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Muscle CSM 1040 Dr' Melanie Osterhouse

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Smooth walls of hollow visceral organs like stomach and bladder. Forces fluids thru ... Rigor mortis lets go when tissue breaks down, writers cramp) ... – PowerPoint PPT presentation

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Title: Muscle CSM 1040 Dr' Melanie Osterhouse


1
Muscle CSM 1040Dr. Melanie Osterhouse
  • Fxn of m skeletal m. is about 40 of body mass
  • a.
  • b.
  • c. d.

2
Types
3
Location and function
  • Smooth walls of hollow visceral organs like
    stomach and bladder
  • Forces fluids thru
  • Cardiac only in heart
  • Pumps blood
  • Skeletal
  • movement

4
Functional characteristics
  • Excitability
  • Contractility unique to m.
  • Extensibility
  • elasticity

5
Histology (slide 127)
  • Bundle of sticks (m. fibers) surrounded by C.T.
    called ___________
  • A cluster of perimysium-surrounded bundles- is
    surrounded by dense irregular C.T. called
    __________
  • _______ - plasma membrane of m. fiber
  • ________- m. fiber cytoplasm
  • ________- each m. fiber composed of ______
  • Each m. has 1 n., 1 a., 1 v. enters center of
    m. and branch through the CT sheets

6
Slide 130 and 129
  • Explain thick and thin filaments and bands
  • Thick are _______ and thin are ______
  • (do people demo)
  • Thin filament is troponin and tropomyosin
  • Tropomyosin blocks myosin heads from binding
  • Troponin binds Ca2

7
Slide 133 132
  • Action potential -gt Ca2 release -gt C12 binds to
    troponin -gt troponin exposes binding site for
    thick filament -gt ATP hydrolyzed so myosin head
    binds -gt ADP P released -gt myosin head rotates
    causing contraction -gt ATP binds to myosin -gt
    myosin head released from actin and recocks

8
Where does all the ATP come from?
  • Regeneration of the hydrolyzed ATP
  • ____________ - high energy molec stored in m
  • ________ ADP-gtcreatine ATP
  • __________- makes lactic acid (m. soreness)
  • After creatine is used up
  • Break down ________ stored in m.
  • For large amts of ATP for moderate periods (40
    sec)
  • ______ - prolonged light to moderate exercise
  • Occurs in mitochondria

9
Aerobic
  • Where does the O2 come from
  • _____- similar to Hb but in m. -gtstores o2
  • Glucose o2 -gt CO2 H2O ATP
  • 36 ATP per glucose but sluggish due to many steps

10
m. fatigue
  • Cannot contract m. even if still being stimulated
    (not just tired)
  • ________ - no ATP to unhook cross bridge stays
    contracted (ex. Rigor mortis lets go when
    tissue breaks down, writers cramp)
  • _______ - extra O2 the body must take in for
    restorative processes
  • Why you rapidly breathe after stopping exercise

11
Motor unit
  • Motor unit Motor n. and all m. fibers it
    supplies
  • When motor n. fires, all m. fibers it innervates
    contract
  • Fine motor control (eyeball) have few fibers per
    n.
  • Large m. that are less precise (hip m.) have lots
    of fibers per n.

12
Where does the Ca2 come from (slide 128)
  • ____________- stores Ca2 and releases it on
    demand ( during an action potential for ex.)
  • Surrounds each myofibril
  • ______- continuation of sarcolemma that conducts
    the impulses and orders the release of Ca2

13
Terms (slide 137)
  • ______ moving part
  • _______ immovable or less moveable bone
  • _____ same tension (same weight)
  • Concentric contraction - ________ (picking up
    book)
  • Eccentric contraction - _________(putting it
    back)
  • ________- same length (not lenthen or shorten)
  • Adding wt. but not moving
  • ______- even when relaxed, m. are almost always
    slightly contracted
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