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Mental Health Screening: A PhRMA Friendly Remedy for Societal Problems


52 million school children and 6 million staff ... SSRI Antidepressants--Zoloft, Celexa, Lexapro, Desyrel. Anti-anxiety drug--Ativan ... – PowerPoint PPT presentation

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Title: Mental Health Screening: A PhRMA Friendly Remedy for Societal Problems

Mental Health Screening A PhRMA Friendly Remedy
for Societal Problems
  • Vera Sharav
  • President, AHRP
  • December 12, 2005

  • Orwellian nightmare
  • New Freedom Commission Recommends
  • screening the entire US population for mental
  • 52 million school children and 6 million staff
  • TeenScreen will increases number of children
    labeled with psychiatric illness
  • TMAP Rx guidelines promote increased sales of
    highest price psychotropic drugs

Mental health crisis or marketing strategy?
  • The unprecedented increase in children being
    diagnosed with psychiatric conditions and
    prescribed psychotropic drugs can be traced to
    the collaborative efforts of the drug industry,
    organized psychiatry, and government.
  • A series of federally sponsored mental health
    initiatives, promoted the idea that childrens
    mental health was in crisis, and early
    intervention is essential.
  • The Rx intervention 91 of the time
  • is drugs.

Rx for U.S. children98 off-label
  • 1995-1999 psych Rx for
  • stimulants up ------------------------------------
    -------- 23
  • SSRI antidepressants up -------------------------
  • 7-12 age group increased ------------------------
  • ------------------- 580
  • mood stabilizers up 40-fold ----------------------
    ----------- 4,000
  • Atypical antipsychoticsincreased
    ------------------------ 300

  • IMS Health 2000
  • The drugs have not shown benefit than placebo
  • No other society prescribes psychoactive
    medications to children the way we do.
    Lawrence Diller, MD, pediatrician

Are U.S. Children So Different?IMS
  • what it means to be mentally healthy is subject
    to many different interpretations that are rooted
    in value judgments that may vary across
  • A Report of the Surgeon General, 1999
  • Childhood and adolescence being developmental
    phases, it is difficult to draw clear boundaries
    between phenomena that are part of normal
    development and others that are abnormal.

  • World Health Org
  • "The DSM-IV criteria remain a consensus without
    clear empirical data...the behavioral
    characteristics specified in DSM-IV, despite
    efforts to standardize them, remain
    subjective... p. 1163

After 30 yearswheres the science?
  • Patients have been diagnosed with chemical
    imbalances despite the fact that no test exists
    to support such a claim...there is no real
    conception of what a correct chemical balance
    would look like.
    Psychiatrist David Kaiser, MD
  • After almost 30 years, researchers have not
    developed any standardized tool for diagnosing or
    treating psychiatric disorders. NYT, 2005
  • diagnostic uncertainty surrounds most
    manifestations of psychopathology in early
    childhood Dr. Benedito Vitiello, NIMH, 2001

Mental Health Screening Eugenics revisited
  • Eugenics Psychiatry
  • Ideologically Driven by Flawed Theories
  • Arsenal of unproven biological-genetic theories
  • of mental illness and bad behavior
  • Eugenicists blamed genesbad blood
  • Psychiatrists blame chemical imbalance
  • But where is the evidence for either?

In the absence of science Pseudo Science
  • Flawed methodology
  • Eugenics Psychiatry use invalid surveys to
    screen for mental behavioral problems
  • suggestive questions
  • subjective interpretation
  • lack scientific criteria
  • open to bias prejudice

TeenScreen Manufacturing Illness
  • 14 questions vague, suggestive, loaded
  • -- In the last year, has there been a time
  • when you felt you couldn't do anything well or
    that you weren't as good-looking or as smart as
    other people?
  • when you couldnt think as clearly or as fast as
  • Have you often felt very nervous when you've had
    to do things in front of people?
  • 30-50 screen positive as mentally ill
  • What is the scientific criteria?

TeenScreen False Claims
  • TeenScreen promotes itself as
  • a model for early intervention--suicide
    prevention http//
  • Screening is an accurate predictor for mental
    health problems that may develop into more
    serious conditions. Screening is the first
    often most important step in identifying a
    condition. http//www.teenscreen
  • US Preventive Services Task Force refutes claim
    no evidence that screening for suicide reduces
    either suicide attempts or mortality. There is
    little evidence on the accuracy of screening
    tools. May 2004

TeenScreen 16 accuracy
  • TeenScreen tested in 7 NYC schools
  • 1,729 students
  • 475 students screened positive.
  • However, 84 non-suicidal teens being referred
    for evaluation for every 16 suicidal youths
    correctly identified.
    Dr. David Shaffer,JAACAP 2004
  • 84 false positives invalidates
  • any screening tool

Govt Endorsed Mental Health Dragnet
  • TeenScreen operates at 461 sites in 43 states
  • 122,000 adolescents screened in 2005
  • up from 14,000 in 2003
  • --- 350 Colorado students were screened twice
  • --- 50 were declared suicidal
  • "This year, we believe we will be able to
    identify close
  • to 10,000 teens in need, a 300 percent increase
    over last year."
    (Laurie Flynn, Testimony 2004)
  • TeenScreen
  • a conduit for expanding mental health system and
    increasing use of psychotropic drugs

Screening is- just the beginning
The long-term goal of TeenScreen is not just
identification but treatment. L.
Flynn, 2005
Dark Side of Screening
  • Psychiatric label impacts the course of a childs
  • stigma
  • loss of autonomy
  • loss of decision-making authority
  • discrimination
  • abuse

Legacy of Eugenics
  • Schools as screening laboratories
  • defectives morons defined high grade
    defectives lacking self-control
  • restless, fidgety, cannot keep still,
    odd definition fits diagnostic criteria of
    psychiatrys current catch-all diagnosis
  • attention deficit hyperactivity disorder--ADHD).
  • Screening for mental defects
  • 72,600 Americans involuntarily sterilized
  • children as young as 10 were sterilized

Medicating Aliah, Mother Jones, 2005
13 year old Aliah Gleason
Aliah Gleason, Victim of Screening
  • Aliah is one of 19,404 Texas teens subjected to
    involuntary mental health treatment in a state
    funded program July-Aug, 2004.
  • She was
  • screened falsely labeled suicidal
  • abused with physical and chemical restraints
  • forced to take psych drug cocktails that were
    never tested for safety or efficacy
  • cut off from contact with her parents for 9
  • Evidence-based treatment or child abuse?

Drugs prescribed for Aliah Gleason, age 13
  • SSRI Antidepressants--Zoloft, Celexa, Lexapro,
  • Anti-anxiety drug--Ativan
  • Two "atypical antipsychotics-- Geodon and
  • An older antipsychotic--Haldol
  • Two anticonvulsantsTrileptal, Depakote
  • Anti-Parkinson's drug--Cogentin
  • At her discharge from a State mental hospital
  • Aliah was on 5 different psych drugs
  • Risperdal was added to her cocktail
  • Evidence-based based medicine or child abuse?

Most psych drugs not approved for children
  • Most psych drugs carry Black Box warnings--the
    most serious warning placed in the labeling of a
    Rx medication.
  • Warnings for antidepressants
  • Twofold increased risk of suicidality
  • compared to placebo
  • FDA-2005 suicidal thinking or behavior due to
    drug can be expected in about 1 out of 50 treated
    pediatric patients.
  • Behavioral toxicitya.k.a. activation
    emotional lability anger, irritability,
    agitation, hostility, aggression, violent
    outbursts, mania, psychosis, and suicidal
    homicidal behavior

Rx drug cocktailsCompound risks
  • "it is sedating and would make it difficult for a
    child to experience the world in a normal way. If
    you or I were on that regimen we would have a lot
    of trouble attending to work or school. We don't
    have any idea what that combination of
    medications does to a developing child. It may
    have a number of long-term side effects.
  • Dr. Joseph Woolston,
    Yale University

Rampant drugging of foster children
  • Investigations across the U.S. found abusive use
  • psychotropic drugsas chemical restraints.
  • At greatest risk disadvantaged, poor children
    treated within state mental health systems
  • clinics, hospitals, foster care juvenile
  • 5560 foster children
  • Rx anticonvulsants / antidepressants
  • multi-drug cocktails
  • drugged children driven to suicidal violence
  • Even toddlers

Rx does not reflect severe risks
  • Depression diagnosis in children (7 to 17)
  • more than doubled in 5 years
  • 1.44 million in 1995-1996
  • 3.22 million in 2001-2002
  • SSRIs most widely used
  • 76 increase in 1995-1996
  • 81 increase in 2001-2002
  • 11 million Rx SSRIs in 2003
  • Psychotherapy declined as SSRIs rose

  • Stanford U study, 2005
  • Rx ignore SSRI failure to demonstrate clinical
    benefit placebo in children

TMAPalgorithms Rx blockbuster sales
  • TMAP (Texas Medication Algorithm Project)
  • began 1995 under (then) Gov Bush
  • Collusion pharmaceutical companies, U of Texas
    psychiatrists, mental health corrections
  • Contributions to Texas Mental Health Dept
  • Pfizer -----------------------------------
  • Janssen-J J-------------------------
  • Eli Lilly----------------------------------
  • TMAP mandates use of the most expensive psych
    drugs as first line treatmentwithout regard for
    drug hazards.

TMAP Primary beneficiaries
  • Texas Medicaid Expenditures 1998-2003
  • Pfizer Zoloft, Geodon, Neurontin -- 233
  • J J (Janssen) Risperdal ------------ 272
  • Lilly Prozac, Zyprexa ------------------ 403
  • CBS-KEYE News
  • TMAP boosted U.S. sales nationally
  • Sales antidepressants -- 13 billion
  • Sales antipsychotics --- 8.8 billion

Antipsychotics safety hazards
  • Approved only for adults with schizophrenia and
  • Warnings include Black Box
  • increased risk of death in elderly
  • hyperglycemia diabetes mellitus-insulin
  • acute weight gain100lbs not unusual
  • cardiovascular complications seizures
  • akathisiaa catalyst for suicidal and homicidal
  • 8,000 patients sued Eli Lilly Zyprexa-induced
    diabetes. 700 million settlement.

U.S. Sales of antipsychoticsTMAP expands a
small market
Medicaid Pays the Bill
  • Since 2000 mental health costs increase
  • more than 50
  • 63 of mental health spending public funds
  • 300 billion per year
  • Report, Parity-Plus A Third Way Approach to Fix
    Americas Mental Health System, June 22, 2005 by
    the Progressive Policy Institute.
  • Nationwide, Medicaid programs purchase an
    estimated 60 to 75 of antipsychotic drugs.
  • San Francisco Chronicle, October 23, 2005

California Expenditure New Antipsychotics
  • Cost of 4 of 10 top MediCal meds
  • Drug (brand name) Amount spent
  • 1. Zyprexa 248.9 million
  • 2. Risperdal 162.1 million
  • 4. Seroquel 142.3 million
  • 10. Abilify 68 million
  • Total Cost----------------------621--million
  • San Francisco Chronicle, October 23, 2005

TMAP guidelines Rx for disaster
  • Atypical antipsychotics safety hazards surpass
    all other Rx psychoactive drugs
  • Between 1996 to 2000 Texas Medicaid use of
    atypical antipsychotics in children 2 years
    increased 494.
  • from 28 million to 177 million in 2004.
  • Similar increases wherever TMAP was adopted
  • Of youth receiving antipsychotics, 42.9 had no
    history of or current psychosis. JBHSR, 2004

TMAP Impact Rx AntipsychoticsChildren
  • TennCare 1996-2001
  • Antipsychotics Rx in children nearly doubled
  • from 23 per 10,000 kids in 1996
  • to 45 per 10,000 kids in 2001
  • most dramatic increase
  • 6 to 12 kids (93 rise)
  • 13 to 18 teens (116 rise)
  • Use among preschool children (up 61)

TeenScreen paved the way for TMAP to scoop
them away A second wave is underway as ever
younger children are falling prey perhaps
never again to see the clear light of a drug
free day
Where have all the children gone? Theyre
being led astray by state licensed sorcerers
Beyond Orwellscreening infants the unborn
  • Dr. Adrian Angold (Duke) declared
  • One in 10 children aged 2 to 5 has severe
    psychiatric illness and such conditions begin
    very early in life, perhaps even in the womb.
    BBC 11-2005
  • He recommends
  • screening for and treating these disorders in
    babies and infants is the way forward.

Pathologizing the joy laughter of childhood
  • "During the manic phase of
    the illness
  • children may
    experience exceedingly
  • high self-esteem, an
    inflated sense of power or ability or may act as
    though they are in charge at home or school. They
    may act extremely happy, silly and giddy, but
    their moods can change rapidly.
  • Mania can be confused with ADHD
  • "We hope that by comparing these drugs and drug
    combinations, we might be able to find better
    ways to control this severe illness Dr. Luby
    Press Release, 2005

Bipolar Child epidemicU.S. Diagnostic
  • "Historically considered rare, childhood-onset
    bipolar disorder is now being reported more
    often, although its frequency remains an area of
    some controversy. (Carlson, 1990)
  • It is now recognized that pediatric bipolar
    disorders are highly prevalent and that they
    seriously disrupt the lives of children and
    adolescents (NIMH)
  • We are seeing an increasing number of very young
    children, ages 3-7 years, with sic frank
    symptoms of BP disorder. NIMH

TEAM (Treatment of Early Age Mania)no child
left behind
  • TMAP panelist Dr. Barbara Geller Dr. Joan Luby
    promote bioplar diagnosis in children
  • An extreme example involved a manic preschooler
    who believed that she made the sun rise and set."

NIMH Clinical Trials attempt to Justify
Illegitimate Drug Rx
  • Pediatric BPDcan be precipitated by
    antidepressant treatment. (Harvard Rev Psych,
  • Many of these young BPD patients have been
    treated with stimulants or antidepressants and
    few have been treated with mood stabilizing
    agents. Therefore, it is necessary to provide
    controlled studies of psychotropics in this
    younger bipolar population to provide clinical
    practice with an appropriate evidence-base. NIMH

Brandon the Bipolar Bear
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Diabolical Pathologizing
Who will bear responsibility?
  • for the harms likely to follow from mental
    health screening when children are wrongly
    labeled as having a mental illness?
  • for depriving children of a normal childhood?
  • for exposing 91 (9 out of 10) children referred
    for mental health services to psychoactive drugs?
  • Who will restore childrens drug damaged brains?

Who will restore the wondrous magical world of