SURVIVORSHIP LIVING WITH AND BEYOND CANCER CHILDRENS CANCER AND LEUKAEMIA GROUP Late Effects Treatme - PowerPoint PPT Presentation

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SURVIVORSHIP LIVING WITH AND BEYOND CANCER CHILDRENS CANCER AND LEUKAEMIA GROUP Late Effects Treatme

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SURVIVORSHIP. LIVING WITH AND BEYOND CANCER. CHILDREN'S CANCER AND LEUKAEMIA GROUP ... Children's Cancer and Leukaemia Group. Started in 1977 as UKCCSG / CLWP ... – PowerPoint PPT presentation

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Title: SURVIVORSHIP LIVING WITH AND BEYOND CANCER CHILDRENS CANCER AND LEUKAEMIA GROUP Late Effects Treatme


1
SURVIVORSHIPLIVING WITH AND BEYOND
CANCERCHILDRENS CANCER AND LEUKAEMIA
GROUPLate EffectsTreatment summaries11.9.08
2
our aim-survivors living well!
3
Childrens Cancer and Leukaemia Group
  • Started in 1977 as UKCCSG / CLWP
  • 22 centres over UK
  • Late effects working group from 1988

4
number of 5 yrs survivors
5
The BCCSS
  • B ritish
  • C hildhood
  • C ancer www.bccss.bham.ac.uk
  • S urvivor
  • S tudy

6
BCCSS study
  • 14,000 questionnaires
  • 1940 -1991 at diagnosis
  • survived 5 yrs and over 16 yrs
  • 66 no follow up

7
cumulative morbidity over 30yrs
Oeffinger 2006
8
Information from BCCSS
  • Deaths 3056 of 18,000 (3025 cause known)
  • non cancer 628 3x normal
  • circulatory 168 3x normal
  • respiratory 106 8x normal
  • suicides 23 no excess

9
major areas of concern
  • early death
  • second cancers
  • cardiovascular disease
  • renal dysfunction
  • severe musculoskeletal problems
  • endocrinopathies
  • fertility
  • neuropsychological problems

10
who is at risk?
  • radiation
  • high dose chemotherapy
  • brain tumours
  • bone tumours (limbs)
  • bone marrow transplants

11
THERAPY BASED LONG TERM FOLLOW UP
PracticeStatement (2nd EDITION, APRIL
2005)www.cclg.org.uk
o
12
aftercure www.aftercure.org
13
Fact sheets
14
treatment summaries
  • Surgery
  • Chemotherapy
  • Radiation

15
(No Transcript)
16
conclusion
  • increasing number of survivors
  • survivors age with time
  • pattern of late effects for disease and treatment
    given
  • large population based study a national
    treasure
  • accurate and comprehensive treatment summaries
    are essential
  • (CCLG and BCCSS - supported by CRUK)
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