Title: Current Status of Avian Influenza H5N1 Commonly referred to as the Bird Flu
1Current Status of Avian Influenza
(H5N1)(Commonly referred to as the Bird Flu)
- Teresa Y. Morishita, DVM, PhD, Dipl. ACPV
- Veterinary Extension
- The Ohio State University
2Avian Influenza
- Influenza Type A
- All subtypes can affect birds
- Poultry disease
- Waterfowl reservoirs
3Avian Influenza Subtypes
- Name based on surface proteins
- Hemagglutinin proteins
- H5, H7 subtypes
- Neuraminidase proteins
- N1
AI
4Avian Influenza
- Signs
- Respiratory Tract
- Sneezing
- Excess Discharges
- Swollen Sinuses
- Digestive Tract
- Diarrhea
- Neurological System
- Twisted heads
- Uncoordinated gait
5Avian Influenza
- Humans
- Respiratory Tract
- Flu-like
- Digestive Tract
- Diarrhea
6H5N1 Avian Influenza Timeline
- 1996 H5N1 from goose in Guangdong Province
- 1997 poultry farms and markets in Hong Kong
6/18 human fatalities - 2/03 1/2 human fatality travel to Fujian
Province 1/1 suspect
7First Wave of H5N1 Influenza
- Mid-03 H5N1 causes outbreaks, undetected and
unreported - 12/03 Two tigers and two leopards die of H5N1
avian influenza. FIRST CASE IN BIG CATS
8First Wave of H5N1 Influenza
- 12/03Korea
- 1/04 Vietnam, Japan, Thailand, Cambodia, Laos
- 2/04 Indonesia, China
- Human Cases
- 8/12 Thailand16/23 Vietnam
- Cannot rule out limited human-to-human contact
9Second Wave of H5N1 Influenza
- 6-7/04China, Indonesia, Thailand, Vietnam
- Possible role of wild birds
- More lethal for mammals fatal to waterfowl
- 7/04 Japan is disease-free
- 8/04 Malaysia infections in pigs and cats cat
was previously considered resistant - 9/04 Korea is disease-free
- 10/04 147/441 tigers in Thailand two eagles
from Thailand imported into Brussels domestic
ducks as reservoirs
- Human Cases
- 4/5 Thailand 4/4 Vietnam
10Third Wave of H5N1 Influenza
- 12/04 Indonesia, Thailand, Vietnam possibly
Cambodia and Laos - 1/05 Malaysia is disease-free
- 4/05 6,345 wild birds in central China
- 6/05 Chinas Xinjiang region
- 7/05 4/05 outbreak from new variant virus
transmitted among geese and may spread via
migratory routes civets infected Russian
poultry and wild birds - 8/05 Kazakhstan poultry and wild birds Tibet
Mongolia - 10/05 Turkey Romania songbirds from China
smuggled into Taiwan imported parrot in United
Kingdom Chinas Anhui and Hunan Province
Croatia wild birds Macedonia
- Human Cases
- human-to-human transmission
- 21/64 Vietnam 4/4 Cambodia Thailand and
Indonesia
11Patterns
- Spreading over land mass
- Need for expedient diagnosis
- Poultry involved
- Wild birds and migration routes
12Areas of Concerns
- Migratory Birds
- reservoirs
- overlap of summer breeding areas
13Areas of Concerns
- Illegal Commerce
- songbirds
- fighting chickens
- raw and undercooked products
"This is an old Polish recipe that was used at
Easter time. This recipe is traditionally served
with home made noodles. If desired the fruit can
be removed, leaving broth to serve with noodle.
If you do not know where to purchase a duck,
contact a local farmer or butcher. If you prepare
your own poultry be sure to add 1/2 cup vinegar
to duck blood to prevent coagulation." Original
recipe yield 12 servings.
14Areas of Concerns
- Commerce
- live bird markets
- transport of birds, mammals?
15Stopping a World Pandemic
- Human-to-Human Transmission
- Education
- Expedient Diagnosis, Isolation, Quarantine
16Contact Information
- Duane Rader
- Agriculture and Natural Resources
- Ohio State University Extension
- 1495 West Longview Avenue Suite 206
- Mansfield, OH 44906
- Phone 419-747-8755
- Fax 419-747-8770
- rader72_at_ag.osu.edu