Comparative Study of Capsule Opacification Between Accommodating and Monofocal Intraocular Lenses

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Comparative Study of Capsule Opacification
Between Accommodating and Monofocal Intraocular
Lenses

• Ivan Ossma Gomez,MD MPH 1 , 2
• Andrea Galvis, MD 1 , 3
• 1 Fundación Clinica Valle del Lili Cali,
  Colombia
• 2 Universidad Industrial de Santander
  Bucaramanga, Colombia
• 3 Fundación Oftalmológica de Santander
  Bucaramanga, Colombia

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Financial Disclosure

• Advanced Medical Optics E
• Alcon Laboratories Inc E
• Novartis Ophthalmics E
• Visiogen Inc E
• The Synchrony IOL is currently in Phase III FDA
  trials

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Study Population
Kruskal Wallis Analysis of Variance
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Rayner 18.3 months postop
Synchrony 20.1 months postop
Alcon SA60AT 17.9 months postop
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Anterior Capsule OpacificationMonth 12
Fishers Exact Test p0.41
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Clinical Experience Synchrony

• Good unaided distance, intermediate and near
  visual function 1,2,3
• Subjective and objective evidence of
  accommodative amplitude 4,5,6
• Stability of over 2 years 1,2
• Contrast Sensitivity Studies 7

1 Alarcon et al. ESCRS London 2006 2 Ossma et al.
ASCRS San Francisco 2006 3 Beiko G. ESCRS London
2006 4 Ossma et al. ASCRS San Diego 2004 5 Galvis
et al. ASCRS Washington 2005 6 Bohorquez et al.
ESCRS London 2006 7 Galvis et al. AAO Las Vegas
2006
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Distance Corrected Acuity
20/63
20/40
20/32
20/25
-LogMar
20/20
20/16
20/13
n63 pts
n97 pts
n71 pts
n13 pts
Binocular Implants
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Discussion

• Hurdles to overcome in PCO analysis
• Validity of system of analysis
• Area of interest to be measured
• Difficulties in obtaining adequate photography
• OSCA System
• Freely available

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Conclusion

• Elements in design of Synchrony Dual Optic
  Accommodating IOL
• Minimize ACO
• Minimize PCO
• Synchrony Dual Optic Accommodating IOL
• PCO rates comparable to those of monofocal square
  edge acrylic IOLs

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Thank you
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