Statin Interactions with NNRTIs and PIs

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Statin Interactions with NNRTIs and PIs
Joanne J. Orrick, PharmD, AAHIVE Faculty,
Florida/Caribbean AETC orricjj_at_ufl.edu
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Affect of PIs on Statin Levels
1. Reyataz Prescribing Information, Bristol-Myers
Squibb Co, September 2008 2. Busti AJ, et al. J
Cardiovasc Pharmacol, 2008, 51(6) 605-610. 3.
Prezista Prescribing Information, Tibotec Inc,
October 2008. 4. Sekar VJ, et al. 8th
International Workshop on Clinical Pharmacology
of HIV Therapy, Budapest, April 2007, abstract
54.
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Affect of PIs on Statin Levels
1. Lexiva Prescribing Information,
GlaxoSmithKline, March 2008. 2. Crixivan
Prescribing Information, Merck Co Inc, April
2008.
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Affect of PIs on Statin Levels
1. Carr TA et al. 40th ICAAC, Toronto, September
2000, presentation 1644. 2. Kaletra Prescribing
Information, Abbott Laboratories, June 2008 3.
Hoody D, et al. 14th Conference on Retroviruses
and Opportunistic Infections, Los Angeles,
February 2007, abstract 564. 4. Hsyu PH,
Schultz-Smith MD, Lillibridge JH, et al.
Antimicrob Agents Chemother, 2001, 45 3445-3450.
5. Viracept Prescribing Information, Agouron
Pharmaceuticals Inc, August 2007.
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Affect of PIs on Statin Levels
1. Invirase Prescribing Information, Roche
Pharmaceuticals, July 2007. 2. Fichtenbaum CJ,
et al. AIDS, 2002, 16(4) 569-577. 3. Van
Heeswijk R et al., 5th International Workshop on
Clinical Pharmacology of HIV Therapy, Rome, April
2004, abstract 5.2. 4. Aptivus Prescribing
Information, Boehringer Ingelheim, June 2008. 5.
Pham P, et al. 15th Conference on Retroviruses
and Opportunistic Infections, Boston, February
2008, abstract 767.
.
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Affect of NNRTIs on Statin Levels
1. Rescriptor Prescribing Information, Pfizer
Inc, June 2006. 2. Castro JG Gutierrez L. Am J
Med, 2002, 112505. 3. Sustiva Prescribing
Information, Bristol-Myers Squibb Company, March
2008. 4. Gerber JG, et al. J Acquir Immune Defic
Syndr, 2005, 39(3) 307-12.
.
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Affect of NNRTIs on Statin Levels
1. Scholler-Gyure M et al. 4th IAS Conference on
HIV Pathogenesis, Treatment Prevention, Sydney,
July 2007, abstract WEPEA106. 2. Intelence
Prescribing Information, Tibotec Pharmaceuticals
Ltd, January 2008. 3.
.