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RECOMMENDATIONS TO THE CANCER PREVENTION AND RESEARCH INSTITUTE OF TEXAS CPRIT

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The Texas Cancer Clinical Trials Network (CTNet) will provide critical ... in advanced cancer imaging methods and offer opportunities for clinical research ... – PowerPoint PPT presentation

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Title: RECOMMENDATIONS TO THE CANCER PREVENTION AND RESEARCH INSTITUTE OF TEXAS CPRIT


1
RECOMMENDATIONS TO THECANCER PREVENTION AND
RESEARCH INSTITUTE OF TEXAS (CPRIT)
UNIVERSITY OF TEXAS WORKING GROUPSCLINICAL
TRIALS
COMPUTATIONAL BIOLOGY CANCER IMAGING
  • February 20, 2009

2
NEW CLINICAL TRIALS INFRASTRUCTURE IS NEEDED
  • Clinical trials determine whether or not a
    prevention program or treatment method works.
  • Patients receive better care when enrolled in
    clinical trials.
  • An integrated network of care providers will
    reach greater numbers of patients across various
    demographic groups while testing more complex
    treatment options such as personalized medicine.
  • The Texas Cancer Clinical Trials Network (CTNet)
    will provide critical infrastructure for
    partnerships in clinical trials.

Clinical Trials Working Group
2
3
THE TEXAS CANCER CLINICAL TRIALS NETWORK (CTNET)
  • Major functions
  • Provide scientific and administrative leadership,
    central operations, communications, oversight and
    accountability
  • Develop new standards for clinical research
    protocols, modern information technology, new
    relationships between academic researchers and
    community physicians, new strategies to
    strengthen the clinical research workforce, and
    new clinical research capacity in deficient areas
    and in resource poor settings.
  • Bring high quality cancer treatment to the
    communities where patients live and work

Clinical Trials Working Group
3
4
RESEARCH PRIORITIES
  • Health disparities
  • Prevention
  • Cancer therapy
  • Personalized medicine
  • Survivorship
  • Education and mentoring
  • Computational biology
  • Molecular imaging
  • Cancer nanomedicine

Clinical Trials Working Group
4
5
NEW COMPUTATIONAL BIOLOGY INFRASTRUCTURE IS
NEEDED
  • Additional funding is needed for large-scale
    computational biology-focused cancer prevention
    and clinical research
  • Increase integration of statewide clinical
    databases and tumor registries
  • Create a statewide virtual biobanking system
  • Create a Texas BioGrid a very large-scale
    bioinformatics software tool collaborative
    environment
  • Train the next generation of bioinformaticians
    needed to work in cancer computational biology
    and bioinformatics research

Computational Biology Working Group
5
6
NEXT STEPS NEEDED TO FORM THE TEXAS BIOGRID
  • Significantly improve the State of Texas
    biomedical database infrastructure
  • Increase informatics storage and computing power
    to support Texas cancer research
  • Create an integrated network and computing
    infrastructure at the state level
  • Establish Texas Centers for Cancer Computational
    Biology Research (TC3BRs)

Computational Biology Working Group
6
7
NEW CANCER IMAGING INFRASTRUCTURE IS NEEDED
  • Research capacity must be increased
  • Texas currently receives 5 of the National
    Cancer Institutes 640 million for imaging
    research because of a lack of infrastructure
  • This percentage is far below what TX population
    requires and what TX institutions could support
  • Practical imaging tools for patients are needed
  • Create new functional molecular imaging methods
    that measure specific physiological or
    biochemical parameters
  • Improve diagnostic evaluation of tumors
  • Expedite monitoring of treatment effectiveness
  • Establish the Cancer Imaging Network of Texas
    (CIN-Tx)

Cancer Imaging Working Group
7
8
FORMATION OF THE CANCER IMAGING NETWORK OF TEXAS
(CIN-TX)
  • Establish 3-4 cancer Imaging Centers of
    Excellence (COEs) to
  • Pioneer the development of one or two high-impact
    areas of imaging excellence
  • Train clinicians in advanced cancer imaging
    methods and offer opportunities for clinical
    research
  • Accelerate and transfer new imaging methods to
    the clinical trials network (CTNet)
  • Draw support from research teams from a variety
    of disciplines
  • Invite various investigators to participate in
    funding opportunities and partnerships

Cancer Imaging Working Group
8
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