Endocrine Medications - PowerPoint PPT Presentation

Loading...

PPT – Endocrine Medications PowerPoint presentation | free to view - id: 15d6a7-M2E3Z



Loading


The Adobe Flash plugin is needed to view this content

Get the plugin now

View by Category
About This Presentation
Title:

Endocrine Medications

Description:

Side Effects. Decreased appetite, N/V, diarrhea. Toxicity. Lactic ... Side Effects. Flatulence, cramps, abd distention, diarrhea, borborygmus. Hypoglycemia ... – PowerPoint PPT presentation

Number of Views:131
Avg rating:3.0/5.0
Slides: 32
Provided by: Anyo
Category:

less

Write a Comment
User Comments (0)
Transcript and Presenter's Notes

Title: Endocrine Medications


1
Endocrine Medications
  • Julie Balk
  • Nursing 220
  • March 21, 2005

2
Diabetes Mellitus
  • Types of DM
  • Complications
  • Short Term
  • Long Term
  • Diagnosis and Monitoring
  • Treatment Overview

3
Diabetes Mellitus
  • Type 1 Diabetes
  • Type 2 Diabetes

4
Complications of Diabetes
  • Short Term
  • Hyperglycemia
  • Hypoglycemia
  • Ketoacidosis
  • Long Term
  • Macrovascular Disease
  • Microvascular Disease
  • Pathys retinopathy, nephropathy, neuropathy
  • Others
  • Amputations, Inpotence, Gastroparesis

5
Diagnosis
  • FPG
  • Casual (Random) Blood glucose
  • Oral Glucose Tolerance Test

6
Type 1 Treatment
  • Goal is to maintain normal glucose levels
  • Diet
  • Self-monitoring (SMBG)
  • Exercise
  • Insulin replacement

7
Type 2 Treatment
  • Maintain Normal blood glucose
  • Diet
  • Exercise
  • Oral hypoglycemic agents
  • Insulin

8
Insulin
  • Seven Types of Insulin
  • Natural (1)
  • Modified Insulin (6 )
  • Lispro
  • Insulin Aspart (NovoLog)
  • Neutral Protamine Hagedorn (NPH)
  • Lente
  • Ultralente
  • Insulin Glargine (Lantus)

9
Sources of Insulin
  • Recombinant DNA Technology
  • Human Insulin Analogs
  • Lispro, aspart, glargine
  • Pork Pancreas
  • Beef Pancreas

10
Insulin Concentrations
  • 100U/ml (U-100)
  • 500 U/ml (U-500) Manufacturer Request

11
Insulin Pearls
  • Routes of Administration
  • Preparing the Injection
  • Sites of Injection
  • Mixing
  • Storage
  • Alternative Methods of Insulin Delivery
  • Jet Injectors, Pen Injectors, Portable Insulin
    Pumps, Implantable Insulin Pumps, Intranasal

12
Dosing Schedules
  • Conventional Therapy
  • Intensive conventional therapy
  • Continuous Subcutaneous Insulin Infusion

13
Insulin Treatment Complications
  • Hypoglycemia
  • Lipdystrophies
  • Allergic Rxn

14
Oral Hypoglycemics
  • Sufonylureas
  • Mechanism of Action
  • Adverse Effects
  • Hypoglycemia
  • Use in Pregnancy and Lactation
  • Cardiovascular Toxicity
  • Drug Interactions
  • Alcohol, Beta Blockers, other drugs that can
    cause hypoglycemia

15
Meglitinides
  • Mechanism of Action
  • Adverse Effects
  • hypoglycemia

16
Biguanides
  • Mechanism of Action
  • Indications
  • Side Effects
  • Decreased appetite, N/V, diarrhea
  • Toxicity
  • Lactic Acidosis
  • Drug Interactions

17
Rosiglitazones
  • Mechanism of Action
  • Side Effects
  • Fluid retention, edema, lipid effects
  • Monitoring
  • LFTs

18
Alpha-Glucosidase Inhibitors
  • Mechanism of Action
  • Indications
  • Side Effects
  • Flatulence, cramps, abd distention, diarrhea,
    borborygmus
  • Hypoglycemia
  • Liver dysfunction

19
Combination Products
  • Glyburide/Metformin
  • Glipizide/Metformin
  • Rosiglitazone/Metformin

20
Thyroid Disorders
  • Hypothyroidism
  • Hyperthyroidism

21
Hypothyroidsim
  • Requires replacement with thyroid hormones
  • Thyroid Hormone Preparations
  • Pure, synthetic compounds
  • Extracts of animal thyroid glands

22
Thyroid Supplements
  • Routes of Administration
  • Evaluation
  • Nursing Implications

23
Hyperthyroidism
  • Propylthiouracil
  • Mechanism of Action
  • Indications
  • Adverse Effects
  • Agranulocytosis, Hypothyroidism, Pregnancy and
    Lactations
  • Rash, Nausea, arthralgia, headache, dizziness,
    parathesias

24
Hyperthyroidism (cont)
  • 131 I
  • Indications
  • Advantages and disadvantages

25
Hypothalamic and Pituitary Rx
  • Growth Hormone
  • Prolactin
  • Thyrotropin
  • Corticotropin
  • Gonadotropins
  • Antidiuretic Hormone
  • Oxytocin

26
Adrenal Cortex Medications
  • Glucocorticoids
  • Mineralocorticoids
  • Adrenal Androgens

27
Replacement Therapy
  • Hydrocortisone
  • Cortisone
  • Fludrocortisone

28
Corticosteroid Synthesis Inhibitors
  • Ketoconazole
  • Aminogluthethimide

29
Drugs Affecting Uterine Function
  • Uterine Relaxants
  • MgSO4
  • Beta 2 Adrenergic Agonists
  • Calcium channel blockers
  • Indomethacin

30
Uterine Stimulants
  • Oxytocin
  • Ergot Alkaloids

31
Drugs for Cervical Ripening
  • Dinoprostone
  • Misoprostol
About PowerShow.com