RBC casts form when RBC leak through the GBM and are glued together with the mucoproteinous TammHors

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RBC casts form when RBC leak through the GBM and
are glued together with the mucoproteinous
Tamm-Horsfall proteins
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when cellular casts stay in the
nephron for some time before they are flushed
into the bladder urine, the cells degenerate to
coarse and then fine granular casts and finally
to waxy casts