physiology and
  Biophysics/School of MedicineProfessor Murali
  Ramanathan Pharmaceutics/Neurology/School of
  PharmacyProfessor Randall Rasmusson Physiology
  and Biophysics/School of MedicineProfessor
  Albert Titus Electrical EngineeringSr. Vice
  Provost and Executive Director Bruce Holm, NYS
  CoE in Bioinformatics and Life Sciences

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Why Biomedical Engineering?

• Strong impact on clinical medicine
• Examples
• Implantable Cardioverter Defibrillator
• Neuro-Imaging
• Magnetic catheter guidance
• Strong impact on health care costs
• Impact on both individuals and on corporations
• A distinct and growing field of education,
  employment and research
• A direct impact on a regions economy and health
  care industry
• Foster and expand collaborative interdisciplinary
  research
• A positive impact on student quality
• Responsibility for important facilities and
  programs

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Example 1 Predicting when implanting a
cardioverter defibrillator is necessary
Sudden Cardiac Death Rates Are Not Improving
Overall Coronary Artery Disease (CAD) Mortality
is Declining
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Best hope identify individuals at high risk and
implant an ICD ImplantableCardioverterDefibrilla
tor
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ICDs save lives in heart attack survivors

• BUT
• lt1 in 5 patients actually need the device
• gt10 million Americans now qualify for
  prophylactic ICDs
• gt200 billion cost to the health care economy

MADIT II study NEJM, 2002
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Methods for Mapping and Imaging Arrhythmias
Electrocardiographic Imaging (ECGI)
Intraoperative mapping
Catheter Mapping
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Example 2 Guiding catheters to repair and
prevent Atrial Fibrillation
LSPV
RSPV
RIPV
LIPV
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Creating a magnetic field to direct the catheter
Movie SL13
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Movie SL12
Moving the catheter
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The Operating Room
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Cardiologist repairing the heart
Movie SL41
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Distinct and growing field of research and
education
Figure 1 Growth of accredited engineering
programs in Chemical, Environmental, and
Biomedical Engineering.
Figure 3 Per faculty research expenditures by
discipline.
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Biomedical Engineering Economic Impact

• Medical Instruments
• Market Capitalization 222B
• e.g. Alcon, Boston Scientific, Stryker
• Medical Appliances
• Market Capitalization 180B
• e.g. Medtronic, Biomet, Varian
• Biotechnology
• Market Capitalization 297B
• e.g. Genentech, Amgen

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Biomedical Engineering Demand

• Biomedical engineering jobs will increase by 31.4
  percent through 2010
• United States Department of Labor
• Median annual earnings of biomedical engineers
  were 60,410 in 2002
• Bureau of Labor Statistics
• Biomedical engineering BS candidates received
  starting offers averaging 52,355 a year, and MS
  candidates, on average, were offered 61,000 in
  2005.
• National Association of Colleges and Employers

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Why Biomedical Engineering at UB?

• To expand and facilitate interdisciplinary
  synergistic research programs
• To create accredited training curriculum,
  overseen by both schools
• To facilitate attracting outstanding faculty
  leaders and students
• To meet the growing regional need for a trained
  workforce, continuing education, research
  collaboration, and intellectual property

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Research Focal Area I

• Molecular-Cellular, Cell and Tissue Engineering

Areas of emphasis at UB currently include
vascular inflammation, cardiovascular mechanics,
angiogenesis, skin tissue engineering, wound
healing, cardiovascular tissue engineering, bone
tissue engineering/bone implants, stem cells
(embryonic and adult), biomaterials, drug
delivery, pharmacokinetics/ pharmacodynamics,
gene delivery (viral and non-viral vectors), high
throughput strategies for cell and tissue
behavior (genomics, proteomics, Glycomics,
metabolomics), metabolic engineering and protein
engineering.
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Research Focal Area II

• Computational Biomedical Engineering and Modeling

Areas of emphasis at UB currently include ion
channel biophysics, single molecule biophysics,
cellular and systems electrophysiology, cardiac
arrhythmias, gynecology and obstetrics, neural
networks, renal hemodynamics, biomedical pattern
recognition, hemodynamics, anatomical
visualization, multiple sclerosis,
pharmacogenomics, drug design, modeling
drug-target interactions, data mining.
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Research Focal Area III

• Biomedical Sensors, Instrumentation, and
  Diagnostics

Areas of emphasis at UB include development of
microelectronic devices for sense and response
creation of micro-fluidic devices for drug
delivery and diagnostics development of in vivo
devices for therapy and monitoring creation of
ex vivo devices for diagnostics and
experimentation creation of minimally invasive
devices for health monitoring development of
medical monitoring systems instrumentation
development for medical research and
instrumentation development for human performance
in hazardous or extreme environments.
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Research Focal Area IV

• Medical Imaging and Analysis

At UB, the areas of emphasis in this field
include development of high resolution detectors
for x-ray, computed tomography (CT), positron
emission tomography (PET) and single photon
emission computed tomography (SPECT) and
development of 2D and 3D analysis of images from
radiography, angiography, PET, SPECT, micro-CT,
as well as high-resolution magnetic resonance
imaging (MRI) and functional MRI (fMRI).
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Proposed Curriculum for Bachelor of Science in
Biomedical Engineering 132 Credit Hours
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Direct impact on the regions economyRegional
company executives endorsing our proposal

• Tom Hook, CEO Greatbatch
• Bill Burns, CEO Minrad
• Tom Stewart, CEO Gaymar
• David Barthel, CEO Smartpill
• Ted Grasela, CEO Cognigen
• Bob Burrier, VP RD Invitrogen
• Tim Levindofske, President, CEO Reichert
• Paul Buckley, CEO Applied Sciences
• Ravi Bansal, CEO Airsep
• Heather Erickson, President Medtech
• Bob Brady, Martin Berardi, Moog Inc.

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Five Year Goals for BME program and department

• Eight full time faculty who are tenured or in
  tenure tracks within the department of BME.
• An internationally recognized chairperson for the
  department.
• Twenty affiliated faculty who actively supervise
  PhD students majoring in BME.
• Graduation rates of 45 B.S., 20 M.S. and 10 Ph.D.
  students per year. Total enrollments of 180
  undergraduates and 90 graduate students
• Research expenditures of 3,000,000 per year by
  the eight core departmental faculty.
• A strong and active corporate affiliates program,
  enhanced by the department leading the NYSTAR
  Center for Advanced Technology in BioMedical
  Engineering
• Over 50 peer reviewed publications co-authored by
  the PhD and MS students in the BME program per
  year.
• More than 8 patent disclosures and 4 patent
  submissions per year by the core faculty.

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Thank you!