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The Reproductive and Genetic Revolution: THE ETHICS OF

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Title: The Reproductive and Genetic Revolution: THE ETHICS OF


1
The Reproductive and Genetic RevolutionTHE
ETHICS OF A TECHNOPOLY
2
Religion Art Family
TECHNOPOLY
TOTALITARIAN TECHNOCRACY
Politics History Truth
Privacy Intelligence
3
DEHUMANIZED
BRAVE NEW WORLD
UTOPIA
4
Humanity has reached a turning point in dealing
with the results of the alienation of the
product from its producer at personal and social
levels.
5
narcissistic sense of freedom
TECHNOPOLY-DICTATED CULTURAL MOVEMENTS
Deist or Nietzchean View of God
6
  • Human Cloning
  • Genetic Engineering
  • Ectogenesis
  • Artificial Sperm
  • Ovarian Banking and Transplant

7
Part One Human Cloning
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Somatic Cell Nuclear Transfer
ASEXUAL
AGAMIC
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ALL HUMAN CLONING IS REPRODUCTIVE
  • NO HUMAN CLONING IS THERAPEUTIC

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PARTHENOGENESIS
  • Unfertilized, immature oocytes are placed in a
    mix of chemicals known to prompt cell division
  • Chemicals and elements in the cytoplasm of the
    egg join up to mimic the fertilizing action of a
    normal sperm
  • The inner cell mass cells are isolated from the
    trophoblast tissue and are subject to culturing
    process to form pluripotent stem cell lines
  • Tissue transplants

26
The Ethics of SCNT Parthenogenesis
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The life of innocent human beings is inviolable.
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Every human being is an individual with a
concomitant right to his or her own unique
genotype, identity and a life never before lived.
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Every human being is an end to be loved not a
means to be used for anothers end.
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Every human being is of equal value to every
other human.
31
Every human being is sexual by nature and the
capacity to reproduce sexually is a basic human
need and is integral to human dignity.
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Every human being has the right to be conceived,
gestated, and brought up within marriage, that
is, within a family.
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The vocation of biomedical technologists and
researchers is to serve the needs of man and of
human society.
35
Debate on the issue of therapeutic cloning and
whether it ought to be legalized, if it is going
to be ethical debate, ought to be honest and
transparent.
36
Part Two Genetic Engineering
37
Somatic Gene Therapy
  • Effective in treating single- gene defects
  • Some progress in cancer treatments, growth of
    new blood vessels, and in treating SCID

38
BONE MARROW
GENE-BEARING VIRUS
GENETICALLY ALTERED STEM CELLS
STEM CELLS ISOLATED
39
Ethics of Somatic Cell Genetic Therapy
  • If it could be safely executed in utero, the
    technology could be moral.
  • If somatic cell therapy is done post-natally, as
    in the SCID therapies, and uses non-embryonic
    stem cells, it is also ethical research and it
    also fulfills the true goal of biomedical
    research
  • Somatic cell genetic enhancement could be unjust
    if it would require large amounts of health care
    resources for non-therapeutic enhancement

40
Germline Genetic Engineering
  • Like vaccinations
  • Dont stop with the patient
  • Involves the direct manipulation of genetic
    material in germline cells
  • Altered genome will be inherited by all
    succeeding generations

41
Ethics of Germline Genetic Engineering
  • Assaults human dignity, moral health of society
  • Directly attacks human life
  • Commodifies the human being
  • Pressures parents to design their children
  • Easily driven by eugenics
  • Deprives the patient of giving his or her consent
  • Risks unknown debilitating factors
  • Co-opts the creation of human lifeGods work
  • Misconceives the nature of science and research

42
Part Three Ectogenesis
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Ectogenesis
  • Endometrial biopsy
  • Disassociate cells
  • Seed cells
  • Add insulin, growth
  • factors and hormones
  • Co-culture embryos

Hung-Ching Liu, PhD Center for Reproductive Medici
ne and Infertility Cornell University
44
Ethics of External Wombs
  • Not intrinsically evil
  • If used before it was proven safe or to study the
    mechanisms of human implantation, it would be
    immoral
  • If used as an incubator, it could be moral

45
Ethics of External Wombs
  • If used to replace in vivo gestation, or to avoid
    stretch marks, it would be immoral
  • If it encourages and extends the externalization
    and commodification of conception, gestation, and
    birth, it has the propensity for immoral use
  • If this research produced endometrial tissue
    transplants that did not involve co-cultured
    human embryos, ESCs or cloning, it could be moral.

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Part Four Artificial Sperm
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ARTIFICIAL
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Artificial Sperm
  • Take female somatic cells from one woman
  • Submit them, in vitro, to artificial
    haploidization
  • Haploid (or artificial sperm) fertilizes a mature
    human oocyte

49
Ethics of Artificial Sperm
  • Every human being is sexual and to reproduce
    sexually is a basic human good
  • Every new human being is a gift
  • Purpose of science serve the individual and
    common good

50
Part Five Ovarian Banking and Transplant
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OVARIAN BANKING AND TRANSPLANT
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Ovarian Banking and Transplant
  • Freezing the whole organ
  • One group of rats received frozen/thawed ovaries
    another group fresh ovarian transplants
  • 10 weeks post-transplant, blood tested for FSH
    and estradiol-17B
  • Ovaries prepared for histology to assess ovarian
    follicle reserves

53
The lab rats which had been transplanted with
frozen/thawed ovaries had normal numbers of
ovarian follicles including graafian stages.,
54
One of 7 animals which received frozen/thawed
ovaries was pregnant with two healthy fetuses
implanted on either side of the uterine
anastomosis
55
Ethics of Ovarian Banking Transplantation
  • Not immoral in and of itself
  • For woman undergoing sterilizing chemo, it is
    morally good
  • For woman with gene for premature menopause,
    could be morally good
  • For woman who would have her ovaries removed and
    banked for a rainy day, it would be immoral.

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The Reproductive and Genetic RevolutionTHE
ETHICS OF A TECHNOPOLY
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