Hunger and satiety in anorexia nervosa

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Hunger and satiety in anorexia nervosa
Maggie Dong Psyc 260
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Anorexia nervosaMental disorder Body weight 15
below expected

• How is hunger satiety represented in the brain?

• Anorexia nervosa
• Mental disorder
• Body weight 15 below expected

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• Explore anorexia-specific cognition to food

Food related behavior
Cognitive control mechanism
Medial prefrontal cortex
Visual stimulation of food
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Hypothesis
Anorexia Nervosa patients would show
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Participants 13 Anorexia patients10 Healthy
controlsAge 13 21Stimuli320 photos of
sweet savory food320 photos of non-food
objects

• Participants
• 13 Anorexia patients
• 10 Healthy controls
• Age 13 21
• Stimuli
• 320 photos of sweet savory food
• 320 photos of non-food objects

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• Procedure
• Two 30min sessions satiated hungry
• Rate hunger
• Rate photo pleasant, neutral, or unpleasant
• inside a fMRI head-coil

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Results
Hungry Satiated F(1,21) 98.2, pAnorexia (hunger) 7.8, pAnorexia (food) p 8
Discussion

• Anorexia Nervosa
• ? Responsive to pleasant aspect of food

Red satiated Green hungry
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Medication effectDuration of diseaseAgeCoexisti
ng medical conditionse.g., Depression

• Medication effect
• Duration of disease
• Age
• Coexisting medical conditions
• e.g., Depression

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Further researchHow do high- low-caloric food
affect brain activations in anorexia patients?

• Further research
• How do high- low-caloric food affect brain
  activations in anorexia patients?

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